- Breast Cancer Treatment Studies
- Immune cells in cancer
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- Inflammation biomarkers and pathways
- Gastric Cancer Management and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Cancer Diagnosis and Treatment
- Cancer Cells and Metastasis
- Ovarian cancer diagnosis and treatment
- Chemokine receptors and signaling
- Gastrointestinal disorders and treatments
- Retinoids in leukemia and cellular processes
- Metastasis and carcinoma case studies
- Psoriasis: Treatment and Pathogenesis
- Multiple and Secondary Primary Cancers
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Advances in Oncology and Radiotherapy
- Advanced Biosensing Techniques and Applications
- Lung Cancer Treatments and Mutations
- HER2/EGFR in Cancer Research
- Reconstructive Surgery and Microvascular Techniques
- Cancer, Stress, Anesthesia, and Immune Response
- Radiomics and Machine Learning in Medical Imaging
Medical University of Lublin
2015-2025
University of Opole
2022
University of Warmia and Mazury in Olsztyn
2022
Breast Center
2013
Agaplesion Markus Hospital
2013
Kantonsspital Baden
2013
Engeriedspital
2013
Abstract Myeloid-derived suppressor cells (MDSC) contribute to immune suppression in cancer, but the mechanisms through which they drive metastatic progression are not fully understood. In this study, we show how MDSC convey stem-like qualities breast cancer that coordinately help enable and escape. We found promoted tumor formation by enhancing cell properties as well suppressing T-cell activation. Mechanistic investigations indicated these effects relied upon cross-talk between STAT3 NOTCH...
Sentinel lymph node biopsy (SLNB) is the standard surgical procedure for axilla in early node-negative breast cancer. To date, "gold standard" to localize sentinel (SLN) radiotracer (99m)Tc with or without blue dye. The aim of this study was evaluate potential equivalency new SentiMag(®) technique comparison standard". Within prospective, multicentric and multinational non-inferiority including 150 patients compared magnetic technique, using superparamagnetic iron oxide particles (SPIOs,...
The purpose of this study was to evaluate the feasibility and safety indocyanine green (ICG) fluorescence as an alternative traditional sentinel lymph node biopsy (SLNB) techniques in breast cancer (BC) patients undergoing neoadjuvant chemotherapy (NAC). Specifically, aimed assess identification rates effectiveness ICG axillary staging without use radioactive tracers. This retrospective included 71 BC treated with NAC, who underwent SLNB using between 2020 2024. injected intradermally around...
The ratio of positive lymph nodes (LNs) to the total LN harvest is called (LNR). It an independent prognostic factor in gastric cancer (GC). aim current study was evaluate impact neoadjuvant chemotherapy (NAC) on LNR (ypLNR) patients with advanced GC. We retrospectively analysed data GC, who underwent gastrectomy N1 and N2 (D2) lymphadenectomy between August 2011 January 2019 Department Surgical Oncology at Medical University Lublin. exclusion criteria were a lack preoperative NAC...
Introduction:The aim of this study was to present a new predictive tool for non-sentinel lymph node (nSLN) metastases.Material and methods: One thousand five hundred eighty-three patients with early-stage breast cancer were subjected sentinel biopsy (SLNB) between 2004 2012.Metastatic SLNs found in 348 -the retrospective group.Selective axillary dissection (ALND) performed 94% cases.Involvement the nSLNs identified 32.1% following ALND.The correlation nSLN involvement selected...
Peritoneal metastases (PM) of gastric cancer (GC) are characterized by a particularly poor prognosis, with median survival time 6 months, and virtually no 5-year reported. Conversion therapy for GC is defined as surgical treatment aiming at an R0 resection after systemic chemotherapy tumours that were originally unresectable (or marginally resectable) technical and/or oncological reasons. The aim the present study was to evaluate early late outcomes in patients PM who underwent cytoreductive...
The standard method for nodal staging in breast cancer (BC) patients after neoadjuvant chemotherapy (NAC) is sentinel lymph node biopsy (SLNB) with a radioisotope (RI) injection. However, SLNB NAC results high false-negative rates (FNR), and the RI restricted by nuclear medicine unit dependency. These limitations resulted development of superparamagnetic iron oxide (SPIO) method, reducing FNR presenting comparable detection rate. This bi-institutional cohort comparison study aimed to assess...
