A5071818372- Nosocomial Infections in ICU
- Intracranial Aneurysms: Treatment and Complications
- Intensive Care Unit Cognitive Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Respiratory Support and Mechanisms
- Healthcare Decision-Making and Restraints
- Pneumonia and Respiratory Infections
- Cerebrospinal fluid and hydrocephalus
- Anesthesia and Sedative Agents
- Cardiac electrophysiology and arrhythmias
- Sepsis Diagnosis and Treatment
- Poisoning and overdose treatments
- Anesthesia and Neurotoxicity Research
- Migraine and Headache Studies
- Cardiovascular Syncope and Autonomic Disorders
- Rabies epidemiology and control
- Medical Device Sterilization and Disinfection
- Family and Patient Care in Intensive Care Units
- Neurosurgical Procedures and Complications
- Forensic Toxicology and Drug Analysis
- Oral microbiology and periodontitis research
- Anesthesia and Pain Management
- Infective Endocarditis Diagnosis and Management
- Neurological Complications and Syndromes
- Respiratory viral infections research
Medisch Centrum Haaglanden
2005-2022
University Medical Center Utrecht
2005
Stichting Epilepsie Instellingen Nederland
2005
Maastricht University Medical Centre
1998-2003
Maastricht University
2001
Selective digestive tract decontamination (SDD) and selective oropharyngeal (SOD) are infection-prevention measures used in the treatment of some patients intensive care, but reported effects on patient outcome conflicting.
<h3>Importance</h3> Results of studies on use prophylactic haloperidol in critically ill adults are inconclusive, especially patients at high risk delirium. <h3>Objective</h3> To determine whether improves survival among delirium, which was defined as an anticipated intensive care unit (ICU) stay least 2 days. <h3>Design, Setting, and Participants</h3> Randomized, double-blind, placebo-controlled investigator-driven study involving 1789 treated 21 ICUs, nonpharmacological interventions for...
Although recommended durations of antimicrobial therapy for ventilator-associated pneumonia (VAP) range from 7 to 21 d, these are not based on prospective studies and little is known about the resolution symptoms after start antibiotics. Resolution was investigated in 27 patients. VAP diagnosed clinical, radiographic, microbiological criteria, including quantitative cultures bronchoalveolar lavage. All patients received appropriate antibiotic therapy. Highest temperatures, leukocyte counts,...
To investigate salivary flow and frequency of oral mucositis in intensive care unit patients compared with admitted because elective coronary artery bypass graft (CABG) surgery. In addition, the pattern oropharyngeal colonization was investigated these patients.Prospective study.Mixed cardiosurgical ward.In this study, 24 ventilated 20 CABG were included.Two dental hygienists examined for presence periodontal disease at admission subsequently every week during their stay unit. At same time,...
OBJECTIVE: Current prognosticators for patients with subarachnoid hemorrhage (SAH) do not take into account signs of extracerebral organ dysfunction. This may explain the only moderate predictive value these prognosticators. We assessed prognostic simplified acute physiology score (SAPS) II in SAH patients. METHODS: In a retrospective cohort study 148 consecutive patients, we related SAPS calculated within 24 hours after admission to clinical and initial computed tomographic imaging...
Use of selective decontamination the digestive tract (SDD) and oropharyngeal (SOD) in intensive care patients has been controversial for years. Through regular questionnaires we determined expectations concerning SDD (effectiveness) experience with SOD (workload patient friendliness), as perceived by nurses physicians. A survey was embedded a group-randomized, controlled, cross-over multicenter study Netherlands which, during three 6-month periods, SDD, or standard used random order. At end...
OBJECTIVE Manual surveillance of healthcare-associated infections is cumbersome and vulnerable to subjective interpretation. Automated systems are under development improve efficiency reliability surveillance, for example by selecting high-risk patients requiring manual chart review. In this study, we aimed validate a previously developed multivariable prediction modeling approach detecting drain-related meningitis (DRM) in neurosurgical assess its merits compared conventional methods...
Young patients with aneurysmal subarachnoid hemorrhage (aSAH) and a history of migraine may have an increased risk delayed cerebral ischemia. We investigated this potential association in prospective cohort aSAH under 50 years age.In our study, we included age from 3 hospitals the Netherlands. assessed lifetime short screener. Delayed ischemia was defined as neurological deterioration lasting >1 hour not attributable to other causes by diagnostic workup. Adjustments were made for possible...
Delayed cerebral ischemia (DCI) is a major contributor to the high morbidity in patients with aneurysmal subarachnoid hemorrhage (aSAH). Spreading depolarizations may play role DCI pathophysiology. Because migraine are probably more susceptible spreading depolarizations, we investigated whether at increased risk for DCI.We included from 3 hospitals Netherlands. We assessed lifetime history short screener. was defined as neurological deterioration lasting >1 hour not attributable other causes...
In data collected during the Third International Study on Mechanical Ventilation, we compared from Netherlands with a global cohort. We hypothesized that tidal volumes (Vt) were smaller and applied positive end-expiratory pressure (PEEP) was higher in Netherlands, also use of non-invasive ventilation (NIV) outcomes both cohorts.
Introduction . Electrical cardioversion (ECV) is a short but painful procedure for treating cardiac dysrhythmias. There wide variation regarding the medication strategy to facilitate this procedure. Many different sedative techniques ECV are described. Currently, optimal prevent pain in has yet be established. The role additional analgesic agents during remains controversial, and evidence limited. Methods We conducted prospective multicenter study determine incidence of recall with propofol...