Raquel Martínez-Méndez

ORCID: 0000-0003-4219-8003
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About
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Research Areas
  • Vibrio bacteria research studies
  • Bacterial biofilms and quorum sensing
  • Genetics, Aging, and Longevity in Model Organisms
  • Photoreceptor and optogenetics research
  • Photosynthetic Processes and Mechanisms
  • Circadian rhythm and melatonin
  • CRISPR and Genetic Engineering
  • Biochemical effects in animals
  • Antibiotic Resistance in Bacteria
  • Light effects on plants
  • Retinal Development and Disorders
  • Epigenetics and DNA Methylation
  • Sleep and Wakefulness Research
  • Metabolism and Genetic Disorders
  • Legionella and Acanthamoeba research
  • Polyamine Metabolism and Applications
  • Lipid Membrane Structure and Behavior
  • Cephalopods and Marine Biology
  • Neural dynamics and brain function
  • Marine animal studies overview
  • Neuroscience and Neural Engineering
  • Turtle Biology and Conservation
  • Genomics and Chromatin Dynamics

Universidad Nacional Autónoma de México
2009-2024

Universidad Autónoma del Estado de Morelos
2021-2023

University of California, Santa Cruz
2020-2021

Abstract The auxin-inducible degron (AID) system has emerged as a powerful tool to conditionally deplete proteins in range of organisms and cell types. Here, we describe toolkit augment the use AID Caenorhabditis elegans. We have generated set single-copy, tissue-specific (germline, intestine, neuron, muscle, pharynx, hypodermis, seam cell, anchor cell) pan-somatic TIR1-expressing strains carrying co-expressed blue fluorescent reporter enable both red green channels experiments. These...

10.1093/genetics/iyab006 article EN cc-by Genetics 2021-01-20

c-di-GMP trigger phosphodiesterases (PDEs) could play a key role in controlling the heterogeneity of biofilm matrix composition, property that endows characteristics are potentially relevant for sustaining integrity and functionality biofilms variety natural environments. Trigger PDEs not always easy to identify based on their sequence, hence many examples these type signaling proteins have been reported literature.

10.1128/jb.00046-21 article EN Journal of Bacteriology 2021-04-13

In sexually reproducing metazoans, spermatogenesis is the process by which uncommitted germ cells give rise to haploid sperm. Work in model systems has revealed mechanisms controlling commitment sperm fate, but how this fate subsequently executed remains less clear. While studying well-established role of conserved nuclear hormone receptor transcription factor, NHR-23/NR1F1, regulating C. elegans molting, we discovered that NHR-23/NR1F1 also constitutively expressed developing primary...

10.1242/dev.193862 article EN publisher-specific-oa Development 2020-01-01

The second messenger cyclic dimeric GMP (c-di-GMP) plays a central role in controlling decision-making processes that are vitally important for the environmental survival of human pathogen Vibrio parahaemolyticus. mechanisms by which c-di-GMP levels and biofilm formation dynamically controlled V. parahaemolyticus poorly understood. Here, we report involvement OpaR metabolism its effects on expression trigger phosphodiesterase (PDE) TpdA biofilm-matrix related gene cpsA. Our results revealed...

10.1128/spectrum.00872-23 article EN cc-by Microbiology Spectrum 2023-05-18

Abstract The auxin-inducible degron (AID) system has emerged as a powerful tool to conditionally deplete proteins in range of organisms and cell-types. Here, we describe toolkit augment the use AID Caenorhabditis elegans . We have generated set single-copy, tissue-specific (germline, intestine, neuron, muscle, hypodermis, seam cell, anchor cell) pan-somatic TIR1- expressing strains carrying an equimolar co-expressed blue fluorescent reporter enable both red green channels experiments. also...

10.1101/2020.05.12.090217 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2020-05-13

The ability of sea turtle hatchlings to find the seashore soon after hatching is thought be exclusively dependent upon visual information. Target-oriented movements in most vertebrates, however, relay on combining information gathered through different sensory systems. Hence, this work, we investigated whether olfactory and/or magnetic might complement cues during hatchling’s seaward crawling. Acute deprivation and distorted sensation visually competent resulted a scattering crawling routes...

