A5035539008- Cancer, Lipids, and Metabolism
- Osteoarthritis Treatment and Mechanisms
- Inflammatory mediators and NSAID effects
- Drug Transport and Resistance Mechanisms
- MicroRNA in disease regulation
- Nerve injury and regeneration
- RNA Interference and Gene Delivery
- Periodontal Regeneration and Treatments
- Graphene and Nanomaterials Applications
- Extracellular vesicles in disease
- Molecular Biology Techniques and Applications
- PI3K/AKT/mTOR signaling in cancer
- Mesenchymal stem cell research
- Peroxisome Proliferator-Activated Receptors
- Viral Infections and Immunology Research
- Escherichia coli research studies
- CRISPR and Genetic Engineering
- Nerve Injury and Rehabilitation
- Transportation and Mobility Innovations
- Peripheral Nerve Disorders
- Ferroptosis and cancer prognosis
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Circular RNAs in diseases
- Carbon and Quantum Dots Applications
Shantou University
2020-2025
Shantou University Medical College
2020-2025
Peking University Shenzhen Hospital
2023-2025
Shenzhen University
2025
Southwest Jiaotong University
2023
Carolinas Healthcare System
2016
Texas Oncology
2016
Memorial Sloan Kettering Cancer Center
2016
The chemokine CXCL9 (C-X-C motif ligand 9) has been reported to be required for antitumour immune responses following checkpoint blockade. In this study, we sought investigate the potential value of according in patients with breast cancer (BC). A variety open-source databases and online tools were used explore expression features prognostic significance BC its correlation immune-related biomarkers followed by subsequent verification immunohistochemistry experiments. mRNA level was found...
Abstract Osteoarthritis (OA) is a degenerative disease caused by variety of factors with joint pain as the main symptom, including fibrosis, chapping, ulcers, and loss cartilage. Traditional treatment can only delay progression OA, classical delivery system have many side effects. In recent years, microspheres shown great application prospects in field OA treatment. Microspheres support cells, reproduce natural tissue microenvironment vitro vivo, are an efficient for release drugs or...
Abstract Osteoarthritis (OA), known as one of the most common types aseptic inflammation musculoskeletal system, is characterized by chronic pain and whole-joint lesions. With cellular molecular changes including senescence, inflammatory alterations, subsequent cartilage defects, OA eventually leads to a series adverse outcomes such disability. CRISPR-Cas-related technology has been proposed explored gene therapy, offering potential gene-editing tools that are in spotlight. Considering...
Osteoporotic fractures are induced by osteoporosis, which may lead to the degradation of bone tissues and microstructures impair their healing ability. Conventional internal fixation therapies ineffective in treatment osteoporotic fractures. Hence, developing tissue engineering materials is crucial for repairing It has been demonstrated that nanomaterials, particularly graphene oxide (GO), possess unique advantages due excellent biocompatibility, mechanical properties, osteoinductive...
Early prediction of response to neoadjuvant chemotherapy (NAC) is critical in choosing appropriate chemotherapeutic regimen for patients with locally advanced breast cancer. Herein, we sought identify potential biomarkers predict the cancer patients.Three genomic profiles acquired by microarray analysis from subjects or without residual tumors after NAC downloaded GEO database were used screen differentially expressed genes (DEGs). An array public databases, including ONCOMINE, cBioportal,...
CREC represents a public health threat worldwide, and its colonization precedes or occurs simultaneously with infection; once the rate increases, infection rises sharply. In our hospital, of remained low, almost all isolates detected were ICU acquired.
With the increasing penetration of electric vehicles (EV) and distributed generations (DG) in distribution networks, operation control networks (DN) is faced with many new challenges. Considering remarkable characteristics network layered by voltage level spatial temporal EV charging load, a hierarchical optimization method for DN proposed. Firstly, prediction model load established, which composed three parts: resident travel probability model, vehicle mobility traffic model. Secondly,...
Abstract Purpose: This study aims to elucidate emerging trends, dynamic advancements, and research focal points in exosome-mediated repair regeneration of cartilage damage over the past decade, employing a visualization approach. Methods: A total 300 records focusing on utilization exosomes were systematically gathered from Web Science Core Collection (WoSCC) database spanning years 2013 2023. Utilizing R language, VOSviewer, CiteSpace, GraphpadPrism software, we conducted analyses general...
Abstract Background: TNBC often exhibits activation of PI3K/Akt signaling, associated with loss PTEN expression, low INPP4B and/or increased AKT3 amplification. Inhibition the pathway in diverse cancers leads to radiosensitization chemosensitization. Ipat is an oral, potent ATP-competitive small molecule inhibitor all three isoforms Akt. The combination ipat taxanes preclinical models resulted enhanced efficacy relative either or chemotherapy alone. In a Phase Ib clinical study, regimens was...
Abstract Background Early prediction of response to neoadjuvant chemotherapy (NAC) is critical in choosing appropriate chemotherapeutic regimen for patients with locally advanced breast cancer. Herein, we sought identify potential biomarkers that could predict the cancer patients. Methods Three genomic profiles acquired by polymerase chain reaction (PCR) from subjects or without residual tumors after NAC downloaded GEO database were used screen differentially expressed genes (DEGs). An array...
Peripheral nerve defect is a difficult disease to treat in clinical practice. End-to-side anastomosis useful method it. At present, the end-to-side does not involve proximal nerve, which results waste of donor nerves, and even formation traumatic neuromas at end. The patients suffer from neuralgia curative effect unsatisfactory.In this study, an improved technique was proposed study: both distal ends damaged common peroneal were sutured adjacent normal tibial nerve. Moreover, possible role...
Abstract Background: Early prediction of response to neoadjuvant chemotherapy (NAC) is critical in choosing appropriate chemotherapeutic regimen for patients with locally advanced breast cancer. Herein, we sought identify potential biomarkers predict the cancer patients. Methods: Three genomic profiles acquired by microarray analysis from subjects or without residual tumors after NAC downloaded GEO database were used screen differentially expressed genes (DEGs). An array public databases,...
Abstract Background: Early prediction of response to neoadjuvant chemotherapy (NAC) is critical in choosing appropriate chemotherapeutic regimen for patients with locally advanced breast cancer. Herein, we sought identify potential biomarkers predict the cancer patients. Methods: Three genomic profiles acquired by microarray analysis from subjects or without residual tumors after NAC downloaded GEO database were used screen differentially expressed genes (DEGs). An array public databases,...