Ji-Xiao Zhu

ORCID: 0000-0003-4342-3444
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Research Areas
  • Cancer-related cognitive impairment studies
  • Curcumin's Biomedical Applications
  • Cholinesterase and Neurodegenerative Diseases
  • Inflammasome and immune disorders
  • Pharmacological Effects of Natural Compounds
  • Natural product bioactivities and synthesis
  • Medicinal Plants and Bioactive Compounds
  • Phytochemistry and Biological Activities
  • Liver Disease Diagnosis and Treatment
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Bioactive Compounds and Antitumor Agents
  • Nephrotoxicity and Medicinal Plants
  • Medical Research and Treatments
  • Tryptophan and brain disorders
  • Metabolomics and Mass Spectrometry Studies
  • Diet, Metabolism, and Disease
  • Music Therapy and Health
  • Alcohol Consumption and Health Effects
  • Gout, Hyperuricemia, Uric Acid
  • Neuroscience and Music Perception
  • Flavonoids in Medical Research
  • Pharmacological Effects of Medicinal Plants
  • Ginseng Biological Effects and Applications
  • Stress Responses and Cortisol
  • Immune Response and Inflammation

Jiangxi University of Traditional Chinese Medicine
2018-2024

Huaqiao University
2021

The goal of this research was to develop a fast, reliable, and sensitive method simultaneously quantify five key components Huai-hua Powder (HHP) in rat plasma with genistein served as the internal standard. Furthermore, established used perform comparative evaluation pharmacokinetic properties HHP normal rats ulcerative colitis (UC).

10.1093/jpp/rgae062 article EN other-oa Journal of Pharmacy and Pharmacology 2024-06-24

The aim is to establish a model of nonalcoholic fatty liver disease (NAFLD) caused by feeding with high-fat, high-fructose, and high-cholesterol diet (HFFCD) in golden hamsters, investigate the characteristics NAFLD metabolite changes tissue. Golden hamsters were fed HFFCD or control diets for six weeks. Body weight, abdominal fat index, index was assessed, serum parameters, hepatic histology, metabolites examined. results showed that body fat, significantly increased group, level total...

10.1515/znc-2021-0201 article EN Zeitschrift für Naturforschung C 2022-03-14

Abstract Lagotis brachystachya Maxim is an herb widely used in traditional Tibet medicine. Our previous study indicated that total extracts from could lower uric acid levels. This aimed to further elucidate the active components (luteolin, luteoloside and apigenin) isolated underlying mechanism vitro vivo. The results showed treatment with luteolin reversed reduction of organic anion transporter 1 (OAT1) levels, while apigenin attenuated elevation urate (URAT1) glucose 9 (GLUT9) levels...

10.21203/rs.3.rs-283474/v1 preprint EN cc-by Research Square (Research Square) 2021-03-12

Background: Cisplatin, a commonly used chemotherapy drug can significantly increase the survival rate of cancer patients worldwide. However, it often causes various side effects including cognitive impairment. Curcumin has been demonstrated to be effective in treatment neurobiological diseases. Methods: In present study, mechanism curcumin on improvement was evaluated male C57BL mice treated with cisplatin. Behavioral evaluation open field test, novel object recognition test and morris water...

10.2139/ssrn.3292581 article EN SSRN Electronic Journal 2018-01-01

Ethnopharmacological relevance: L. integra W. WSmith is an important origin plant of the famous Tibetan medicine HERBA LAGOTIS. It was clinically documented in as a drug used to treat 'Chi Ba Disease', whose symptoms are similar ulcerative colitis (UC).Aims this study: We investigated effective materials and holistic mechanisms Smith against UC.Materials methods: The ingredients were comprehensively analyzed using UHPLC-Q-TOF/MS method. network pharmacology method, which included target...

10.2139/ssrn.4174956 article EN SSRN Electronic Journal 2022-01-01
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