A5100641509- Liver Disease Diagnosis and Treatment
- Natural Compounds in Disease Treatment
- Allergic Rhinitis and Sensitization
- Hematopoietic Stem Cell Transplantation
- Monoclonal and Polyclonal Antibodies Research
- Natural product bioactivities and synthesis
- Lipid metabolism and disorders
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- CAR-T cell therapy research
- Protein Degradation and Inhibitors
- Renin-Angiotensin System Studies
- Redox biology and oxidative stress
- Biological Activity of Diterpenoids and Biflavonoids
- Adipose Tissue and Metabolism
- Lanthanide and Transition Metal Complexes
- Rheumatoid Arthritis Research and Therapies
- Injury Epidemiology and Prevention
- Healthcare and Venom Research
- Studies on Chitinases and Chitosanases
- Sinusitis and nasal conditions
- Acute Myocardial Infarction Research
- Salivary Gland Disorders and Functions
- Hydrogen's biological and therapeutic effects
- Advanced Proteomics Techniques and Applications
Shanghai Traditional Chinese Medicine Hospital
2024
Zhongnan Hospital of Wuhan University
2023
Wuhan University
2023
Xiangya Hospital Central South University
2009-2022
Central South University
2009-2022
Chengdu University of Traditional Chinese Medicine
2022
Guangdong Work Injury Rehabilitation Hospital
2014-2022
Kleijnen Systematic Reviews (United Kingdom)
2022
East China Normal University
2020
Guangdong Provincial People's Hospital
2008-2020
Long non-coding RNAs (lncRNAs) are known to play crucial roles in nonalcoholic fatty liver disease (NAFLD). This research sought explore mechanisms by which lncRNA MALAT1 regulates the progression of NAFLD. Thus, order detect function NAFLD, vitro and vivo model NAFLD were established. Then, acid uptake triglyceride level investigated BODIPY labeled-fatty assay Oil red O staining, respectively. The expressions MALAT1, miR-206, ARNT, PPARα CD36 detected western blotting qPCR. Dual luciferase,...
Background Obesity has reached epidemic proportions, affecting more than one tenth of the world’s population. As such, adipose tissue is being increasingly recognized as an important therapeutic target for obesity and related metabolic disorders. While many potential targets have been established drugs developed, very few those specifically without other tissue. This results from a limited knowledge both cell-surface markers physicochemical traits specific to adipocytes that might otherwise...
Nowadays, the most wildly used regimens for graft-versus-host disease (GvHD) prophylaxis in haplo-hematopoietic stem cell transplantation (Haplo-HSCT) are based on vivo T-cell depletion (TCD) with anti-thymocyte globulin (ATG) or posttransplant cyclophosphamide (PTCy). To improve efficiency of GvHD haploidentical peripheral blood combined unrelated cord (Haplo-PBSCT-Cord), a novel regimen, which is composed low dose ATG (5 mg/kg) and low-dose PTCy (50 prophylaxis, was evaluated prospective...
Anterior cruciate ligament (ACL) injury can cause damage to the meniscus and articular cartilage, may even lead osteoarthritis. This study aimed analyze accuracy feasibility of magnetic resonance imaging (MRI) signs in diagnosis knee joint ACL injury.A total 78 patients admitted our hospital from June 2018 October 2019 with highly suspected were selected for this prospective study. We used MRI arthroscopy diagnose injuries, results arthroscopy, as well value diagnosing injury, compared.Among...
Abstract Background Atherosclerosis and thrombosis play important roles in the pathophysiology of acute coronary syndrome, with platelet activation inflammation as key initiative factors. Recently mean volume-to-lymphocyte ratio (MPVLR) monocyte to high-density lipoprotein cholesterol (MHR) have emerged new prognostic indicators cardiovascular diseases. However, predicting effect combination MPVLR MHR myocardial infarction has not been reported. Objective The aim this study was investigate...
Abstract The epithelial cell adhesion molecule (EpCAM) is closely correlated with the occurrence and development of various cancers origin. This study tested, for first time, ability EpCAM aptamer SYL3C to detect expression in 170 cases esophageal cancer (EC) precancerous lesions, as well 20 EC series samples, using immunofluorescence imaging analysis. Corresponding antibodies were used control. overexpression was 98% both squamous carcinoma (ESCC) adenocarcinoma (EACA) 100% metastasis, but...
Chimeric antigen receptor T cells (CAR T) targeting CD7 for T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) showed promising efficacy and safety in some clinical trials. However, most of them were bridged with allogeneic hematopoietic stem cell transplantation (allo-HSCT). We described successful treatment preventive donor-derived anti-CD7 CAR-T therapy a case refractory lymphoma following allo-HSCT, who could not receive autologous products due to the low-quality lymphocytes. To...
To understand the epidemiological characteristics of workers who are burn patients, and to provide basis for prevention treatment at work.We investigated 4 078 in 9 cities Hunan provincial enterprises, different trades managed by municipal government from January 1st, 2005 December 31st, 2010.The incidence rate employment injury was 94.84 per 10 thousand each year Hunan. That enterprises directly Medical Insurance Bureau 93.71 year, that Bureaus or districts 95.02 year. The accounted 2.00%...
Objective To investigate the relationship between insulin resistance index (HOMA-IR) and clinical pathology fea-tures in chronic hepatitis B(CHB) patients. Methods ALT B virus loading level HOMA-IR were measured 80 CHB pa-tients. Correlation analysis was performed with pathological features of liver tissue. Result Insulin resistance(IR) much more obvious patients severer degree inflammation fibrosis . G3 grade(15.24±7.41,3.51 ± 1.91) S3 stage (16.65±6. 46,3.79 1.50) higher than those G2...