Linghong Zhang

ORCID: 0000-0001-9705-2920
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About
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Research Areas
  • Advancements in Battery Materials
  • Antibiotic Resistance in Bacteria
  • Advanced Battery Technologies Research
  • Advanced Battery Materials and Technologies
  • Vibrio bacteria research studies
  • Radical Photochemical Reactions
  • Fluorine in Organic Chemistry
  • Antibiotics Pharmacokinetics and Efficacy
  • Subcritical and Supercritical Water Processes
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Extraction and Separation Processes
  • Salmonella and Campylobacter epidemiology
  • Environmental remediation with nanomaterials
  • Semiconductor materials and devices
  • Bacterial biofilms and quorum sensing
  • Plant Pathogenic Bacteria Studies
  • Thermochemical Biomass Conversion Processes
  • Infections and bacterial resistance
  • Escherichia coli research studies
  • Oxidative Organic Chemistry Reactions
  • Tissue Engineering and Regenerative Medicine
  • Bacterial Identification and Susceptibility Testing
  • Catalysts for Methane Reforming
  • Bacteriophages and microbial interactions
  • Energy Load and Power Forecasting

Zhejiang University
2019-2025

Sir Run Run Shaw Hospital
2019-2025

Henan University
2023-2024

Sichuan University
2022-2024

Henan Normal University
2024

Zhejiang University of Technology
2024

State Key Laboratory of Biotherapy
2022-2023

Argonne National Laboratory
2017-2023

Shantou University
2023

A123 Systems (United States)
2021-2022

Myocardial infarction (MI) leads to massive cardiomyocyte death and deposition of collagen fibers. This fibrous tissue disrupts electrical signaling in the myocardium, leading cardiac systolic diastolic dysfunction, as well arrhythmias. Conductive hydrogels are a promising therapeutic strategy for MI. Here, we prepared highly water-soluble conductive material (GP) by grafting polypyrrole (PPy) onto non-conductive gelatin. component was added gel system formed Schiff base reaction between...

10.1016/j.bioactmat.2022.06.001 article EN cc-by-nc-nd Bioactive Materials 2022-06-13

An epoxy group was successfully attached to the surface of silicon nanoparticle (SiNPs) via a silanization reaction between silanol-enriched SiNPs and functional silanes. The epoxy-functionalized showed much improved cell performance compared with pristine because increased stability electrolyte formation covalent bond polyacrylic acid binder. Furthermore, anode laminate made from epoxy-SiNPs enhanced adhesion strength. Post-test analysis shed light on how epoxy-functional affects physical...

10.1021/acsami.8b17729 article EN ACS Applied Materials & Interfaces 2018-11-28

Myocardial infarction (MI) causes irreversible damage to the heart muscle, seriously threatening lives of patients. Injectable hydrogels have attracted extensive attention in treatment MI. By promoting coupling mechanical and electrical signals between cardiomyocytes, combined with synergistic therapeutic strategies targeting pathological processes inflammation, proliferation, fibrotic remodeling after MI, it is expected improve effect. In this study, a pH/ROS dual-responsive injectable...

10.1016/j.bioactmat.2023.07.007 article EN cc-by-nc-nd Bioactive Materials 2023-07-12

Abstract Bone defects in osteoporosis usually present excessive reactive oxygen species (ROS), abnormal inflammation levels, irregular shapes and impaired bone regeneration ability; therefore, osteoporotic are difficult to repair. In this study, an injectable thermosensitive hydrogel poly (D, L‐lactide)‐poly (ethylene glycol)‐ L‐lactide) (PLEL) system containing resveratrol (Res) dexamethasone (DEX) is designed create a microenvironment conducive osteogenesis defects. This PLEL injected...

10.1002/smtd.202300843 article EN Small Methods 2023-10-06

BackgroundCarbapenem-resistant Acinetobacter baumannii (CRAB) is a major public health concern globally. Often studied in the context of hospital outbreaks, little known about persistence and evolutionary dynamics endemic CRAB populations.MethodsA three-month cross-sectional observational study was conducted 28-bed intensive care unit (ICU) Hangzhou, China. A total 5068 samples were collected from environment (n = 3985), patients 964) staff 119). isolates obtained 10.5% these 532). All...

10.1016/j.lanwpc.2023.100780 article EN cc-by The Lancet Regional Health - Western Pacific 2023-05-09

Asymmetric olefin isomerization can be appreciated as an ideal synthetic approach to access valuable enantioenriched C═C-containing molecules due the excellent atom economy. Nonetheless, its occurrence usually requires a thermodynamic advantage, namely, higher stability of product substrate. It has thus led rather limited examples success. Herein, we report photoredox catalytic hydrogen transfer (HAT) and enantioselective protonation strategy for challenging asymmetric isomerization. As...

