A5056946309- Bone Tissue Engineering Materials
- biodegradable polymer synthesis and properties
- Radiation Detection and Scintillator Technologies
- Graphene and Nanomaterials Applications
- 3D Printing in Biomedical Research
- Nuclear Physics and Applications
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Nuclear reactor physics and engineering
- Hydrogels: synthesis, properties, applications
- Additive Manufacturing and 3D Printing Technologies
- Dental materials and restorations
- Advanced Photocatalysis Techniques
- Wound Healing and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Bone Metabolism and Diseases
- Dental Implant Techniques and Outcomes
- Geophysical Methods and Applications
- Cerebrovascular and Carotid Artery Diseases
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Moyamoya disease diagnosis and treatment
- Dendrimers and Hyperbranched Polymers
- Connective tissue disorders research
- Architecture, Modernity, and Design
Chengdu University
2022-2025
Sichuan University
2023-2025
State Key Laboratory of Biotherapy
2023-2025
Southwest University of Science and Technology
2022-2023
Chengdu Medical College
2023
Chengdu Organic Chemicals (China)
2019-2021
Chinese Academy of Sciences
2019-2021
University of Chinese Academy of Sciences
2019-2021
Abstract Methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infection, caused by impaired glucose metabolism in diabetic foot patients, poses a significant obstacle to the healing process and carries high risk of being life‐threatening. Due microvascular occlusion entrenchment MRSA biofilms foot, controlling effectively treating infection remains challenging. Traditional hydrogels suffer from swelling‐related mechanical issues inadequate drug release control, limiting their...
Osteomyelitis is a devastating disease caused by microbial infection in deep bone tissue. Its high recurrence rate and impaired restoration of deficiencies are major challenges treatment. Microbes have evolved numerous mechanisms to effectively evade host intrinsic adaptive immune attacks persistently localize the host, such as drug-resistant bacteria, biofilms, persister cells, intracellular small colony variants (SCVs). Moreover, microbial-mediated dysregulation microenvironment impedes...
Abstract Infected bone defects are one of the most challenging problems in treatment due to high antibiotic failure rate and lack ideal grafts. In this paper, inspired by clinical cement filling treatment, α ‐c phosphate ( ‐TCP) with self‐curing properties is composited β ‐tricalcium constructed a bionic cancellous scaffolding system α/β‐tricalcium / low‐temperature 3D printing, gelatin preserved inside scaffolds as an organic phase, later loaded metal–polyphenol network structure tea...
3D-printing scaffold with specifically customized and biomimetic structures gained significant recent attention in tissue engineering for the regeneration of damaged bone tissues. However, constructed scaffolds that simultaneously promote situ inhibit bacterial proliferation remains a great challenge. This study aimed to design repair antibacterial functions.Herein, general strategy is developed by using epigallocatechin-3-gallate (EGCG), major green tea polyphenol, firmly anchored...
Abstract Bone defects in osteoporosis usually present excessive reactive oxygen species (ROS), abnormal inflammation levels, irregular shapes and impaired bone regeneration ability; therefore, osteoporotic are difficult to repair. In this study, an injectable thermosensitive hydrogel poly (D, L‐lactide)‐poly (ethylene glycol)‐ L‐lactide) (PLEL) system containing resveratrol (Res) dexamethasone (DEX) is designed create a microenvironment conducive osteogenesis defects. This PLEL injected...
Abstract Large size bone defects have become a growing clinical challenge. Cancellous bone, which has the highest volume ratio, fastest replacement rate, and interconnected porous structure, plays major role in repairing. Considering structure composition of cancellous building bionic 3D scaffold via customized‐3D printing technology is key to solving problem. As earliest degradable medical polymer material approved by Food Drug Administration, polylactic acid been proved excellent biosafety...
Abstract Postoperative adhesions are inevitable consequences of surgery, resulting in various complications. The risk increases, particularly cardiac where reoperations or staged operations high demand. presence severely complicates resternotomy procedures, which may increase the re‐traumatizing, bleeding, operation time extension, and even mortality. Here, a biodegradable thermo‐sensitive fouling‐resistant hydrogel based on poly(D,L‐lactide)/poly(ethylene glycol) (PLEL) micelles is...
Abstract Pelvic inflammatory disease (PID) is a critical global health concern with the potential to lead adverse outcomes, including infertility and chronic pelvic pain. Since PID often caused by ascending vaginal infections or urinary tract infections, understanding treatment of both preventing PID. Meanwhile, emergence drug‐resistant persistently infected strains poses growing challenge. This review discusses current clinical treatments for prevention from physiologic basis PID, as well...
Nowadays, mobile robots have been used to search for uncontrolled radioactive source in indoor environments avoid radiation exposure technicians. However, the environments, especially presence of obstacles, how make with limited sensing capabilities automatically remains a major challenge. Also, efficiency needs be further improved meet practical scenarios such as exploration time. This paper proposes an automatic strategy, abbreviated ACA: location is estimated by convolutional neural...
In recent years, unmanned ground vehicles (UGVs) have been used to search for lost or stolen radioactive sources avoid radiation exposure operators. To achieve autonomous localization of sources, the UGVs must ability automatically determine next measurement location instead following a predefined path. Also, field has be reconstructed inverted utilizing discrete measurements obtain intensity distribution in area interest. this study, we propose an effective source framework and method,...