Mabel Kamweli Aworh

ORCID: 0000-0003-4213-6929
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Bacteriophages and microbial interactions
  • Salmonella and Campylobacter epidemiology
  • Vibrio bacteria research studies
  • Escherichia coli research studies
  • Viral Infections and Vectors
  • Probiotics and Fermented Foods
  • Animal Diversity and Health Studies
  • Brucella: diagnosis, epidemiology, treatment
  • Antibiotic Use and Resistance
  • Hepatitis C virus research
  • Heavy Metal Exposure and Toxicity
  • HIV/AIDS Research and Interventions
  • Genomics and Phylogenetic Studies
  • Zoonotic diseases and public health
  • Animal Disease Management and Epidemiology
  • Hepatitis B Virus Studies
  • HIV, Drug Use, Sexual Risk
  • Mosquito-borne diseases and control
  • Bacterial Identification and Susceptibility Testing
  • Virology and Viral Diseases
  • Gut microbiota and health
  • Vaccine Coverage and Hesitancy
  • Enterobacteriaceae and Cronobacter Research

Fayetteville State University
2025

North Carolina State University
2020-2024

African Field Epidemiology Network
2013-2024

Federal Ministry of Agriculture and Rural Development
2013-2023

Ahmadu Bello University
2019-2022

National Primary Health Care Development Agency
2022

Bridge University
2022

Technical University of Denmark
2020

Abstract Background Inappropriate use of antimicrobial agents in animal production has led to the development resistance (AMR) foodborne pathogens. Transmission AMR pathogens from reservoirs, particularly chickens human population does occur. Recently, we reported that occupational exposure was a risk factor for multidrug-resistant (MDR) Escherichia coli (E. coli) among poultry-workers. Here determined prevalence and genetic relatedness MDR E. isolated poultry-workers, chickens, poultry...

10.1186/s13756-021-00930-x article EN cc-by Antimicrobial Resistance and Infection Control 2021-03-23

Background Antimicrobial resistance has emerged as a global health threat. resistant Escherichia coli infections are associated with high morbidity and expenditure when compared caused by susceptible strains. In Nigeria, antimicrobial drugs readily available over-the-counter potential for indiscriminate use poultry farmers eventual development of drug resistance. The objective this study was to investigate prevalence risk factors multi-drug E. among workers (PW) in Abuja, Nigeria. Materials...

10.1371/journal.pone.0225379 article EN cc-by PLoS ONE 2019-11-21

Abstract Background Commensal Escherichia coli residing in the guts of humans and animals are reservoirs multidrug resistance (MDR) genes, including quinolone poultry. This study aimed to characterize quinolones E. recovered from poultry workers, chickens, farm/market environments Abuja, Nigeria. Methods was a cross-sectional conducted between December 2018 April 2019 comprising chickens their environments. characterized isolates stool, faecal environmental samples using antimicrobial...

10.1186/s42522-023-00079-0 article EN cc-by One Health Outlook 2023-02-28

Globally, chicken is known to be a reservoir for the spread of antimicrobial resistance genes humans. In Nigeria, drugs are readily accessible use in poultry production, either preventive or therapeutic purposes. Extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-EC) transmissible humans because their zoonotic potentials. People working very closely with chickens on farms markets at greater risk. The aim this study was investigate prevalence and transmission ESBL-EC among...

10.1186/s42522-020-00014-7 article EN cc-by One Health Outlook 2020-05-26

Brucellosis, a neglected debilitating zoonosis, is recognized occupational hazard with high prevalence in developing countries. Transmission to humans can occur through contact infected animals or animal products. Brucellosis presents fever. In Nigeria, there possibility of missed diagnoses by physicians leading long illness. We conducted study determine the seroprevalence and factors associated Human (HB) among abattoir-workers Abuja, Nigeria.We cross-sectional selected using stratified...

10.11604/pamj.2013.16.103.2143 article EN cc-by Pan African Medical Journal 2013-01-01

Nigeria, with a population of over 190 million people, is rated among the 10 countries highest burden infectious and zoonotic diseases globally. In there exist sub-optimal surveillance system to monitor track priority zoonoses. We therefore conducted prioritization for first time in Nigeria guide prevention control efforts. Towards this, two-day in-country consultative meeting involving experts from human, animal, environmental health backgrounds prioritized using modified semi-quantitative...

