A5102899722- Soil Carbon and Nitrogen Dynamics
- Ecology and Vegetation Dynamics Studies
- Plant Water Relations and Carbon Dynamics
- Peatlands and Wetlands Ecology
- Ruminant Nutrition and Digestive Physiology
- Gut microbiota and health
- Rangeland Management and Livestock Ecology
- Plant and animal studies
- Microbial Community Ecology and Physiology
- Soil and Unsaturated Flow
- Mycorrhizal Fungi and Plant Interactions
- Climate change and permafrost
- Atmospheric and Environmental Gas Dynamics
- Soil and Water Nutrient Dynamics
- Genomics and Phylogenetic Studies
- Climate variability and models
- Soil erosion and sediment transport
- Cervical Cancer and HPV Research
- Land Use and Ecosystem Services
- Metabolomics and Mass Spectrometry Studies
- Virus-based gene therapy research
- Reproductive Physiology in Livestock
- Immune Response and Inflammation
- Geology and Paleoclimatology Research
- Cancer-related molecular mechanisms research
Nanjing Tech University
2025
Institute of Geographic Sciences and Natural Resources Research
2020-2025
Chinese Academy of Sciences
2020-2025
Capital Medical University
2024
Chinese University of Hong Kong
2024
Shenyang Agricultural University
2017-2024
Hohai University
2024
Chinese PLA General Hospital
2024
University of Chinese Academy of Sciences
2021-2023
Shanghai Jiao Tong University
2018-2023
Hepatitis B virus (HBV) RNA in serum has recently been linked to efficacy and prognosis of chronic hepatitis (CHB) treatment. This study explored the nature, origin, underlying mechanisms, potential clinical significance HBV RNA.The levels DNA were determined supernatant induced HepAD38, HBV-expressing HepG2.2.15 cells primary human hepatocytes (PHH), transgenic mice CHB patients. NP-40 proteinase K treatment, sucrose density gradient centrifugation, electron microscopy, northern blot,...
Soil nitrification, an important pathway of nitrogen transformation in ecosystems, produces soil nitrate that influences net primary productivity, while the by-product nitrous oxide, is a significant greenhouse gas. Although there have been many studies addressing microbiology, physiology, and impacting environment factors nitrification at local scales, are very few on rate over large scales. We conducted global synthesis patterns controlling normalized 25°C by compiling 3,140 observations...
Abstract Growing evidence indicates that plant community structure and traits have changed under climate warming, especially in cold or high-elevation regions. However, the impact of these warming-induced changes on ecosystem carbon sequestration remains unclear. Using a warming experiment Qinghai-Tibetan Plateau, we found not only increased species height but also altered composition, collectively resulting taller associated with net productivity (NEP). Along 1,500 km transect promoted NEP...
Sub-acute ruminal acidosis (SARA) is a well-recognized digestive disorder found in particular well-managed dairy herds. SARA can result increased flow of fermentable substrates to the hindgut, which increase production volatile fatty acids, alter structure microbial community, and have negative effect on animal health productivity. However, little known about changes community its relationship with acids during SARA. Four cannulated primiparous (60 90 day milk) Holstein cows were assigned...
The objective of this research was to compare the composition bacterial microbiota associated with ruminal content (RC), epithelium (RE) and faeces Holstein dairy cows. RC, RE faecal samples were collected from six cows when animals slaughtered. Community compositions 16S rRNA genes determined using a MiSeq sequencing platform bacterial-targeting universal primers 338F 806R. UniFrac analysis revealed that communities clearly separated each other. Statistically significant dissimilarities...
Inflammasomes are reported to be abnormally expressed and activated in several malignancies play important roles tumor development. The present study was designed investigate the expression function of NLR family pyrin domain containing protein 3 (NLRP3) inflammasome oral squamous cell carcinoma (OSCC). NLRP3 OSCC lines normal human immortalized epithelial cells (HIOEC) determined by real-time PCR western blot. Immunohistochemistry used examine IL-1β paraffin-embedded tissues. proliferation...
Abstract Nearly 90% of the 390 million ha grasslands in northern China are degraded. ‘Grazing exclusion’ has been implemented as a nature‐based solution to rejuvenate degraded grasslands, but effectiveness rejuvenation processes is uncertain. Here, we investigated effects grazing exclusion on aboveground plant community traits, soil physiochemical and biological properties, mechanisms responsible for enhanced grassland rejuvenation. A meta‐analysis across various studies was used assess...
