A5064240250- Bacterial Genetics and Biotechnology
- Escherichia coli research studies
- Antibiotic Resistance in Bacteria
- Laser Material Processing Techniques
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- 3D Printing in Biomedical Research
- Cellular Mechanics and Interactions
Boston University
2017-2019
Enteric Escherichia coli survives the highly acidic environment of stomach through multiple acid resistance (AR) mechanisms. The most effective system, AR2, decarboxylates externally-derived glutamate to remove cytoplasmic protons and excrete GABA. first described AR1, does not require an external amino acid. Its mechanism has been determined. regulation AR systems their coordination with broader cellular metabolism fully explored.We utilized a combination ChIP-Seq gene expression analysis...
Cell migration, critical to numerous biological processes, can be guided by surface topography. Studying the effects of topography on cell migration is valuable for enhancing our understanding directional and functionally engineering behavior. However, fabrication limitations constrain studies geometries that may not adequately mimic physiological environments. Direct Laser Writing (DLW) provides necessary 3D flexibility control create well-defined waveforms with curvature length scales are...