A5100854551- Natural product bioactivities and synthesis
- Photosynthetic Processes and Mechanisms
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Plant Parasitism and Resistance
- Sesquiterpenes and Asteraceae Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Plant biochemistry and biosynthesis
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Allelopathy and phytotoxic interactions
- Plant and animal studies
- Plant Toxicity and Pharmacological Properties
- Ethnobotanical and Medicinal Plants Studies
- Water Resource Management and Quality
- Accounting and Financial Management
- Phytochemical compounds biological activities
- Plant chemical constituents analysis
- Mass Spectrometry Techniques and Applications
- Protein purification and stability
- Traditional and Medicinal Uses of Annonaceae
- Mitochondrial Function and Pathology
- Synthesis and biological activity
- Fungal Biology and Applications
- Chemical Synthesis and Analysis
Universidad Nacional Autónoma de México
2007-2024
Hospital Universitario de Valme
2021-2023
Austral University of Chile
2021
Monash University
1992-2001
Hospital de Especialidades
2000
Centro Medico Nacional Siglo XXI
2000
Universidad Autónoma del Estado de Morelos
1998
Mexican Social Security Institute
1998
The University of Melbourne
1984-1988
Tagetes lucida Cav. (Asteraceae) is an ancient medicinal plant commonly used to alleviate pain. Nevertheless, scientific studies validating this property are lacking in the literature. Animal models of pain were evaluate antinociceptive and anti-inflammatory activities T. essential oil (TLEO) a bioactive metabolite. The chemical constitution possible toxicity extract mechanism action β-caryophyllene also explored. Temporal course curves dose–response graphics generated using TLEO (0.1–10...
The n-hexane extract of S. salignus plants inhibited ATP synthesis and two sesquiterpenes, the β-caryophyllene (1) caryophyllene oxide (2) were isolated from this nonpolar fraction. Compound 1 by 42% root elongation Physalis ixocarpa seedlings at 50 µg/mL 53% 150 µg/mL, whereas compound only Echinochloa crus-galli 30%. On other hand, 2 had no effect on either germination or stem growth E. cruss galli P. ixocarpa. However, dry biomass grown for 18 days previous to treatment it was found that...
Through bioactivity-guided chemical analysis of Selaginella lepidophylla, biflavonoids robustaflavone (1), 2,3-dihydrorobustaflavone (2), and 2,3-dihydrorobustaflavone-5-methyl ether (3) were isolated their structures confirmed by spectroscopic spectrometric analyses. Their NMR resonances unambiguously assigned from HMBC, NOESY, NOESY-1D experiments, absolute configurations 2 3 established. Compound has not been reported, although structure was described before, the (13)C assignment does...
Two new cytotoxic isoflavans, (3S)-7-hydroxy-2',3',4',5', 8-pentamethoxyisoflavan (1) and (3S)-3',7-dihydroxy-2',4',5', 8-tetramethoxyisoflavan (2), were isolated from the bark trunks of Eysenhardtia polystachya (Leguminosae), together with known constituents stigmasterol, isoduartin, cuneatin, 7-hydroxy-2',4', 5'-trimethoxyisoflavone, 3,4-dimethoxy-8, 9-(methylenedioxy)pterocarpan. The structures 1 2 elucidated on basis spectroscopic methods. antimicrobial, cytotoxic, insecticidal potential...
A bioactivity-guided chemical study of aerial parts Croton ciliatoglanduliferus Ort. led to the isolation for first time flavonoids retusin (5-hydroxy-3,7,3',4'-tetramethoxyflavone) (1) and pachypodol (5,4'-dihydroxy-3,7,3'-trimethoxyflavone) (2) from n-hexane extract. Compounds 1 2 were separated by preparative thin-layer chromatography. Compound was most active compound on ATP synthesis inhibition. The I50 value 51 μM. Pachypodol behaves as a Hill reaction inhibitor. It inhibited uncoupled...
Flavonoids retusin (5-hydroxy-3,7,3',4'-tetramethoxyflavone) (1) and pachypodol (5,4'-dihydroxy-3,7,3'-trimethoxyflavone) (2) were isolated from Croton ciliatoglanduliferus Ort. Pachypodol acts as a Hill reaction inhibitor with its target on the water splitting enzyme located in PSII. In search for new herbicides natural compounds, flavonoids 1 2 flavonoid analogues quercetin (3), apigenin (4), genistein (5), eupatorin (6) assessed their effect vitro photosynthetic electron transport chain...
Three compounds were isolated from Maytenus acanthophylla Reissek (Celastraceae): the pentacyclic triterpenes lup-20(29)-en-3β-ol (lupeol, 1) and 3β-lup-20(29)-en-3-yl acetate (2) carbohydrate 1,2,3,4,5,6-hexa-O-acetyldulcitol (3); lupeol was also Xylosma flexuosa. The compounds’ structures elucidated by spectroscopic spectrometric analysis. Compound 1 acts as an energy transfer inhibitor, interacting with CF1 bound to thylakoid membrane, dulcitol hexaacetate 3 behaves a Hill reaction...
The main objective of treatment against hypertension is not only to reduce blood pressure levels, but also vascular risk in general. In the present work, administering angiotensin II (AGII; 0.2 µg/kg intraperitoneally (i.p.) for 12 weeks) activates hypothalamic-pituitary-adrenal (HPA) axis, which caused an increase corticosterone as well proinflammatory cytokines (interleukin 1β (IL-1β), interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-α)) macrophage chemotactic protein 1 (MCP-1),...
Abstract The inhibition of ATP synthesis, proton uptake and electron transport (basal, phosphory-lating uncoupled) from water to methylviologen indicates that cacalol its derivatives act as inhibitors. Since on one hand photosystem I is not affected electron DPC QA midly the other DCIP, silicomolibdate are inhibited, we conclude site located at oxygen evolution level. Cacalol inhibit flow between P680 probably also Q B site.
Abstract The novel bisabolene sesquiterpenes 3-6, were isolated from Iostephane heterophylla, using bioguided fractionation. new compounds determined to be (12R/12S)-12,13-epoxy-xanthorrhizols (3,4) and (12R/12S)-12,13-dihydro-12,13-dihydroxy-xanthorrizols (5,6) their structures characterized by analysis of spectroscopic data chemical correlation xanthorrhizol (2). stereochemistry at C-12 5 was deduced the modified Mosher experiment. Some elicited activity against gram positive negative...
The main use of stem bark infusions Alnus acuminata ssp. arguta (Schlecht.) Furlow (Betulaceae) includes treatments for acute inflammation in Mexican traditional medicine.n-Hexane (CHE), chloroform (CCE), and methanol (CME) extracts the were investigated anti-inflammatory activity its safety.The effects orally administered CME, CCE, CHE extracts, using carrageenan-induced rat hind paw edema model, oral toxicity mice, Lorke's method, determined.The column chromatographic fraction (CME-3)...