A5003243605- Global Maternal and Child Health
- Malaria Research and Control
- Child Nutrition and Water Access
- Pregnancy and preeclampsia studies
- Mosquito-borne diseases and control
- Reproductive System and Pregnancy
- Complement system in diseases
- Reproductive Health and Contraception
- Adolescent Sexual and Reproductive Health
- Reproductive tract infections research
- Global Health and Epidemiology
- Poverty, Education, and Child Welfare
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Antibiotic Resistance in Bacteria
- Prenatal Screening and Diagnostics
- Apelin-related biomedical research
- Iron Metabolism and Disorders
- Pregnancy and Medication Impact
- Food Security and Health in Diverse Populations
- Syphilis Diagnosis and Treatment
- Antibiotic Use and Resistance
- Liver Disease and Transplantation
- Neonatal and Maternal Infections
- Healthcare Systems and Practices
Institut de Recherche en Sciences de la Santé
2017-2024
Centre Muraz
2018-2023
UCLouvain
2020-2023
Cliniques Universitaires Saint-Luc
2020
Infants are thought to be protected against malaria during the first months of life mainly due passage maternal antibodies. However, in high transmission settings, early infancy is not uncommon and susceptibility infections varies between individuals. This study aimed determine morbidity infection childhood rural Burkina Faso. Malariometric indices were determined over 1-year follow-up a birth cohort 734 infants living Nanoro health district. Clinical episodes by passive case detection at...
Low birth weight (LBW) is a major factor of neonate mortality that particularly affects developing countries. However, the scarcity data to support decision making reduce LBW occurrence obstacle in sub-Saharan Africa. The aim this research was determine prevalence and associated factors at Yako health district rural area Burkina Faso.A cross sectional survey conducted four peripheral centers among mothers their newly delivered babies. mothers' socio-demographic obstetrical characteristics...
Abstract Background Exposure during pregnancy to malaria and sexually-transmitted infections is associated with adverse birth outcomes including low weight (LBW). This study aimed at assessing if the adjunction of two doses azithromycin sulfadoxine-pyrimethamine for intermittent preventive treatment in can reduce LBW. Methods A parallel-groups, open-label randomized controlled trial involving pregnant women (16 35 years age 12 24 weeks gestation as confirmed by last menstrual period or...
Malnutrition in children is a serious health problem, especially Sub-Saharan Africa, with heavy socioeconomic burdens. The prevalence of stunting remains high Burkina Faso. There need to further investigate undernutrition and identify the major factors contributing its persistence. We aimed assess nutritional status aged under five years associated conducted second study using baseline household survey impact assessment performance-based financing program. analysis focused on data 10,032...
Introduction: anemia, the commonest nutritional deficiency disorder among pregnant women in sub-Saharan Africa, is associated with severe peripartum complications. Its regular monitoring necessary to timely inform clinical and preventive decision-making. The aim of this study was assess prevalence determinants anemia rural areas Burkina Faso.
Background Malaria and curable sexually transmitted infections (STI) are the most common known to have a severe impact on pregnancy outcomes in sub-Saharan Africa. This study aims assess marginal joint prevalence of symptomatic cases malaria STI pregnant women living rural settings Burkina Faso their associated factors, after more than decade introduction intermittent preventive treatment (IPT-SP). Methods We carried out an observational two health districts Burkina, namely Nanoro Yako....
Abstract Background Malaria in pregnancy can result placental infection with fetal implications. This study aimed at assessing malaria (PM) prevalence and its associated factors a cohort of pregnant women peripheral their offspring. Method The data were collected the framework clinical trial on treatments for . Placental was diagnosed by histopathological detection parasites and/or pigment placenta biopsies taken delivery. Factors PM assessed using logistic regression. Results Out 745...
Background: Adolescence is associated with adverse fetal outcome, particularly in resources limited settings. We assessed the association between mother’s age and low birth weight or prematurity Nanoro, a rural health district of Burkina Faso. Methods: collected data on mothers their newborns framework “Safe Efficacious Artemisinin-based Combination Treatments for African Pregnant Women Malaria” clinical trial. Low was defined as outcome. Logistic regression used to compare its occurrence...
