A5100715298- Bladder and Urothelial Cancer Treatments
- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Renal cell carcinoma treatment
- Urinary and Genital Oncology Studies
- Ureteral procedures and complications
- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Renal and related cancers
- Renal and Vascular Pathologies
- Kidney Stones and Urolithiasis Treatments
- Ferroptosis and cancer prognosis
- Urologic and reproductive health conditions
- Diverticular Disease and Complications
- Cancer, Hypoxia, and Metabolism
- Cryospheric studies and observations
- Adrenal and Paraganglionic Tumors
- Climate change and permafrost
- Prostate Cancer Treatment and Research
- Colorectal Cancer Surgical Treatments
- MRI in cancer diagnosis
- Cancer-related Molecular Pathways
- Urinary Tract Infections Management
- Cancer Immunotherapy and Biomarkers
Northwest Normal University
2025
Hangzhou Medical College
2017-2024
Zhejiang Provincial People's Hospital
2015-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2022-2023
Chongqing Medical University
2022-2023
Zhejiang Chinese Medical University
2023
Qingdao University
2022-2023
Soochow University
2023
Bengbu Medical College
2023
Beijing Forestry University
2022
Abstract Tislelizumab, an anti‐programmed death protein‐1 (PD‐1) monoclonal antibody, was engineered to minimize binding the FcγR on macrophages abrogate antibody‐dependent phagocytosis, a mechanism of T‐cell clearance and potential resistance anti‐PD‐1 therapy. This single‐arm phase 2 trial (NCT04004221/CTR20170071) assessed safety, tolerability, efficacy tislelizumab in patients with PD‐L1‐positive urothelial carcinoma who progressed during/following platinum‐containing therapy had no...
Abstract High vapor pressure deficit (VPD) and low soil moisture (SM) lead to atmospheric droughts, which can stress carbon‐water coupling in terrestrial ecosystems. However, the strong collinearity between VPD SM, particularly under certain climatic conditions, makes it challenging disentangle their independent contributions carbon water dynamics land‐atmosphere interactions. This study aimed clarify long‐term response of global vegetation coupling, based on ecosystem water‐use efficiency...
As the direct subject of collective forestland tenure reform, increasing farmers’ income is an important goal reform and key to sustainable management forest resources. Based on survey data 1276 rural households in 18 counties 9 provinces, we construct a theoretical analysis framework impact household from perspective differentiation elucidate mechanism effect context differentiation. The results empirical show that, firstly, significantly increases total income, forestry off-farm...
Renal cancer is one of the most deadly urological malignancies. Currently, there still a lack effective treatment. Our purpose was to explore mechanisms miR-122-5p in renal cancer.The expression levels and pyruvate kinase M2 (PKM2) cells were detected by RT-qPCR Western blot analyses, respectively. Then, we measured cell viability after knockdown PKM2 using CCK-8 assay. Moreover, flow cytometry used investigate cycle apoptosis cells. The migration transfected inhibitor siPKM2 then wound...
The relationship between dairy consumption and gastric cancer risk has not been well studied. We therefore performed a update meta-analysis to evaluate the relationship. Published cohort case-control studies were identified via computer searches reviewing reference lists of key articles. Random effects was used pool from 5 29 studies. odds ratio for overall association 1.20 (95%confidence interval: 1.04-1.39). combined estimate similar population-based (odds = 1.27, 95%confidence 1.00-1.61),...
Purpose: To report our experience in the laparoscopic extravascular management of nutcracker syndrome. Patients and Methods: Three patients (two men one woman) between ages 20 35 years (mean 25.7 y) underwent stent placement left renal vein for syndrome that is associated with severe recurrent gross hematuria gonadal varices. The postoperative follow-up was 16 to 37 months 25.3 mos). Results: All met criteria establishing diagnosis Ultrasonography, CT, MRI revealed visible entrapment...
The purpose of this study was to investigate the predictors metastatic patterns upper tract urothelial carcinoma (UTUC) and analyze surgical outcomes different UTUC. Data on patients with UTUC from 2010 2017 were retrieved Surveillance, Epidemiology, End Results Program (SEER) database. Kaplan–Meier analysis applied compare patients' survival distributions. Univariate multivariate logistic regression used assess specific site-specific metastases, while competitive risk estimate...
Primary synovial sarcoma of the prostate is an uncommon malignant tumor. There are few cases reported in English medical literature to date. Here, we present a case 22-year-old man with primary metastatic liver and lung. To our knowledge, only six reports involving have been previously published. We also reviewed previous treatments prognoses evaluate proper treatment for this disease.
Abstract Background Radical nephrectomy (RN) is the standard treatment for localized renal cell carcinoma. The decrease in nephrons from RN could lead to postoperative chronic kidney disease (CKD). In this study, we aim investigate incidence and risk factors CKD patients who have received RN. Methods A Total of 1233 underwent radical Zhejiang Provincial People’s Hospital January 2010 December 2018. Those had an abnormal function before surgery or were lost follow-up excluded. Five hundred...
Bladder cancer (BCa) is among the most prevalent cancers worldwide. However, effectiveness of intravesical therapy for BCa limited due to short dwell time and presence permeation barrier.Nanocomplexes were self-assembled between DNA hendeca-arginine peptide (R11). Stepwise instillation R11 generated nanocomplexes significantly enhanced targeting capacity penetration efficiency in therapy. The involved mechanism cellular uptake was determined. therapeutic effect verified preclinically murine...
Abstract Background There is now ample evidence suggesting that extracorporeal shock wave therapy (ESWT) can improve hip mobility and reduce pain in patients with osteonecrosis of the femoral head (ONFH). The ability ESWT to cure bone marrow edema syndrome (BMES) ONFH, 12 weeks after initial course ESWT, needs be verified further more relevant clinical research-based should consolidated. This study aimed evaluate efficacy for BMES caused by ONFH. Methods retrospective cohort included 67 ONFH...
To compare the long-term clinical and oncologic outcomes of laparoscopic partial nephrectomy (LPN) radical (LRN) in patients with renal cell carcinoma (RCC) > 4 cm.We retrospectively reviewed records all who underwent LPN or LRN our department from January 2012 to December 2017. Of 151 met study selection criteria, 54 received LPN, 97 LRN. After propensity-score matching, 51 matched pairs were further analyzed. Data on patients' surgical data, complications, histologic function, survival...
Purpose: This study evaluated the efficacy and safety of enzalutamide vs placebo, both combined with androgen deprivation therapy, in Chinese men metastatic hormone-sensitive prostate cancer. Materials Methods: Patients were randomized 2:1 to 160 mg/day or combination therapy. The primary trial end point was time prostate-specific antigen progression. Selected secondary points included radiographic progression-free survival, castration resistance, initiation new antineoplastic undetectable...