A5016953080- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Diagnosis and treatment of tuberculosis
- Zoonotic diseases and public health
- Brucella: diagnosis, epidemiology, treatment
- Animal Diversity and Health Studies
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Viral Infections and Outbreaks Research
- vaccines and immunoinformatics approaches
- Infectious Diseases and Mycology
- COVID-19 epidemiological studies
- Microbial infections and disease research
- Burkholderia infections and melioidosis
- Bacteriophages and microbial interactions
- Bacillus and Francisella bacterial research
- Poxvirus research and outbreaks
- Child Nutrition and Water Access
- Virology and Viral Diseases
- Helminth infection and control
- Vector-Borne Animal Diseases
- Infectious Diseases and Tuberculosis
- Food composition and properties
- Pneumocystis jirovecii pneumonia detection and treatment
- Disaster Response and Management
University of Ibadan
2015-2024
Nigerian Institute of Medical Research
2024
General Department of Preventive Medicine
2021
National Public Health Institute of Liberia
2020
Armauer Hansen Research Institute
2012
Makerere University
2012
Stellenbosch University
2012
To establish a molecular epidemiological baseline for the strains causing tuberculosis in Nigeria, survey of isolates from humans and cattle was carried out. Spoligotyping variable-number tandem-repeat analysis revealed that majority disease Ibadan, southwestern is caused by single, closely related group Mycobacterium strains. Using deletion typing, we show approximately 13% this sample africanum bovis rather than M. tuberculosis. Molecular recovered Nigerian they form similarity to...
Despite slow reductions in the annual burden of active human tuberculosis (TB) cases, zoonotic TB (zTB) remains a poorly monitored and an important unaddressed global problem. There is higher incidence some regions countries, especially where close association exists between growing numbers cattle (the major source Mycobacterium bovis) people, many suffering from poverty, dairy products are consumed unpasteurised. More attention needs to be focused on possible increased zTB resulting growth...
Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a severe animal and human disease. Recently, group taxonomists merged brucellae with primarily free-living, phylogenetically related
We have identified a clonal complex of Mycobacterium bovis present at high frequency in cattle population samples from several sub-Saharan west-central African countries. This closely related group bacteria is defined by specific chromosomal deletion (RDAf1) and can be the absence spacer 30 standard spoligotype typing scheme. named this strains 1 (Af1) signature as being same M. BCG vaccine strain but with 30. Strains Af1 were found Mali, Cameroon, Nigeria, Chad, using combination...
ABSTRACT We have identified a clonal complex of Mycobacterium bovis isolated at high frequency from cattle in Uganda, Burundi, Tanzania, and Ethiopia. named this related group M. strains the African 2 (Af2) bovis. Af2 are defined by specific chromosomal deletion (RDAf2) can be absence spacers 3 to 7 their spoligotype patterns. Deletion analysis isolates Algeria, Mali, Chad, Nigeria, Cameroon, South Africa, Mozambique did not identify any complex, suggesting that is localized East Africa. The...
A serological survey of brucellosis in livestock animals and workers wasconducted Ibadan, Southwestern Nigeria between May August 2004. Atotal 1,210 cattle, 54 sheep, 496 goats, 200 pigs 21 humans (i.e. butchers herdsmen) were screened using the Rose Bengal test (RBT).From results, prevalence trade cattle was 5.82% while 0.86% recorded goats. None sheep positive to test. Out 11 samples taken from butchers, seven none ten herdsmen sero-positive. This gives an infection rate 63.3% butchers; a...
Nigeria, with a population of over 190 million people, is rated among the 10 countries highest burden infectious and zoonotic diseases globally. In there exist sub-optimal surveillance system to monitor track priority zoonoses. We therefore conducted prioritization for first time in Nigeria guide prevention control efforts. Towards this, two-day in-country consultative meeting involving experts from human, animal, environmental health backgrounds prioritized using modified semi-quantitative...
Brucellosis is an endemic disease in the animal population Nigeria and of major public health importance, particularly amongst livestock workers who are ignorant risk Brucella infection. Therefore, to gain insight into knowledge practices related brucellosis transmission holders (LH) marketers (LM) Yewa, international trading centre south-western Nigeria, we conducted interviewbased study using a cluster sampling technique. In all, total 157 respondents comprising 54 LH 103 LM were...
As part of an ongoing project to investigate the epidemiology gastrointestinal helminths cattle in Nigeria, we carried out a systematic random sampling slaughtered major abattoir Ibadan, south-western Nigeria. Using sedimentation and floatation methods, analyzed fecal samples from 397 animals between March May 2013. Overall, 163 (41.6%) had at least one helminth egg, comprising total eight different genera (i.e., four nematodes, three trematodes, cestode), with nematode infection being...
A retrospective study was conducted to investigate the prevalence of bovine tuberculosis and direct economic losses (DEL) from in cattle slaughtered Makurdi abattoirs 2008 2012, using abattoir records obtained Ministry Agriculture Natural Resources. Out 61654 during period 1172 (1.90%) were positive for lesions. The annual ranges 0.90% 4.04% 2012. There significant (P < 0.05) difference tuberculosis. It also observed that there no seasonal total 1935 affected organs by BTB weighing 3046.50...
Bovine brucellosis is endemic in Nigeria; however, limited data exist on nationwide studies and risk factors associated with the disease. Using a cross-sectional sero-epidemiological survey, we determined prevalence of for slaughtered cattle three geographical regions Nigeria. Serum samples from randomly selected unvaccinated over period 3 years (between December 2010 September 2013) northern, southern south-western Nigeria were tested antibodies to Brucella abortus using Rose Bengal test....
Tuberculosis remains a major public health challenge globally with increasing risks for inter-transmission between pastoralists and cattle in Nigeria. This study was aimed at using molecular tools to establish zoonotic transmission of tuberculosis their Ebonyi State, Sputum (n = 149) milk 144) samples from cattle, respectively were screened on the assumption subclinical infections considering unguarded human-livestock interactions. Isolates obtained analysed deletion typing, spoligotyping...
Lassa fever (LF) is prevalent in many West African countries, including Nigeria. Efforts to combat LF have primarily focused on rural areas where interactions between rodents and humans are common. However, recent studies indicate a shift its occurrence from urban areas. We analysed secondary data of reported outbreaks 2017 2021 Ondo State, Nigeria identify the distribution pattern, ecological variations, other determinants disease spread ward level using nearest neighbour statistics...
In this study, milk and blood samples collected simultaneously from 532 trade cows to be slaughtered at Bodija abattoir, Ibadan (southwestern, Nigeria) were examined for antibodies Brucella using the ring test (MRT) rose bengal (RBT). Overall, 18.61% of positive according MRT, while 9.77% serum RBT. The difference was highly significant (Chi-square value 16.33; P < 0.05); only 32 (6.02%) both tests. Red Bororo breed cattle White Fulani had highest rates, namely 20.93% 11.69% MRT RBT...
Bovine tuberculosis (TB) is endemic in the cattle population Nigeria. Livestock workers are at risk of Mycobacterium bovis infection and unaware their health status.To determine occurrence pulmonary M. among livestock workers.A cross-sectional study traders was conducted for TB through screening sputum samples using a simple random sampling method coupled with oral interview on assumption sub-clinical infection. Specimens were cultured, isolates analysed molecular typing techniques.Overall,...