Abstract Much recent research has explored how global warming and increased nitrogen (N) deposition, two important components of environmental changes, influence the structure functioning natural ecosystems. However, ecosystem dynamics respond to combination long‐term N enrichment remains largely unexplored. We investigated impact addition on temporal stability plant communities in a decade‐long field experiment, conducted desert steppe northern China, using split‐plot design with as...
Abstract Aim Biodiversity drives the delivery of multiple ecosystem functions related to carbon and nutrient cycling (ecosystem multifunctionality, EMF), biodiversity functioning are strongly threatened by intensive grazing in grasslands. However, it remains unclear how regulates EMF changes response grazing. Location Global. Time period From 1992 2018. Major taxa studied Grassland. Methods Here, we conducted a global synthesis using 373 paired observations from 90 published studies address...
Abstract The relationship between biodiversity and ecosystem functioning has mainly focused on plant communities, with comparably little known about soil microbial‐driven functions. Climate change severely threatens microbial roles, but how communities determine multifunctionality under climate is poorly understood. Here, we evaluated the effects of diverse bacterial fungal properties, including gene abundance, diversity network complexity, (nine functions) across a 3000 km transect along...
Fifteen lactating Holstein dairy cows were assigned to three diets in a 3 × Latin square design evaluate the effects of dietary forage sources on rumen microbiota, fermentation and biogenic amines. Diets isonitrogenous isocaloric, with forage/concentrate ratio 45:55 (dry matter basis) but different main sources, namely cornstalk (CS), Leymus chinensis (LC) or alfalfa hay (AH).Pyrosequencing V3-V6 hypervariable coding region 16S rRNA revealed that microbiota was significantly affected by...
Four cannulated primiparous Holstein dairy cows (84 ± 25 DIM) were used in a 2 × crossover experimental design. The two diets contained 40% (low-concentrate diet, or control LC) and 70% (high-concentrate SARA induction HC) concentrate feeds respectively. Milk samples collected on days 17, 18 19 of each period. DNA was extracted from milk sample, pyrosequencing applied to analyse the microbial community.Regardless bacterial community dominated by Actinobacteria, Firmicutes, Proteobacteria...
The objective of this study was to characterize the mRNA expression profile related rumen epithelial inflammation through in vivo and vitro experiments. In experiment, papillae were collected from four dairy cows adapted either a 40 % (LC) or 70 (HC) concentrate feeds for microarray analysis.Results showed that 245 differentially expressed genes (DEGs) detected fed HC relative LC diet. DEGs first annotated, results revealed inflammation-related genes, including IL-1β, IL-2, IL-22, CCL19,...
The responses of soil nitrogen (N) transformations to climate change are crucial for biome productivity prediction under global change. However, little is known about the gross N transformation rates drought gradient. Along an aridity gradient across 2700 km transect drylands on Qinghai-Tibetan Plateau, this study measured three main in both topsoil (0-10 cm) and subsoil (20-30 using laboratorial 15 labeling. relevant abiotic biotic variables were also determined. results showed that...
Integration of human papillomavirus (HPV) viral DNA into the genome has been postulated as an important etiological event during cervical carcinogenesis. Several recent reports suggested a possible role for such integration‐targeted cellular genes (ITGs) in Therefore, comprehensive analysis HPV integration events was undertaken using data collected from 14 publications, with 499 loci on chromosomes included. It revealed that preferred to integrate intragenic regions and gene‐dense...
Subacute ruminal acidosis (SARA) represents one of the most important digestive disorders in intensive dairy farms, and cows are individually different severity SARA risk. The objectives current study were to investigate differences bacterial community metabolome cattle with susceptibility SARA. In present study, 12 initially enrolled experiment. Based on average pH, 4 lowest pH assigned susceptible group (SUS, = 5.76, n 4) highest tolerant (TOL, 6.10, 4). Rumen contents from collected...
Abstract Nitrogen (N), phosphorus (P) and acid deposition are co‐occurring in many ecosystems, likely with complex interactive effects on litter decomposition. Few studies have been conducted to distinguish the of these three factors forest Thus, we performed a 5‐year decomposition experiment N, P, addition temperate Changbai Mountain China, including four types from Pinus koraiensis , Quercus mongolica Tilia amurensis their mixtures. Our results showed that consistently reduced rate,...
Plant and microbial diversity are key to determine ecosystem functioning. Despite the well-known role of local-scale α in affecting vegetation biomass, effects community heterogeneity (β diversity) plants soil microbes on above- belowground biomass (AGB BGB) across contrasting environments still remain unclear. Here, we conducted a dryness-gradient transect survey over 3000 km grasslands Tibetan Plateau. We found that plant β was more dominant than maintaining higher levels AGB, while fungal...