A5070400066- Insect and Pesticide Research
- Coal and Its By-products
- Insect and Arachnid Ecology and Behavior
- Heavy metals in environment
- Plant and animal studies
- Autophagy in Disease and Therapy
- Viral Infections and Outbreaks Research
- Advanced Photocatalysis Techniques
- Gut microbiota and health
- Vibrio bacteria research studies
- Viral Infections and Vectors
- Concrete Corrosion and Durability
- Viral gastroenteritis research and epidemiology
- Insect-Plant Interactions and Control
- Geochemistry and Geologic Mapping
- RNA Interference and Gene Delivery
- Mercury impact and mitigation studies
- Polymer composites and self-healing
- Clostridium difficile and Clostridium perfringens research
- Iron oxide chemistry and applications
- Corrosion Behavior and Inhibition
- Urinary Tract Infections Management
- Advanced Battery Technologies Research
- Quantum Dots Synthesis And Properties
- Recycling and utilization of industrial and municipal waste in materials production
Yunnan Academy of Agricultural Sciences
2020-2024
Institute of Apiculture Research
2024
Tianjin Medical University
2019-2024
State Grid Corporation of China (China)
2021-2024
Second Hospital of Tianjin Medical University
2023-2024
Systems Engineering Society of China
2021-2022
Sericultural Research Institute
2021
Chinese Academy of Sciences
2012-2017
Shanghai Institute of Applied Physics
2015-2017
University of Missouri
2014-2016
In this work, a higher concentration of Ti ions are incorporated into hydrothermally grown Ti-doped (2.2% by atomic ratio) micro-nanostructured hematite films an in situ solid-state reaction method. The doping is improved from 2.2% to 19.7% after the reaction. X-ray absorption analysis indicates substitution Fe ions, without generation Fe2+ defects. Photoelectrochemical impedance spectroscopy reveals dramatic improvement electrical conductivity film As consequence, photocurrent density...
Members of the interferon-induced transmembrane (IFITM) protein family inhibit entry a wide range viruses. Viruses often exploit endocytosis pathways to invade host cells and escape from endocytic vesicles in response low pH. Localization these is essential for IFITM3 interfere with cytosolic pH-dependent However, nature sorting signal that targets poorly defined. In this study, we report possesses YxxΦ motif, i.e. 20-YEML-23, enables undergo through binding μ2 subunit AP-2 complex....
Tryptophan and its derivatives perform a variety of biological functions; however, the role specific mechanism many tryptophan in intestinal inflammation remain largely unclear. Here, we identified that an Escherichia coli strain ( Ec- TMU) isolated from feces tinidazole-treated individuals, indole-3-lactic acid (ILA) supernatant, decreased susceptibility mice to dextran sulfate sodium–induced colitis. TMU ILA contribute relief colitis by inhibiting production epithelial CCL2/7, thereby...
Iron(III) oxide photoelectrodes show promise in water oxidation applications. In this study, micro-nano-structured hematite films are synthesized, and Ti ions doped to improve photoelectric conversion efficiency. The photocurrent increases for enhanced electrical conductivity. Further is achieved Fe2O3:Ti/ZnFe2O4 heterojunction electrodes. Cyclic voltammograms combined with optical absorbance examinations demonstrate that the conduction valence band edges of ZnFe2O4 shift from those Fe2O3...
Significance TIM-family proteins have been recently shown to promote viral entry into host cells. Unexpectedly, we discovered that human TIM-1, along with TIM-3 and TIM-4, potently inhibits HIV-1 release. We showed TIM-1 is incorporated virions retains particles on the plasma membrane via phosphatidylserine (PS), a phospholipid exposed cellular envelope. Expression of replication in CD4 + T cells, knockdown monocyte-derived macrophages enhances production. extended this function TIMs other...
Abstract Background The pathogenesis of inflammatory bowel diseases (IBD) is multifactorial, and diagnostic treatment strategies for IBD remain to be developed. RhoB regulates multiple cell functions; however, its role in colitis unexplored. Results Here, we found was dramatically increased colon tissues ulcerative (UC) patients mice with DSS-induced colitis. Compared wild type mice, +/− −/− developed milder goblet numbers IEC proliferation. Decreased promoted differentiation epithelial...
The soil contamination caused by the discharge of cadmium (Cd) from coal mining activities has aroused continuous attention due to detrimental effects on human health. This study aimed investigate characteristics distribution Cd in soils and its accumulation wheat grains under wheat-cultivation system, further assess health risks adults children. 58 samples pairs Linhuan area, Anhui Province were collected analyzed. Results showed that concentrations 17.24% exceeded limit value established...
This paper presents a facile route to prepare CuInS2 (CIS) as light absorber for solar cells. CIS was effectively deposited inside the pores of nanoporous anatase titanium dioxide photoelectrodes with high coverage degree. The performance CIS-sensitized TiO2 could be substantially enhanced through sequential coating CdS shell and ZnS layer via successive ionic adsorption reaction (SILAR). Electrochemical impedance spectrum (EIS), cyclic voltammetry (CV), photocurrent experiments were...
Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections (UTIs), inducing acute pyelonephritis and may result in permanent renal scarring failure. Alpha-hemolysin (HlyA), a key UPEC toxin, causes serious tissue damage; however, mechanism through which HlyA induces kidney injury remains unclear. In present study, granulocyte-macrophage colony-stimulating factor (GM-CSF) secreted by epithelial cells was upregulated vitro vivo, induced M1 macrophage accumulation...
Ebola virus (EBOV) is a highly pathogenic filovirus that causes hemorrhagic fever in humans and animals. Currently, how EBOV fuses its envelope membrane within an endosomal to cause infection poorly understood. We successfully measure cell-cell fusion mediated by the protein, GP, assayed transfer of both cytoplasmic dyes. A small molecule inhibitor, neutralizing antibody, as well mutations GP known reduce viral infection, all greatly fusion. By monitoring redistribution aqueous dyes between...
HSPA8 (heat shock protein family A (Hsp70) member 8) plays a significant role in the autophagic degradation of proteins, however, its effect on stabilization and anti-bacterial autophagy remains unknown. Here, it is discovered that HSPA8, as binding partner RHOB BECN1, induce for intracellular bacteria clearance. Using NBD LID domains, physically binds to residues 1–42 89–118 well BECN1 ECD domain, preventing degradation. Intriguingly, contains predicted intrinsically disordered regions...
The interferon-induced transmembrane proteins (IFITMs) broadly inhibit virus infections, particularly at the viral entry level. However, despite this shared ability to fusion, IFITMs differ in potency and breadth of viruses restricted, an anomaly that is not fully understood. Here, we show differences range restricted by IFITM1 are regulated a C-terminal non-canonical dibasic sorting signal KRXX suppresses restriction some governing its intracellular distribution. Replacing two basic...
Abstract Host cells use several anti-bacterial pathways to defend against pathogens. Here, using a uropathogenic Escherichia coli (UPEC) infection model, we demonstrate that bacterial upregulates RhoB, which subsequently promotes intracellular bacteria clearance by inducing LC3 lipidation and autophagosome formation. RhoB binds with Beclin 1 through its residues at 118 140 the CCD domain, Arg133 being key binding residue. Binding of enhances Hsp90-Beclin interaction, preventing degradation....