Huilian Huang

ORCID: 0000-0003-1988-0354
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About
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Research Areas
  • Natural product bioactivities and synthesis
  • Phytochemistry and Biological Activities
  • Phytochemical Studies and Bioactivities
  • Phytochemistry and Bioactive Compounds
  • Chromatography in Natural Products
  • Traditional Chinese Medicine Analysis
  • Phytochemical compounds biological activities
  • Ginseng Biological Effects and Applications
  • Angiogenesis and VEGF in Cancer
  • Pharmacological Effects of Natural Compounds
  • Bioactive natural compounds
  • Cancer, Lipids, and Metabolism
  • Lipid metabolism and disorders
  • Medicinal Plant Pharmacodynamics Research
  • Botanical Studies and Applications
  • Bioactive Natural Diterpenoids Research
  • Traditional and Medicinal Uses of Annonaceae
  • Essential Oils and Antimicrobial Activity
  • Plant biochemistry and biosynthesis
  • Fungal Biology and Applications
  • Bioactive Compounds and Antitumor Agents
  • Medicinal plant effects and applications
  • Flavonoids in Medical Research
  • Metabolomics and Mass Spectrometry Studies
  • Phytochemicals and Antioxidant Activities

Jiangxi University of Traditional Chinese Medicine
2016-2025

Hubei University of Technology
2025

Beijing Tongren Hospital
2023-2024

Capital Medical University
2023-2024

Southwest Forestry University
2024

Huazhong Agricultural University
2019-2023

Zhejiang University
2023

Huzhou Central Hospital
2023

Huzhou University
2023

Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine
2020-2021

Preharvest calcium application has been shown to increase broccoli microgreen yield and extend shelf life. In this study, we investigated the effect of on its metabolome using ultra-high-performance liquid chromatography with mass spectrometry. The data collected were analyzed principal component analysis orthogonal projection latent structural discriminate analysis. Chemical composition comparison shows that glucosinolates, a very important group phytochemicals, are major compounds enhanced...

10.1021/jf504710r article EN Journal of Agricultural and Food Chemistry 2015-01-16

Carboxylesterase 2 (CES 2) is a key enzyme in the activation of prodrug irinotecan (CPT-11) treatment against colorectal cancer and also has some relationship with side effect CPT-11 clinical applications.

10.1039/d0tb02673e article EN Journal of Materials Chemistry B 2021-01-01

Abstract In this research, a novel rice composed of grated flour, whey protein, and lotus seedpod oligomeric procyanidins was developed through pre‐gelatinization combined with twin‐screw extrusion techniques. The nutritional, physicochemical properties biological activities the composite were systematically studied. Results revealed that exhibited 17.6% reduction in cooking time, 23.6% increase gelatinization degree, 51.8% decrease rehydration water absorption compared to conventional rice....

10.1002/fob2.70001 article EN cc-by Food biomacromolecules. 2025-03-17

Four new jatrophane-type diterpenoids (1−4), together with 16 known related compounds, were isolated from the Chinese medicinal plant Euphorbia helioscopia. The structures of 1−4 determined on basis spectroscopic and chemical methods. Cytotoxicity compounds against HeLa MDA-MB-231 cells was evaluated, only helioscopinolide A (5) euphornin (3a) being active.

10.1021/np0706163 article EN Journal of Natural Products 2008-03-06

Abstract Ginsenoside Rb 1 is an active protopanaxadiol saponin from Panax species. In order to compare the similarities and differences of microbial mammalian metabolisms ginsenoside , transformation by Acremonium strictum metabolism in rats were comparatively studied. Microbial AS 3.2058 resulted formation eight metabolites. Ten metabolites (M1–M10) detected vivo study them identified as same compounds those obtained liquid chromatography–tandem mass spectrometry analysis comparison with...

10.1002/bmc.1001 article EN Biomedical Chromatography 2008-04-02

Flow injection mass spectrometry and proton nuclear magnetic resonance spectrometry, two metabolic fingerprinting methods, DNA sequencing were used to identify authenticate <i>Actaea</i> species. Initially, samples of <i>Actaea racemosa</i> from a single source distinguished other species based on principal component analysis soft independent modeling class analogies flow fingerprints. The chemometric results for agreed well showed similar agreement throughout the study. using sequence data...

10.1055/s-0035-1558113 article EN Planta Medica 2015-12-21

With the aging of many populations, cognitive and motor dysfunction caused by ischemic stroke (IS) secondary to long-term chronic cerebral ischemia presents a global problem. Enriched environment (EE), classic paradigm response genetic interaction, has shown tremendous influence on brain. This research aimed investigate potential effect EE function in mice with IS. In hypoperfusion (CCH) phase, treatment improved behavior performance alleviating neuronal loss white matter myelin damage,...

10.3389/fimmu.2023.1114596 article EN cc-by Frontiers in Immunology 2023-03-09

Three 20(S)-protopanaxatriol-type saponins, ginsenoside-Rg1 (1), notoginsenoside-R1 (2), and ginsenoside-Re (3), were transformed by the fungus Absidia coerulea (AS 3.3389). Compound 1 was converted into five metabolites, ginsenoside-Rh4 (4), 3β,2β,25-trihydroxydammar-(E)-20(22)-ene-6-O-β-d-glucopyranoside (5), 20(S)-ginsenoside-Rh1 (6), 20(R)-ginsenoside-Rh1 (7), a mixture of 25-hydroxy-20(S)-ginsenoside-Rh1 its C-20(R) epimer (8). 2 10 20(S)-notoginsenoside-R2 (9), 20(R)-notoginsenoside-R2...

10.1021/np070053v article EN Journal of Natural Products 2007-07-01
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