A5015971130- Drug Transport and Resistance Mechanisms
- Cancer, Lipids, and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Nanoplatforms for cancer theranostics
- Extracellular vesicles in disease
- Nanoparticle-Based Drug Delivery
- Molecular Biology Techniques and Applications
Shantou University
2020-2023
Cancer Hospital of Shantou University Medical College
2020-2023
Shantou Central Hospital
2020
First Affiliated Hospital of Shantou University Medical College
2020
Shantou University Medical College
2020
Trastuzumab (Tmab) targeted therapy or its combination with chemotherapy is normally insufficient to elicit a comprehensive therapeutic response owing the inherent acquired drug resistance and systemic toxicity observed in highly invasive HER2-positive breast cancer. In this study, we propose novel approach that integrates photothermal (PTT) chemotherapy, thereby achieving additive synergistic outcomes. We utilize PEGylated two-dimensional black phosphorus (2D BP) as nanoplatform agent load...
Abstract Background Early prediction of response to neoadjuvant chemotherapy (NAC) is critical in choosing appropriate chemotherapeutic regimen for patients with locally advanced breast cancer. Herein, we sought identify potential biomarkers that could predict the cancer patients. Methods Three genomic profiles acquired by polymerase chain reaction (PCR) from subjects or without residual tumors after NAC downloaded GEO database were used screen differentially expressed genes (DEGs). An array...
Abstract Background: Early prediction of response to neoadjuvant chemotherapy (NAC) is critical in choosing appropriate chemotherapeutic regimen for patients with locally advanced breast cancer. Herein, we sought identify potential biomarkers predict the cancer patients. Methods: Three genomic profiles acquired by microarray analysis from subjects or without residual tumors after NAC downloaded GEO database were used screen differentially expressed genes (DEGs). An array public databases,...