10.4236/abb.2011.22008 article EN Advances in Bioscience and Biotechnology 2011-01-01

Neonatal eye loss leads to an expansion of the primary somatosensory cortex (S1) in rodents. In blind rats, S1 results from predisplacement formation during first three days life, a process modulated by epigenetic factors. Some these factors might be local and some others may come extra-S1 sources such as cerebrospinal fluid (CSF). Thus, we evaluated concentration glutamate, GABA serotonin CSF control birth-enucleated rat pups. These neurotransmitters modulate through mechanisms several...

10.7287/peerj.preprints.1782v1 preprint EN 2016-02-25

ABSTRACT Ornithine lipids (OLs) are phosphorus-free membrane that can be formed by a wide range of bacteria. The presence OLs is frequently related to the resistance abiotic stress conditions, and its synthesis often induced as part various responses. Two different pathways for synthesizing currently known: OlsBA pathway first described in Sinorhizobium meliloti , OlsF Serratia proteamaculans . We identified genome Vibrio cholerae O1 El Tor A1552 two genes encoding homologs, VC0489 located...

10.1101/2024.12.11.627999 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2024-12-11

Bilateral eye enucleation at birth (BE) leads to an expansion of the primary somatosensory cortex (S1) in rat pups. Although increased growth thalamo-cortical afferents (STCAs) part explains S1 expansion, timing mechanisms governing formation are also involved. In this work, we begin search a developmental clock by intending document existence putative neurons thalamus (VPM) and based upon changes spontaneous spike amplitude; biophysical property sensitive circadian regulation; latter known...

10.1016/j.ibror.2019.11.003 article EN cc-by-nc-nd IBRO Reports 2019-11-10

Abstract In sexually reproducing metazoans, spermatogenesis is the process by which uncommitted germ cells give rise to haploid sperm. Work in model systems has revealed mechanisms controlling commitment sperm fate, but how this fate subsequently executed remains less clear. While studying well-established role of conserved nuclear hormone receptor transcription factor, NHR-23/NR1F1, regulation C. elegans molting, we discovered NHR-23/NR1F1 also constitutively expressed developing 1°...

10.1101/2020.06.11.147298 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2020-06-12

Neonatal eye loss leads to an expansion of the primary somatosensory cortex (S1) in rodents. In blind rats, S1 results from predisplacement formation during first three days life, a process modulated by epigenetic factors. Some these factors might be local and some others may come extra-S1 sources such as cerebrospinal fluid (CSF). Thus, we evaluated concentration glutamate, GABA serotonin CSF control birth-enucleated rat pups. These neurotransmitters modulate through mechanisms several...

10.7287/peerj.preprints.1782 preprint EN 2016-02-25

It has been long thought that the brain reorganizes itself in response to environmental needs. Sensory experiences coded action potentials are mean by which information on surroundings is introduced into neuronal networks. The approaching form of electrochemical codes must then be translated biochemical, epigenetic and genetic ones. Only until recently we have begun understanding underpinning such informational transformations how this process expressed as plastic responses. Central for our...

10.5016/1806-8774.2009v11pt114 article EN Annual Review of Biomedical Sciences 2009-03-04

Abstract The second messenger cyclic dimeric guanosine monophosphate (c-di-GMP) plays a central role in controlling decision making processes of vital importance for the environmental survival human pathogen Vibrio parahaemolyticus . mechanisms by which c-di-GMP levels are dynamically controlled V. poorly understood. Here we report our findings regarding involvement OpaR metabolism planktonic and surface-attached cells through expression trigger phosphodiesterase (PDE) TpdA other PDEs such...

10.1101/2023.01.10.523516 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-01-13

Abstract Vibrio parahaemolyticus cells transit from free swimming to surface adapted lifestyles, such as swarming colonies and three-dimensional biofilms. These transitions are regulated by sensory modules regulatory networks that involve the second messenger cyclic dimeric guanosine monophosphate (c-di-GMP). In this work, we show a previously uncharacterized c-di-GMP phosphodiesterase (VP1881) V. plays an important role in modulating pool. We found product of VP1881 promotes its own...

10.1101/2021.01.26.428358 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-01-28
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