10.1016/j.onehlt.2021.100257 article EN cc-by-nc-nd One Health 2021-04-28

Cholera, a diarrheal disease caused by the bacterium Vibrio cholerae, transmitted through fecal contamination of water or food remains an ever-present risk in many countries, especially where supply, sanitation, safety, and hygiene are inadequate. A cholera outbreak was reported Bauchi State, North-eastern Nigeria. We investigated to determine extent assess factors associated with outbreak.We conducted descriptive analysis suspected cases fatality rate (CFR), attack (AR), trends/patterns...

10.1186/s12889-023-15332-4 article EN cc-by BMC Public Health 2023-03-07

Antimicrobial resistance (AMR), a global threat driven by factors such as improper antimicrobial use in humans and animals, is projected to cause 10 million annual deaths 2050. For behavior change, public health messages must be tailored for diverse audiences. Generative AI may have the potential create culturally linguistically suited AMR awareness messages. This study assesses ChatGPT-4's capability crafting content. 4 veterinary professionals from linguistic cultural backgrounds...

10.2460/ajvr.24.09.0283 article EN cc-by-nc American Journal of Veterinary Research 2025-01-29

Abstract Background Antimicrobial resistance (AMR) poses a significant threat to global health, particularly in Western sub-Saharan Africa where 27.3 deaths per 100,000 lives are affected, and surveillance control measures often limited. Genomics research plays crucial role understanding the emergence, spread containment of AMR. However, its implementation such settings is challenging due limited human capacity. This manuscript outlines three-day bioinformatics workshop Cameroon,...

10.1186/s12866-025-03865-0 article EN cc-by BMC Microbiology 2025-03-19

Introduction Beef cattle, one of the food-producing animals, are linked to humans through a shared environment and food chain as major source animal protein. Antimicrobial drugs readily accessible for use in production Nigeria. cattle abattoir environments harbor pathogenic bacteria such Escherichia coli ( E. ) which have developed resistance antimicrobial agents used prophylaxis or treatment. This study investigated zoonotic transmission extended-spectrum beta-lactamase-producing (ESBL-EC)...

10.3389/fcimb.2022.869314 article EN cc-by Frontiers in Cellular and Infection Microbiology 2022-04-07

Background Escherichia coli is commonly used as an indicator for antimicrobial resistance (AMR) in food, animal, environment, and human surveillance systems. Our study aimed to characterize AMR E . isolated from retail meat purchased grocery stores North Carolina, USA part of the National Antimicrobial Resistance Monitoring System (NARMS). Materials methods Retail chicken (breast, n = 96; giblets, 24), turkey (n 96), pork 96) products were monthly different counties Carolina during 2022....

10.1371/journal.pone.0294099 article EN cc-by PLoS ONE 2024-01-05

Introduction Salmonella is considered one of the most significant pathogens in public health since it a bacterium that frequently linked to food-borne illnesses humans. Some serovars are responsible for outbreaks connected consumption animal products. Cattle humans through shared environment and food chain as source protein. In Nigeria, antimicrobial medications easily accessible use food-producing animals. Abattoir environments reservoirs foodborne bacteria like non-typhoidal enterica...

10.1371/journal.pone.0296971 article EN cc-by PLoS ONE 2024-01-22

Abstract Background Human Immuno-Deficiency Virus (HIV) remains one of the world’s significant public health challenges. Viral suppression is key indicator for treatment success in People living with HIV (PLHIV). We determined level viral suppression, and its associated factors among PLHIV attending Federal Medical Centre Katsina (FMC Katsina), Nigeria. Methods This retrospective descriptive cross-sectional study was conducted on 913 positive adults enrolled care between January 2009...