Although consensus exists that malaria in pregnancy (MiP) increases the risk of infancy, and eventually nonmalarial fevers (NMFs), there is a lack conclusive evidence benefits MiP preventive strategies infants.In Burkina Faso, birth cohort study was nested to clinical trial assessing effectiveness community-based scheduled screening treatment combination with intermittent sulfadoxine-pyrimethamine (CSST/IPTp-SP) prevent placental malaria. Clinical episodes asymptomatic infections were...
Abstract Background Ultrasound scanning during the 2nd or 3rd trimester of pregnancy for fetal size disturbances screening is heavily dependent choice reference chart. This study aimed to assess agreement Salomon and Intergrowth 21st equations in evaluating biometric measurements a rural area Burkina Faso, measure effect changing Methods Data collected Nazoanga, between October 2010 2012, clinical trial safety efficacy several antimalarial treatments pregnant women were analyzed. We included...
Diagnosis of malaria in pregnancy is problematic due to the low sensitivity conventional diagnostic tests (rapid test and microscopy), which exacerbated peripheral parasite densities, lack clinical symptoms. In this study, six potential biomarkers support diagnosis were evaluated.Blood samples collected from pregnant women at antenatal clinic visits delivery. Microscopy real-time PCR performed for biomarker analyses by ELISA (interleukin 10, IL-10; tumor necrosis factor-α, TNF-α; soluble...
The WHO recommends continuous surveillance of malaria in endemic countries to identify areas and populations most need for targeted interventions. aim this study was assess the prevalence its associated factors among first antenatal care (ANC) attendees rural Burkina Faso.A cross-sectional survey conducted between August 2019 September 2020 at Yako health district included 1067 ANC attendees. Sociodemographic, gyneco-obstetric, medical characteristics were collected. Malaria diagnosed by...
Malaria and curable sexually transmitted infections (STIs) are severe associated with poor pregnancy outcomes in sub-Saharan countries. These responsible for low birth weight, preterm birth, miscarriage. In Burkina Faso, many interventions recommended by the World Health Organization were implemented to control impact of these infections. After decades intervention, we assessed on rural setting Faso.Antenatal care delivery data pregnant women attending health facilities 2016 2017 collected...
Background The hormonal shift occurring in pregnant women is crucial for the outcome of pregnancy. We conducted a study living malaria endemic area to determine potential effect gestational age on modulation endocrine system by cortisol and prolactin production during Methods Primigravidae multigravidae with between 16–20 weeks were included followed up delivery 6–7 thereafter. Venous blood was collected at scheduled visit: Visit 1 (V1; amenorrhea), 2 (V2; 28 ±1 pregnancy), 3 (V3; 32 Visit4...
Abstract Background Malaria and sexually transmitted/reproductive tract infections (STI/RTI) are leading preventable causes of low birthweight in sub-Saharan Africa. Reducing their impact on pregnancy outcomes requires efficient interventions that can be easily integrated into the antenatal care package. The paucity data malaria STI/RTI coinfection, however, limits efforts to control these infections. This study aimed determine prevalence associated factors coinfection among pregnant women...
Abstract Low birthweight (LBW) is a worldwide problem that particularly affects developing countries. However, limited information available on its magnitude in rural area of Burkina Faso. This study aimed to estimate the prevalence low and identify associated factors Nanoro health district. A secondary analysis data collected during cross-sectional survey was conducted assess demographic surveillance system (HDSS). Maternal characteristics extracted from antenatal care books or by...
Abstract Background: The immunological shift occurring in pregnant women is crucial for the outcome of pregnancy. We conducted a study living malaria endemic area to determine potential effect gestational age on modulating immune system by cortisol and prolactin production. Methods: Primigravidae multigravidae with between 16-20 weeks were included followed up delivery 6-7 thereafter. Venous blood was collected at scheduled visit: Visit1 (V1; amenorrhea), Visit2 (V2; 28 ±1 pregnancy), Visit3...
Distribution of IL-10 and sTNF-RII in malaria infected versus uninfected women during pregnancy. (PDF 36Â kb)
Abstract Background. In sub-Saharan Africa, the intermittent preventive treatment of malaria in pregnancy using sulphadoxine pyrimethamine (IPTp-SP) strategy is recommended to limit adverse effects on birth outcomes. Ten year after IPTp-SP was adopted Burkina Faso, we assessed magnitude and maternal factors low birthweight (LBW) Nanoro. Methods . A secondary analysis data from a cross-sectional study carried out women who gave at Nanoro peripheral health centers binary multivariate logistic...