- Schizophrenia research and treatment
- Mental Health Treatment and Access
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health and Psychiatry
- Mental Health Research Topics
- Bipolar Disorder and Treatment
- Family Caregiving in Mental Illness
- Functional Brain Connectivity Studies
- Obsessive-Compulsive Spectrum Disorders
- Sexuality, Behavior, and Technology
- LGBTQ Health, Identity, and Policy
- Attachment and Relationship Dynamics
- Intimate Partner and Family Violence
- Child Abuse and Trauma
- Tryptophan and brain disorders
- Health Systems, Economic Evaluations, Quality of Life
- Psychology Research and Bibliometrics
- Personality Disorders and Psychopathology
- Psychological Treatments and Disorders
- Stress Responses and Cortisol
- Resilience and Mental Health
- Neuroscience and Music Perception
- Advanced Neuroimaging Techniques and Applications
- Bullying, Victimization, and Aggression
- Diet and metabolism studies
Instituto Nacional de Psiquiatría
2016-2025
Consejo Nacional de Humanidades, Ciencias y Tecnologías
2016-2022
Universidad Nacional Autónoma de México
2014-2021
University of Bologna
2020
Universitat Autònoma de Barcelona
2011-2014
Ministerio de Asuntos Exteriores, Unión Europea y Cooperación
2011
Reliable, clinically useful, and globally applicable diagnostic classification of mental disorders is an essential foundation for global health. The World Health Organization (WHO) nearing completion the 11th revision International Classification Diseases Related Problems (ICD‐11). present study assessed inter‐diagnostician reliability accounting greatest proportion disease burden highest levels service utilization – schizophrenia other primary psychotic disorders, mood anxiety fear‐related...
In this paper we report the clinical utility of diagnostic guidelines for ICD-11 mental, behavioural and neurodevelopmental disorders as assessed by 339 clinicians in 1,806 patients 28 mental health settings 13 countries. Clinician raters applied schizophrenia other primary psychotic disorders, mood (depressive bipolar disorders), anxiety fear-related specifically associated with stress. ratings proposed were very positive overall. The perceived easy to use, corresponding accurately...
Adverse childhood experiences (ACEs) are common in people at clinical high-risk for psychosis (CHR), however, the relationship between ACEs and long-term outcomes is still unclear. This study examined associations CHR individuals. 344 individuals 67 healthy controls (HC) were assessed using Childhood Trauma Questionnaire (CTQ), Bullying Experience of Care Abuse (CECA). followed up to 5 years. Remission from state, transition (both defined with Comprehensive Assessment an At Risk Mental...
BackgroundA key clinical challenge in the management of individuals at high risk for psychosis (CHR) is that it difficult to predict their future outcomes. Here, we investigated if levels circulating molecular lipids are related adverse outcomes this group.MethodsSerum lipidomic analysis was performed 263 CHR and 51 healthy control subjects, who were then clinically monitored up 5 years. Machine learning used identify lipid profiles discriminated between subgroups subjects with distinct...
Abstract Background Bullying has become a significant global health problem due to its high prevalence worldwide and long-term consequences on mental health, including the onset of psychotic symptoms. This study focuses exploring bullying across three groups Mexican individuals with different levels psychosis risk symptoms: non-psychosis (non-PR), psychotic-like experiences (PLEs), at clinically high-risk for (CHR-P). In addition, we compare sociodemographic features, self-esteem,...
Abstract Introduction Diagnoses of anxiety and/or depression are common in subjects at Ultra-High Risk for Psychosis (UHR) and associated with extensive functional impairment. Less is known about the impact affective comorbidities on prospective course attenuated psychotic symptoms (APS). Method Latent class mixed modelling identified APS trajectories 331 UHR assessed baseline, 6, 12, 24 months follow-up. The prognostic value past, one-year DSM-IV depressive or disorders was investigated...
Abstract Aims The understanding of factors related to poor subjective quality life (s Q o L ) in early psychosis patients is important for both research and treatment efforts. This study examined how s associated with age at onset prodromal symptoms, duration untreated illness ( DUI ), symptom severity, premorbid functioning current functional impairment A t‐ R isk M ental S tate ARMS patients. Methods Forty were assessed , functioning, social role functioning. Results expected, a large...
Background/Objective: The World Health Organization's diagnostic guidelines for ICD-11 mental and behavioural disorders must be tested in clinical settings around the world to ensure that they are clinically useful genuinely global. objective is evaluate inter-rater reliability utility of psychotic, mood, anxiety- stress-related Mexican patients. Method: Adult volunteers exhibiting selected symptoms were referred from pre-consultation unit a public psychiatric hospital an interview by pair...
Epidemiological evidence has linked an array of sociodemographic and psychosocial factors with increased risk developing psychosis. However, research in samples from low- middle-income countries is still scarce. This study used a Mexican sample to explore (i) differences between individuals without positive screen for Clinical High-Risk psychosis (CHR), (ii) associated screening CHR. The consisted 822 the general population who completed online survey. Of participants, 17.3% ( n = 142) met...
Mechanisms underlying the manifestation of relatives' expressed emotion (EE) in early stages psychosis are still not properly understood. The present study aimed to examine whether psychological distress and subjective appraisals illness predicted EE dimensions over-and-above patients' poor clinical functional status. Baseline patient-related variables relatives attributes comprising criticism, emotional over-involvement (EOI), distress, attributions were assessed 91 patients their...
The high prevalence of obsessive-compulsive symptoms (OCS) among subjects at Ultra-High Risk (UHR) for psychosis is well documented. However, the network structure spanning relations between OCS and risk mental state as assessed with Comprehensive Assessment At Mental States (CAARMS) has not yet been investigated. This article aimed to use a approach investigate associations CAARMS in large sample individuals different levels psychosis.Three hundred forty-one UHR 66 healthy participants were...
Intimate partner violence (IPV) is a global public health problem that has been shown to lead serious mental consequences. Due its frequent co-occurrence with psychiatric disorders, it important assess for IPV in settings improve treatment planning and referral. However, lack of training how identify respond identified as barrier the assessment IPV. The present study seeks better understand this IPV-related gap by assessing professionals' experiences factors contribute their likelihood...
Background: Transgender people are often victims of multiple types violence across several areas life due to society's marked intolerance gender nonconformity. Objective: This study seeks describe experiences in transgender individuals and explore the relationship between different specific, high-risk incongruence social rejection factors during adolescence. Method: The sample consisted 245 adults receiving transgender-related health services at a public specialised clinic Mexico City....
This study examined the effects of a three-month Family-to-Family (FTF) Education Program on expressed emotion and subjective knowledge about mental illness among relatives Mexican patients with severe disorders.A total 230 disorders completed self-reported questionnaires before (pretest) after (posttest) FTF program.FTF led to reductions in negative emotional attitudes improved understanding disorder, regardless sex or age relative.This supported evidence-based practice population confirmed...
Abstract Aim Cognitive disturbances typically precede the onset of overt psychotic symptoms and represent a neurobiological marker for psychosis risk that is also associated with poor functional outcomes. The Measure Insight into Cognition‐Self Report (MIC‐SR) widely used 12‐item questionnaire assesses perceived frequency cognitive impairment in domains executing functioning, attention, memory. However, MIC‐SR not available Spanish, one most spoken languages worldwide. present study aimed to...