Sentinel lymph node biopsy (SLNB) is a well-established procedure for staging clinically node-negative early breast cancer (BC). Superparamagnetic iron oxide (SPIO) demonstrated efficacy nodal identification using magnetic probe after local retroaeroal interstitial injection. Its benefits lie in its flexibility, which an essential property the global setting, where access to isotope difficult. To best of our knowledge, this first study evaluate feasibility and safety SPIO SLNB BC patients...
The erector spinae plane (ESP) block has recently been shown to effectively alleviate postoperative pain and reduce opioid consumption in breast surgery patients. However, data are still limited concerning the quality of recovery patients following this procedure.This study was a randomized controlled trial (RCT) performed university hospital. We randomly allocated one three groups: ESP, SHAM, control (CON). Procedures ESP SHAM blocks were ipsilaterally with 0.375% ropivacaine or 0.9% saline...
Proximal gastric resection (PGR) is rarely used in western countries because of frequent postoperative reflux and uncommon diagnosis early cancer (GC).We hypothesized that the PGR with an anti-reflux procedure may be attractive option even advanced proximal GC after downstaging neo-adjuvant chemotherapy.A novel technique end-to-side esophago-gastrostomy posterior wall stump partial neo-fundoplication to prevent symptoms has been introduced. An observational retrospective study was undertaken...
AMA Sitarz R, Skierucha M, Jazienicki et al. Lipomas – a health condition that cannot be ignored. Family Medicine & Primary Care Review. 2016;18(4):473-476. doi:10.5114/fmpcr.2016.63704. APA Sitarz, R., Skierucha, M., Jazienicki, Kurylcio, A., Wierzbicki, Maciejewski, R. (2016). Review, 18(4), 473-476. https://doi.org/10.5114/fmpcr.2016.63704 Chicago Robert, Małgorzata Mieczysław Andrzej Ryszard and Wojciech P. Polkowski. 2016. "Lipomas ignored". Review 18 (4): Harvard Polkowski, W....
Oncoplastic and reconstructive techniques are essential tools in the armamentarium of contemporary breast surgeons. The aim study was to identify oncoplastic patterns cancer centers across Poland. A questionnaire 18 questions sent by email members Polish Society Surgical Oncology Plastic, Reconstructive Esthetic Surgery via their dedicated websites. numbers patients operated on each center ranged from 120 904 per year. Breast-conserving surgery (BCS) predominated all but one (range 50-70%)....
Pancreas divisum (PD) is the most common congenital anomaly of pancreas, which increases susceptibility to recurrent pancreatitis. Usually, after failure initial endoscopic therapies, surgical treatment combining pancreatic resection or drainage used. The Frey procedure used for chronic pancreatitis, but it has not been reported be applied in an adult patient with PD-associated purpose paper was describe effective this rare condition by interventional treatment. A 39-year-old female...
Introduction: The role of surgery in stage IV gastric cancer with peritoneal metastasis (PM) remains unclear. objective the current single-center study was to define impact gastrectomy cytoreductive (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) on outcomes among Central European GC patients limited disease progression after neoadjuvant (NAC). Methods: Patients histologically confirmed who underwent curative-intent multimodal treatment between 2013 2023 were included. without...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Mielko J, Kurylcio A, Skórzewska M, et al. Duodenal obstruction due to annular pancreas associated with carcinoma of the duodenum. Gastroenterology Review/Przegląd Gastroenterologiczny. 2016;11(2):139-142. doi:10.5114/pg.2016.57885. APA Mielko, J., Kurylcio, A., Skórzewska, M., Ciseł, B., Polkowska, & Rawicz-Pruszyński, K. (2016). Gastroenterologiczny, 11(2), 139-142. https://doi.org/10.5114/pg.2016.57885...
Recently, the potential risk of malignant skin cancer development in psoriatic patients has been highlighted. It seems that some pathogenetic factors psoriasis could predispose to a transformation. So far, relationship between therapeutic schemes and possible neoplastic transformation not clearly explained. The phototherapy is considered very effective method psoriasis, however, pathogenesis malignancies associated with exposure UV radiation. One defence mechanisms protect cells from...