- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Neurological Disorders and Treatments
- Atrial Fibrillation Management and Outcomes
- Cognitive Abilities and Testing
- Education and Critical Thinking Development
- Educational and Psychological Assessments
- Education, Achievement, and Giftedness
- Peripheral Artery Disease Management
- Intracranial Aneurysms: Treatment and Complications
- Career Development and Diversity
- Vascular Anomalies and Treatments
- Health Literacy and Information Accessibility
- Education Systems and Policy
- Social Media in Health Education
- Diverse Educational Innovations Studies
- Ophthalmology and Eye Disorders
- Early Childhood Education and Development
- Lipoproteins and Cardiovascular Health
- Social and Intergroup Psychology
- Academic Freedom and Politics
University at Buffalo, State University of New York
2011-2023
Colby–Sawyer College
2020
New York University
2018
Kaleida Health
2014
Duke University
1979-1988
Missouri University of Science and Technology
1968-1974
Wyoming Department of Education
1967
University of Wyoming
1967
<h3>Importance</h3> More than half of patients with acute ischemic stroke have minor neurologic deficits (National Institutes Health Stroke Scale [NIHSS] score 0-5) at presentation. Although prior major trials alteplase included low NIHSS scores, few without clearly disabling were enrolled. <h3>Objective</h3> To evaluate the efficacy and safety in scores 0 to 5 whose are not disabling. <h3>Design, Setting, Participants</h3> The PRISMS trial was designed as a 948-patient, phase 3b,...
Agonism of protease-activated receptor (PAR) 1 by activated protein C (APC) provides neuro- and vasculoprotection in experimental neuroinjury models. The pleiotropic PAR1 agonist, 3K3A-APC, reduces neurological injury promotes vascular integrity; 3K3A-APC proved safe human volunteers. We performed a randomized, controlled, blinded trial to determine the maximally tolerated dose (MTD) ischemic stroke patients.
Intracranial aneurysms are currently considered as contraindication for intravenous thrombolysis in acute ischemic stroke, very likely due to a possible increase the risk of bleeding from aneurysm rupture; however, there is limited data available on whether safe stroke patients with pre-existing intracranial aneurysms.To find out safety who harbor unruptured aneurysms.We retrospectively reviewed medical records and cerebrovascular images all treated our center beginning 2006 till end April...
The NINDS trial demonstrated the efficacy of intravenous (IV) recombinant tissue plasminogen activator (rtPA) in improving neurologic outcome patients presenting with acute ischemic strokes. Patients who had a prior history intracranial hemorrhage (ICH) were excluded from this trial, possibly due to hypothetical increase subsequent bleeding risk. Thus, there is little data available, whether against or favor of, use IV rtPA ICH. We aim aid determining safety such through retrospective...
<b><i>Aim:</i></b> The aim of this was to study the effects statins and their intensity on symptomatic intracranial hemorrhage (sICH) outcome after IV thrombolysis (IVT) for acute ischemic stroke (AIS). <b><i>Methods:</i></b> We retrospectively reviewed medical records cerebrovascular images all patients treated with IVT AIS in our center a 10-year period. Patients were further characterized as any statin users versus non-users admission...
Common causes of oculomotor nerve palsy are diabetes, aneurysmal compression, and uncal herniation. A lesser-known cause third dysfunction is ischemia, often due to carotid artery dissection.An 80-year-old man presented with an acute ischemic stroke a National Institutes Health Stroke Scale score >20 from high cervical internal (ICA) dissection tandem ICA terminus embolic occlusion extension clot into the adjacent fetal posterior cerebral (PCA). We used stentriever perform selective PCA...
<b><i>Background:</i></b> We sought to investigate the effect of obesity and BMI on functional outcome rate symptomatic intracranial hemorrhage (sICH) in a large sample patients with acute ischemic stroke (AIS) treated intravenous thrombolysis (IVT). <b><i>Methods:</i></b> In single-center retrospective, but prospectively collected data, study AIS IVT 10-year period, were placed into groups based their defined as underweight (&#x3c;18.5...
Cerebral edema is a secondary complication of acute ischemic stroke, but its time course and imaging markers are not fully understood. Recently, net water uptake (NWU) has been proposed as novel marker edema.
Prior studies indicate that the human translational vestibulo‐ocular reflex (tVOR) generates eye rotations approximately half magnitude required to keep line of sight pointed at a stationary object—a compensation ratio (CR) ∼0.5. We asked whether changes visual or vestibular stimuli could increase CR tVOR. First, subjects viewed their environment through an optical device movements by ∼50% maintain fixation target. During vertical translation, did increase, but tVOR remained Second, LCD...
Concurrent validity of the French Pictorial Test Intelligence (PTI) was Investigated using kindergarten ant second-grade students. At and levels, respectively, correlations with criteria employed were: WISC Full Scale .75, .71; Verbal .64, .66; Performance .66, .69; Lorge Thorndike .51. .42; teachers’ estimation IQ .85, .46. Generally, ability PT to predict students’ class grades at both grade levels reading skills, level, as measured by Stroud Hieronymus Test, poor.Intereorrelations between...
Safety of intravenous thrombolysis (IVT) within 3-4.5 hours stroke onset in patients ≥80 years is still disputable. We evaluated the association symptom onset-to-treatment time (SOTT) with symptomatic intracranial hemorrhage (sICH), poor outcome, and mortality patients≥80 years.In a retrospective study, treated IVT following were registered. Outcomes outcome (mRS>2), sICH/ECASS-2, in-hospital mortality. compared who received 3 those receiving hours. further <80 SOTT hours.Of 834 patients,...
The Duke University Precollege Program, Summer Residential Program for Verbally and Mathematically Precocious Youths, the By‐Mail Commuter Programs are reviewed. These offerings allow brilliant young students to plan a multi‐summer program beginning in summer prior grade 8 culminating senior year high school. residential life activities relationship with parochial, private, public schools teachers is explored.
AbstractNinety beginning freshmen at the University of Missouri-Rolla were utilized as subjects. The sample was sub-divided into three equal groups; experimental group composed pre-registered students enrolled in an intensified instructional program Study Skills and Developmental Reading provided specialized counseling services; one control that had taken part pre-registration UMR, but not instruction other accorded no variation traditional method enrollment or instruction. All groups...
The investigation was conducted to determine what, if any, differences in expectations, motivations, satisfaction, and performance existed among 612 extremely gifted adolescents attending the Talent Identification Program's Summer Residential Program. As part of a thorough program evaluation, staged series statistical analyses were effected. Three discernible groups students emerged (Academically Oriented, Socially Highly Motivated-Gregarious). Investigation composition correlates these...