Dan Shang

ORCID: 0000-0003-4308-2758
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About
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Research Areas
  • Vascular anomalies and interventions
  • Abdominal vascular conditions and treatments
  • Esophageal and GI Pathology
  • Venous Thromboembolism Diagnosis and Management
  • Radiomics and Machine Learning in Medical Imaging
  • Nanoplatforms for cancer theranostics
  • Cancer, Hypoxia, and Metabolism
  • RNA Interference and Gene Delivery
  • Diagnosis and Treatment of Venous Diseases
  • Vascular Procedures and Complications
  • Protein Degradation and Inhibitors
  • Lung Cancer Diagnosis and Treatment
  • Photodynamic Therapy Research Studies
  • 14-3-3 protein interactions
  • Angiogenesis and VEGF in Cancer
  • Nanoparticle-Based Drug Delivery
  • MRI in cancer diagnosis
  • Medical Imaging and Pathology Studies
  • Oral Health Pathology and Treatment
  • Extracellular vesicles in disease
  • Vascular Tumors and Angiosarcomas
  • Magneto-Optical Properties and Applications
  • Photonic and Optical Devices
  • Adsorption and biosorption for pollutant removal
  • Higher Education and Teaching Methods

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2024

University of Electronic Science and Technology of China
2007-2024

Union Hospital
2008-2024

Huazhong University of Science and Technology
2007-2024

Union Hospital
2021

Jilin University
2019

Anyang Institute of Technology
2019

Beihang University
2019

North China Institute of Science and Technology
2013

Shandong Tumor Hospital
2010-2013

Background Type G immunoglobulins against ADAMTS13 are the primary cause of acquired (idiopathic) thrombotic thrombocytopenic purpura. However, domains which type anti-ADAMT13 target have not been investigated in a large cohort patients with purpura.Design and Methods Sixty-seven idiopathic purpura were prospectively collected from three major U.S. centers. An enzyme-linked immunosorbent assay determined plasma concentrations anti-ADAMTS13 immunoglobulins, whereas immunoprecipitation plus...

10.3324/haematol.2009.019299 article EN cc-by-nc Haematologica 2010-04-07

An AIE-active photosensitizer, <bold>TTVPHE</bold>, can fast penetrate into cancer cells and efficiently trigger mitochondria-dependent apoptotic pathway with self-monitoring ability.

10.1039/d0qm00503g article EN cc-by-nc Materials Chemistry Frontiers 2020-01-01

Through facilitating DNA homologous recombination repair, PPIP5K2 has been proven to be essential for improving colorectal cancer survival in our previous research. However, its function the tumorigenesis of NSCLC, most common and primary cause cancer-related death globally, is still unknown. Here, we initially discovered that had significant effects on proliferation NSCLC cells through loss- gain-of-function assays vitro vivo. Moreover, capable regulating metastasis an EMT-dependent manner....

10.3390/cancers16030590 article EN Cancers 2024-01-30

As a gene therapy strategy, RNA interference (RNAi) offers tremendous tumor potential. However, its therapeutic efficacy is restricted by inferior ability for targeted delivery and cellular uptake of small interfering (siRNA). This study sought to develop dual-ligand nanoparticle (NP) system loaded with siRNA promote efficacy. We synthesized dual receptor-targeted chitosan nanosystem (GCGA), whose target function was controlled the ligands galactose lactobionic acid (LA) glycyrrhetinic (GA)....

10.3389/fbioe.2020.00512 article EN cc-by Frontiers in Bioengineering and Biotechnology 2020-06-10

Objectives The objective of this study was to evaluate the efficacy and safety in patients with acute lower extremity deep venous thrombosis who underwent pharmacomechanical thrombectomy (PMT, AngioJet mechanical thrombus aspiration). Methods In retrospective, 424 consecutive from three institutions were enrolled January 2015 December 2018. Of these, divided into two groups, group ( n = 186) catheter-directed thrombolysis (CDT) 238). Evaluation indexes including limb circumference...

10.1177/1708538120958595 article EN Vascular 2020-09-22

One of the primary causes lumen narrowing is vascular injury induced during medical procedures. Vascular disrupts integrity endothelium, triggering platelet deposition, leukocyte recruitment, and release inflammatory factors. This, in turn, induces proliferation smooth muscle cells (VSMCs), leading to neointima formation. However, molecular mechanism underlying VSMC following remains unknown. KIF11 critical regulating cell cycle by forming bipolar spindles mitotic metaphase. This process may...

