Taojing Li
A5028140311- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 Impact on Reproduction
- Advanced Drug Delivery Systems
Abstract To investigate the duration of humoral immune response in convalescent coronavirus disease 2019 (COVID-19) patients, we conduct a 12-month longitudinal study through collecting total 1,782 plasma samples from 869 donors Wuhan, China and test specific antibody responses. The results show that positive rate IgG against receptor-binding domain spike protein (RBD-IgG) to severe acute respiratory syndrome 2 (SARS-CoV-2) COVID-19 exceeded 70% for 12 months post diagnosis. level RBD-IgG...
Abstract To investigate the duration of humoral immune response in convalescent coronavirus disease 2019 (COVID-19) patients, we conduct a 12-month longitudinal study through collecting total 1,782 plasma samples from 869 donors Wuhan, China and test specific antibody responses. The results show that positive rate IgG against receptor-binding domain spike protein (RBD-IgG) to severe acute respiratory syndrome 2 (SARS-CoV-2) COVID-19 exceeded 70% for 12 months post diagnosis. level RBD-IgG...
Coronavirus disease 2019 (COVID-19) remains a global public health threat. Hence, more effective and specific antivirals are urgently needed. Here, COVID-19 hyperimmune globulin (COVID-HIG), passive immunotherapy, is prepared from the plasma of healthy donors vaccinated with BBIBP-CorV (Sinopharm vaccine). COVID-HIG shows high-affinity binding to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor-binding domain (RBD), N-terminal S nucleocapsid protein;...
The immunity of patients who recover from coronavirus disease 2019 (COVID-19) could be long lasting but persist at a lower level. Thus, recovered still need to vaccinated prevent reinfection by severe acute respiratory syndrome 2 (SARS-CoV-2) or its mutated variants. Here, we report that the inactivated COVID-19 vaccine can stimulate in maintain high levels anti-receptor-binding domain (RBD) and anti-nucleocapsid protein (NP) antibody titers within 9 months, neutralizing activity against...