Aethele Khunda

ORCID: 0000-0003-4574-9675
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About
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Research Areas
  • Pelvic floor disorders treatments
  • Anorectal Disease Treatments and Outcomes
  • Urinary Bladder and Prostate Research
  • Urinary Tract Infections Management
  • Uterine Myomas and Treatments
  • Pelvic and Acetabular Injuries
  • Maternal and Perinatal Health Interventions
  • Enhanced Recovery After Surgery
  • Gynecological conditions and treatments
  • Ureteral procedures and complications
  • Maternal and fetal healthcare
  • Hip and Femur Fractures
  • Bone fractures and treatments
  • Sexual function and dysfunction studies
  • Cardiac Arrest and Resuscitation
  • Endometrial and Cervical Cancer Treatments
  • Endometriosis Research and Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Female Genital Mutilation/Cutting Issues
  • Urological Disorders and Treatments
  • Nerve Injury and Rehabilitation
  • Hernia repair and management
  • Trauma and Emergency Care Studies
  • Gestational Trophoblastic Disease Studies
  • Shoulder and Clavicle Injuries

South Tees Hospitals NHS Foundation Trust
2015-2025

James Cook University Hospital
2007-2023

South Tyneside and Sunderland NHS Foundation Trust
2019

University of Sunderland
2019

University of Oxford
2019

Bradford Teaching Hospitals NHS Foundation Trust
2019

Diakonissenkrankenhaus
2019

Hunter Medical Research Institute
2018

Royal Bolton Hospital
2013-2018

University Hospital Lewisham
2018

BackgroundRisk factors for maternal infection are clearly recognised, including caesarean section and operative vaginal birth. Antibiotic prophylaxis at is widely recommended because there clear systematic review evidence that it reduces incidence of infection. Current WHO guidelines do not recommend routine antibiotic women undergoing birth insufficient effectiveness. We aimed to investigate whether prevented after birth.MethodsIn a blinded, randomised controlled trial done 27 UK obstetric...

10.1016/s0140-6736(19)30773-1 article EN cc-by The Lancet 2019-05-13

To assess perinatal outcomes for pregnancies affected by suspected or confirmed SARS-CoV-2 infection.Prospective, web-based registry. Pregnant women were invited to participate if they had infection between 1st January 2020 and 31st March 2021 the impact of on maternal including miscarriage, stillbirth, fetal growth restriction, pre-term birth transmission infant.Between April 2021, study recruited 8239 participants who SARs-CoV-2 episodes in pregnancy 2021. Maternal death 14/8197 (0.2%)...

10.1016/j.ejogrb.2022.07.010 article EN cc-by European Journal of Obstetrics & Gynecology and Reproductive Biology 2022-07-19

Two patients of early adolescence age presented with medically resistant primary dysmenorrhoea. Imaging (MRI scan) confirmed an asymmetric uterine septum a unilaterally obstructed horn haematometra. Laparotomy and Tompkins metroplasty was performed to unify the cavity in each case, technique not used for this condition before. Dysmenorrhoea resolved postoperatively. One patient got pregnant spontaneously 3.5 years later delivered by emergency caesarean section at 36 weeks gestation. There...

10.1136/bcr-2024-261699 article EN BMJ Case Reports 2025-01-01

Prolapse affects 30-40% of women. Those using a pessary for prolapse usually receive care as an outpatient. This trial determined effectiveness and cost-effectiveness self-management (SM) vs clinic-based (CBC) in relation to condition-specific quality life (QoL).Parallel-group, superiority randomised controlled trial, recruiting from 16 May 2018 7 February 2020, with follow-up 17 September 2021. Women attending clinics, ≥18 years, (except Shelf, Gellhorn or Cube), retained ≥2 weeks were...