10.3389/fphar.2024.1392352 article EN cc-by Frontiers in Pharmacology 2024-08-06

Firstly, this paper analyzes the significance and demand on Intelligent power. Then a solution of home intelligent power system based ZigBee is proposed. Hardware components proposed in work mainly consist AT91SAM9G20 as core gateway controller, CC430F6137 network node power, well construction system. Software comprise migration controller operating system, writing application program user interface program. Design software object-oriented design pattern modular concept, which Home divided...

10.1109/cecnet.2013.6703428 article EN 2013-11-01

Objectives The clinical outcomes, safety, and efficacy of endovascular management are explored for symptomatic isolated superior mesenteric artery dissection (ISMAD). Methods In this retrospective study, 51 consecutive patients with ISMAD received from three institutions between January 2011 December 2019.These were categorized into group A (endovascular treatment was used as the first-line therapy) B(endovascular second-line therapy). general epidemiological data, manifestations,...

10.1177/1708538120950110 article EN Vascular 2020-08-20

Objectives The aim of this study was to evaluate the clinical features and management strategy for patients with symptomatic spontaneous isolated celiac artery dissection (SICAD). Methods In retrospective study, consecutive SICAD from two institutions were included. demographics, manifestations, comorbidities, imaging findings treatment selection obtained medical records. general epidemiological data, regimens follow-up outcomes analysed. Results Patients divided into conservative group...

10.1177/1708538120986295 article EN Vascular 2021-01-12

Recurrent aphthous stomatitis (RAS) is one of the most common chronic oral diseases with morbidity ranging from 5% to 20%. The pathogenesis still not fully understood though immune dysregulation and local trauma have been implicated curative effect that can be achieved through current therapy mainly alleviate pain. So, understanding its molecular mechanisms allow prevention treatment RAS at level.14 normal tissues 14 ulcerated were subjected Affymetrix Human Genome U133 Plus 2.0 Array...

10.7754/clin.lab.2016.160721 article EN Clinical Laboratory 2017-01-01

Objectives The aim of this study was to evaluate the computed tomography follow-up outcomes and radiographic findings symptomatic isolated mesenteric artery dissection (IMAD) after conservative management. Methods In retrospective study, 130 consecutive patients with IMAD from three institutions were enrolled January 2011 December 2019. general epidemiological data, clinical manifestations, first-episode symptoms, imaging findings, treatment strategy selection analyzed medical records....

10.1177/1708538120918415 article EN Vascular 2020-07-01

The multifrequency diffraction effects of guided optical waves with multiple magnetostatic forward volume (MSFVWs) excited in magnetooptic (MO) film waveguides under a normal bias magnetic field are theoretically studied for the first time. Multifrequency MO coupled-mode equations and analytic solution small-signal approximation presented. It is shown that, case, second or higher order can be neglected coupling principal efficiency (PDE) proportional to MSFVW power. Thus, method determining...

10.1143/jjap.46.6710 article EN Japanese Journal of Applied Physics 2007-10-01

Abstract Objective: Spontaneous isolated celiac artery dissection (SICAD) is a rare condition, and its natural history outcomes have not been thoroughly studied. The aim of this study was to review our institution’s experience in the evaluation, treatment, patients with SICAD. Methods: A retrospective conducted on 76 who presented SICAD between January 2010 July 2022. clinical manifestations, initial radiological findings, methods treatment follow-up computed tomography were reviewed,...

10.21203/rs.3.rs-3801303/v1 preprint EN cc-by Research Square (Research Square) 2024-01-03

Objectives Diagnosis and treatment of isolated mesenteric artery dissections (IMAD) are overlooked. The purpose this study was to assess the clinical feature, possible diagnostic errors methods. Methods From January 2010 December 2017, 99 consecutive patients who were diagnosed with IMAD on computed tomography angiography enrolled retrospectively. Thirty-nine misdiagnosed patients, false negative, 60 accurate diagnosis revealed compared. In addition, therapeutic schemes evaluated. Results...

10.1177/1708538119882280 article EN Vascular 2019-10-10
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