A5068631935- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- Immune Response and Inflammation
- Hepatitis B Virus Studies
- SARS-CoV-2 and COVID-19 Research
- Advanced biosensing and bioanalysis techniques
- Advanced Drug Delivery Systems
- Advanced Sensor and Energy Harvesting Materials
- Agriculture Sustainability and Environmental Impact
- Antimicrobial Peptides and Activities
- Bacteriophages and microbial interactions
- Synthesis and Properties of Aromatic Compounds
- Climate change impacts on agriculture
- Immune responses and vaccinations
- Diabetes and associated disorders
- Escherichia coli research studies
- Quantum Dots Synthesis And Properties
- Advanced Battery Technologies Research
- Advanced Materials and Mechanics
- Coagulation and Flocculation Studies
- FOXO transcription factor regulation
- Connective Tissue Growth Factor Research
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- Fiber-reinforced polymer composites
Dalian University of Technology
2019-2025
Chinese University of Hong Kong
2024-2025
Dalian University
2019-2024
Zhongnan University of Economics and Law
2024
Huazhong Agricultural University
2024
University of Florida
2024
First Affiliated Hospital of Jiamusi University
2021-2022
Jiamusi University
2022
Dongguan University of Technology
2015-2022
Tianjin University of Science and Technology
2017
Virus-like particles (VLPs) are self-assembled viral proteins that represent a superior form of antigens in vaccine formulations. To enhance immunogenicity, adjuvants, especially the aluminum salts (Alum), essentially formulated VLP vaccines. However, Alum only induce biased humoral immune responses limits further applications VLP-based stimulate more balanced immunity, we, herein, develop one-step strategy using VLPs as biotemplates to synthesize raspberry-like silica-adjuvanted VLP@Silica...
Abstract Emerging therapies rely on the efficient and specific delivery of targeted agents into cytosol, such as DNA, siRNA proteins. Nanoparticles showed great potentials in safe transportation cargoes; however, entrapment endosomes degradation by enzymes lysosome hindered bioavailability, cytosolic subsequent therapeutic efficacy. In this case, development methods for focuses overcoming major challenge endo/lysosomal escape, which relies nano‐delivery systems. A deeper mechanistic...
The interaction between the aluminum salt-based adjuvants and antigen in vaccine formulation is one of determining factors affecting immuno-potentiation effect vaccines. However, it not clear how intrinsic properties could affect this interaction, which limits to benefit improvement existing further new Here, we engineered oxyhydroxide (AlOOH) nanorods used a variety antigens including hepatitis B surface (HBsAg), SARS-CoV-2 spike protein receptor-binding domain (RBD), bovine serum albumin...
Endohedral metallofullerenes (EMFs) are one type of intriguing metal/carbon hybrid molecule with the configuration sphere cavity-encapsulating metal ions/metal clusters due to their unique physicochemical properties and corresponding application in fields biological materials, single magnet materials energy conversion materials. Although EMF family is growing, versatile EMFs have been successfully synthesized confirmed using crystal structures, some expected members not observed conventional...
Hydroxyapatite (HAP) has been formulated as adjuvants in vaccines for human use. However, the optimal properties required HAP nanoparticles to elicit adjuvanticity and underlying immunopotentiation mechanisms have not fully elucidated. Herein, a library of nanorods nanospheres was synthesized explore effect particle shape aspect ratio on immune responses vitro vivo. It demonstrated that long induced higher degree cell membrane depolarization subsequent uptake, internalized particles elicited...
Abstract Climate-smart agriculture is guided by three main goals: increased productivity, enhanced resilience (climate change adaptation), and reduced emissions mitigation). Early mature crop varieties have been promoted to minimize the impact of climate extreme weather events on farming activities. This study examined effects adopting early rice agricultural adaptation, mitigation. Data came from a cross-sectional sample 1396 farmers in Hubei, China. Productivity was measured via mean...
Abstract The practice of straw return represents an effective and sustainable approach to recycling reusing agricultural residues, thereby significantly contributing the circular economy within agri‐food sector. Although this holds significant promise for enhancing soil quality mitigating pollution resulting from burning, realization these substantial benefits depends on extent which farmers are willing embrace practice, a decision closely tied anticipated economic it offers. present study...
The handsheets of an alkaline battery separator were made polypropylene (PP) fibers and polyethylene/polypropylene bicomponent sheath-core structure (EP) in the wet-laid process followed by a hot-pressing treatment. effects parameters making on formation resultant tensile strength, maximum pore size, porosity, alkali resistance investigated. results showed that favorable could be obtained at EP addition level not less than 20%. In addition, 60% PP 40% meet needs required QB/T 4173 (2011),...