10.1186/s12879-021-06722-3 article EN cc-by BMC Infectious Diseases 2021-10-02

Abstract Infections caused by multi-drug resistant Escherichia coli cause significant morbidity and mortality especially in developing countries. In this study, we describe the molecular characteristics of E. isolated from clinical specimens patients’ outcomes. Phenotypic methods were used identification antimicrobial susceptibility testing a tertiary hospital Abuja, Nigeria. Whole genome sequencing was to resistance genes, serotypes, sequence types/clonal complexes, mobile genetic elements....

10.1038/s41598-022-19289-z article EN cc-by Scientific Reports 2022-09-01

In Nigeria, there have been reports of widespread multiple antimicrobial resistance (AMR) amongst Salmonella isolated from poultry. To mitigate the impact mortality associated with on their farms, farmers resort to use antimicrobials without sound diagnostic advice. We conducted this study describe AMR patterns, mechanisms and genetic similarities within some serovars different layer farms.

10.1371/journal.pone.0290754 article EN public-domain PLoS ONE 2023-09-07

In May 2010, lead poisoning (LP) was confirmed among children <5years (U5) in two communities Zamfara state, northwest Nigeria. Following reports of increased childhood deaths Bagega, another community Zamfara, we conducted a survey to investigate the outbreak and recommend appropriate control measures.We cross-sectional Bagega from 23rd August 6th September, 2010. We administered structured questionnaires parents U5 collect information on household participation ore processing activities....

10.11694/pamj.supp.2014.18.1.4264 article EN PubMed 2014-01-01

Antimicrobial resistance (AMR) has recently gained worldwide recognition, as the emergence of multi-drug resistant organisms led to increased mortality and economic burden. This study aimed assess knowledge, attitudes, practices veterinarians towards rational antimicrobial prescribing identify factors influencing use.

10.1186/s42522-021-00058-3 article EN cc-by One Health Outlook 2021-12-01

To determine the seroprevalence of brucellosis among cattle in some local government areas (LGA) northern part Plateau State, Nigeria. Sera obtained from a total 270 randomly selected different herds four LGAs were for Brucellaantibodies using Rose Bengal Plate Test (RBPT). An overall 9.6% (26/270) was obtained. The Brucella antibodies across LGA ranged 0%-37.3% with Riyom and Bassa having lowest highest respectively while Barkin Ladi had no sero-positive cattle. Females higher percentage...

10.1016/s2222-1808(13)60081-x article EN Asian Pacific Journal of Tropical Disease 2013-08-09

Introduction: In May 2010, lead poisoning (LP) was confirmed among children <5years (U5) in two communities Zamfara state, northwest Nigeria. Following reports of increased childhood deaths Bagega, another community Zamfara, we conducted a survey to investigate the outbreak and recommend appropriate control measures.

10.11604/pamj.supp.2014.18.1.4264 article EN cc-by Pan African Medical Journal 2014-01-01

Abstract The increasing occurrence of antimicrobial-resistant Escherichia coli in human and animal population has become a global public health problem that requires immediate intervention. We aimed to investigate prevalence risk factors for faecal carriage drug-resistant E. among slaughterhouse workers. conducted this cross-sectional study 118 apparently healthy workers the largest slaughterhouses Abuja Lagos from July December 2020. was isolated stool samples antimicrobial susceptibility...

10.1038/s41598-021-92819-3 article EN cc-by Scientific Reports 2021-06-25

Introduction: Nigeria is among the countries with high Tuberculosis (TB) burden by global rating signifying relevance of TB surveillance system evaluation in improving performance and capacity existing system. Hence, this was conducted order to determine gaps proffer solution enhance performance.

10.11604/pamj.2020.35.54.21493 article EN cc-by Pan African Medical Journal 2020-02-24

Brucellosis, a neglected tropical food-borne zoonotic disease, has negative impact on both animal and human health as well tremendous socio-economic in developing countries where rural income relies largely livestock breeding dairy products. It is endemic the population Nigeria recognized occupational hazard. This work was done to establish sero-prevalence predisposing factors of food animals Abuja, Brucella infection. Of 376 cattle, 203 sheep 260 goats screened, 21 (5.6%); 19 (9.4%); 51...

10.1186/s13104-017-2827-y article EN cc-by BMC Research Notes 2017-10-10
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