10.1021/jacs.3c03732 article EN Journal of the American Chemical Society 2023-08-08

Klebsiella pneumoniae carbapenemase (KPC)-producing Pseudomonas aeruginosa (KPC-PA) has been reported sporadically. However, epidemiological and antimicrobial susceptibility data specific for KPC-PA are lacking. We collected 374 carbapenem-resistant P. (CRPA) isolates from seven hospitals in China June 2016 to February 2019 identified the blaKPC-2 gene 40.4% (n = 151/374) of isolates. Approximately one-half all 76/151; 50.3%) were resistant ceftazidime-avibactam (CAZ-AVI). Combining Kraken2...

10.1128/msystems.00787-21 article EN mSystems 2021-11-02

To characterize a blaOXA-58- and blaNDM-1-containing MDR plasmid from rare Acinetobacter baumannii lineage compare it with related plasmids to explore the distribution evolution of new group.A. DETAB-P2 was isolated rectal swab an intensive care patient. Antibiotic susceptibility determined using broth microdilution. mated A. ATCC 17978 putative transconjugants were characterized by S1/PFGE Southern hybridization. WGS performed on Illumina Oxford Nanopore platforms. MLST Pasteur schemes....

10.1093/jac/dkab005 article EN Journal of Antimicrobial Chemotherapy 2021-01-13

ObjectivesCommunity onset urinary tract infections (COUTIs) drew attention recently owing to their increased prevalence and associations with resistant pathogens. The study is aimed at investigating the etiology of COUTIs as well related risk factors extended-spectrum β-lactamase (ESBL) in China.MethodsThe prospective was performed nineteen hospitals during November 1, 2017 August 31, 2019. Non-duplicated isolates from were included. ESBL phenotypic confirmation test whole genomes sequenced...

10.1016/j.jinf.2021.06.004 article EN cc-by-nc-nd Journal of Infection 2021-06-09

Na2 Ti6 O13 (NTO) with high safety has been regarded as a promising anode candidate for sodium-ion batteries. In the present study, integrated modification of migration channels broadening, charge density re-distribution, and oxygen vacancies regulation are realized in case Nb-doping have obtained significantly enhanced cycling performance 92 % reversible capacity retained after 3000 cycles at mA g-1 . Moreover, unexpected low-temperature discharge 143 mAh 100 under -15 °C is also achieved...

10.1002/anie.202312310 article EN Angewandte Chemie International Edition 2023-10-05

Acinetobacter species have emerged as a significant public health concern due to their remarkable capacity acquire antimicrobial resistance. Environmental reservoirs play crucial role in spreading resistance genes and potentially pathogenic bacteria clinical settings. However, most studies on nonhuman isolates focused limited sample size. Comprehensive population sampling One Health principles is essential monitor the antibiotic resistome virulome spp. Here, we identified three...

10.1016/j.envint.2025.109373 article EN cc-by-nc-nd Environment International 2025-03-12

The effects of aliphatic sugar alcohols (e.g., threitol, xylitol, sorbitol) on the hydration tricalcium silicate (C 3 S) and ordinary portland cement (OPC) were investigated compared with those sucrose, a well‐established set retarder. Only which contain threo diol functionality retarded setting C S OPC, their efficacy increasing number hydroxy pairs and, to smaller extent, overall population groups. None, however, as effective sucrose. initial final times increased exponentially...

10.1111/j.1551-2916.2009.03378.x article EN Journal of the American Ceramic Society 2009-10-29

Acinetobacter baumannii is an important pathogen in hospital acquired infections. Although tigecycline currently remains a potent antibiotic for treating infections caused by multidrug resistant A. (MDRAB) strains, reports of isolates have substantially increased. The resistance mechanisms to are far more complicated and diverse than what has been described the literature so far. Here, we characterize vitro-selected MDRAB strains obtained increasing concentrations tigecycline. We identified...

10.1080/22221751.2021.1948804 article EN cc-by-nc Emerging Microbes & Infections 2021-01-01

The occurrence of carbapenemase-producing Proteus mirabilis , especially those strains producing NDM-1 and its variants, is a major public health concern worldwide. integrative conjugative element (ICE) plays an important role in horizontal acquisition resistance genes.

10.1128/msphere.00588-21 article EN cc-by mSphere 2021-08-11
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