10.1016/j.eclinm.2023.102326 article EN cc-by EClinicalMedicine 2023-11-23

Pelvic organ prolapse (POP) is a common condition in women, where the downward descent of pelvic organs into vagina causes symptoms which impacts quality life. Vaginal pessaries offer an effective alternative to surgery for management POP. However, need regular follow-up can be burdensome women and requires significant healthcare resources. The TOPSY study randomised controlled trial aims determine clinical cost-effectiveness self-management vaginal pessaries. This paper describes...

10.1186/s13063-022-06681-3 article EN cc-by Trials 2022-09-05

Abstract Background Pelvic organ prolapse (or prolapse) is a common condition in women where the pelvic organs (bladder, bowel or womb) descend into vagina and cause distressing symptoms that adversely affect quality of life. Many will use vaginal pessary to treat their symptoms. Clinic-based care usually consists having fitted primary secondary setting, returning approximately every 6 months for healthcare professional review change. However, it possible could remove, clean re-insert...

10.1186/s13063-020-04738-9 article EN cc-by Trials 2020-10-08

Ectopic pregnancy is a one of the primary causes maternal mortality in first trimester. The most common site ectopic fallopian tube. Surgical management tubal includes salpingotomy or salpingectomy. Persistent can happen after due to incomplete removal tissue. However, it very rare In our case, patient had right-sided salpingectomy and histology confirmed pregnancy. She presented 19 days' later with abdominal pain, haemoperitoneum persistent high beta-HCG (B-HCG). A second laparoscopy was...

10.1136/bcr-2023-257693 article EN BMJ Case Reports 2024-01-01

Background Sepsis is a leading cause of direct and indirect maternal death in both the UK globally. All forms operative delivery are associated with an increased risk sepsis, National Institute for Health Care Excellence’s guidance recommends use prophylactic antibiotics at all caesarean deliveries, based on substantial randomised controlled trial evidence clinical effectiveness. A Cochrane review, updated 2017 (Liabsuetrakul T, Choobun Peeyananjarassri K, Islam QM. Antibiotic prophylaxis...

10.3310/hta23540 article EN publisher-specific-oa Health Technology Assessment 2019-10-01

The proximal humerus internal locking system is an fixation device consisting of a low-profile plate and screws, which used for the three- four-part fractures humerus. We describe case in screws cut out humeral head causing injury to axillary artery necessitating urgent removal implant.

10.1302/0301-620x.89b11.19264 article EN Journal of Bone and Joint Surgery - British Volume 2007-11-01

HIV epidemicity in context of STI declines: a telling discordance Decosas and Padian report, but do not discuss, noteworthy disassociation epidemic trajectory between human immunodeficiency virus (HIV) sexually transmitted infections (STI) Zimbabwe. 1 They cite estimates that, 1990 1999, prevalence increased linearly from 9% to 25%, while syndrome reports declined substantially, 963 436 cases 727 788.The authors only believe that observed declines are real, increases reported condom use by...

10.1136/sti.78.6.468 article EN Sexually Transmitted Infections 2002-12-01

"Vaginal evisceration: a report of two cases." Journal Obstetrics and Gynaecology, 22(5), pp. 568–569

10.1080/014436102760298971 article EN Journal of Obstetrics and Gynaecology 2002-01-01

Abstract Background Process evaluations have become a valued component, alongside clinical trials, of the wider evaluation complex health interventions. They support understanding implementation, and fidelity, related to intervention provide valuable insights into what is effective in practical setting by examining context which interventions are implemented. The TOPSY study consists large multi-centre randomised controlled trial comparing effectiveness pessary self-management with...

10.1186/s13063-020-04729-w article EN cc-by Trials 2020-10-08

Objectives Pelvic organ prolapse is the descent of one or more reproductive organs from their normal position, causing associated negative symptoms. One conservative treatment option pessary management. The aim this study was to investigate cost-effectiveness self-management (SM) when compared clinic-based care (CBC). A decision-analytic model developed extend economic evaluation. Methods randomised controlled trial with health SM group received: 30-minute teaching session; information...

10.1016/j.jval.2024.03.004 article EN cc-by Value in Health 2024-03-14
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