A5101483585- Geomechanics and Mining Engineering
- Civil and Geotechnical Engineering Research
- Simulation and Modeling Applications
- Advanced Sensor and Control Systems
- Advanced Algorithms and Applications
- Power Systems and Technologies
- Industrial Technology and Control Systems
- Water Quality Monitoring and Analysis
- Geoscience and Mining Technology
- Environmental and Agricultural Sciences
- Regional Economic and Spatial Analysis
- Evaluation Methods in Various Fields
- Forest, Soil, and Plant Ecology in China
- High-Voltage Power Transmission Systems
- Wireless Sensor Networks and IoT
- Multilevel Inverters and Converters
- Digital Media and Visual Art
- Radiomics and Machine Learning in Medical Imaging
- Neurological Disease Mechanisms and Treatments
- Remote Sensing and Land Use
- Embedded Systems and FPGA Design
- Silicon Carbide Semiconductor Technologies
- Adsorption and biosorption for pollutant removal
- Advanced DC-DC Converters
- Synthesis and Biological Evaluation
Hubei University of Science and Technology
2010-2024
Jinan University
2024
ShenZhen People’s Hospital
2021-2024
Anhui University
2022-2024
Southern University of Science and Technology
2024
Shanghai Ocean University
2022-2023
Sichuan Agricultural University
2022-2023
Daping Hospital
2022-2023
Army Medical University
2022-2023
Fujian Medical University
2019-2022
Tuberculosis (TB), which affects primarily the lungs (pulmonary TB) apart from other vital organs, is a life‐threatening chronic deadliest infectious disease caused by members of Mycobacterium tuberculosis (MTB) complex and mainly MTB itself. The emergence new virulent forms that are resistant to some or all first‐line second‐line anti‐TB agents, including multidrug‐resistant (MDR), extensively drug‐resistant, totally drug‐resistant strains has further aggravated spread this was increased up...
Osteoarthritis is a chronic degenerative disease based on the degeneration and loss of articular cartilage. Inflammation aging play an important role in destruction extracellular matrix, which microRNA (miRNA) key point, such as miRNA-34a-5p. Upregulation miRNA-34a-5p was previously reported rat OA model, its inhibition significantly suppressed interleukin (IL)-1β-induced apoptosis chondrocytes. However, Oxidative stress caused by reactive oxygen species (ROS) can exacerbate progression...
Abstract A series of gatifloxacin‐1,2,3‐triazole‐isatin hybrids 8a–l were designed, synthesized, and screened for their in vitro antimycobacterial activity as well cytotoxicity toward Chinese Hamster Ovary (CHO) cells. The synthesized showed considerable against MTB H 37 Rv two MDR‐MTB strains with minimal inhibitory concentration (MIC) 0.25–8 μg/ml, the hybrid 8a (MIC H37Rv : 0.25 μg/ml MIC 0.5 1 μg/ml) was found to be most active tested strains, which not inferior parent gatifloxacin (MIC:...
A series of novel 1 H ‐1,2,3‐triazole‐tethered isatin–coumarin hybrids 7a – l integrate three anti‐tuberculosis bioactive substances/pharmacophoric units including coumarin, isatin, and I ‐ A09 were designed, synthesized, tested for their in vitro anti‐mycobacterial activity against Mycobacterium smegmatis tuberculosis H37Rv as well cytotoxicity VERO cell line. The results showed that all exhibited weak to moderate the two strains with minimum inhibitory concentration ranging from 50 200 μg/mL.
With the development of high-performance wide-band-gap devices and increasing converter frequency, planar transformers are widely used in high-frequency high-power-density power conversions. Due to skin effect proximity effect, accurate thermal analysis a simplified model needed for quick verification as well system design. This paper proposes two simplification models based on transformer’s impedance network. The internal loss coupling between each component first analyzed. Then, radiation...
Herein, a combined multipoint picking scheme was proposed, and the sizes of end bud picker were selectively designed. Firstly, abstracted as fixed-size box, it assumed that tea buds in box have certain probability being picked. Then, coverage greedy algorithm designed to make few numbers set possible cover all reduce picking. Furthermore, Graham minimum bounding applied fine-tune footholds each optimal set, so concentrated middle boxes much possible. Moreover, geometric center taken point,...
Abstract In this work, a series of butylene tethered heteronuclear 7‐fluoroisatin‐isatin scaffolds 4a to 4h were designed and synthesized, the antimycobacterial activity profiles, cytotoxicity together with inhibitory against MTB DNA gyrase, also investigated. All synthesized active H 37 Rv MDR‐MTB strains, some them more potent than isoniazid ( INH ), rifampicin RIF ethambutol EMB ) strain. The structure‐activity relationship demonstrated that substituents on C‐3 position 7‐fluoroisatin...
The balance between cell quiescence and proliferation is fundamental to tissue physiology homeostasis. Recent studies have shown that not a passive homogeneous state but actively maintained heterogeneous. These cellular characteristics associated with were observed primarily in cultured cells under static medium. However, vivo face different microenvironmental conditions, particularly, interstitial fluid flows distributed through extracellular matrices. Interstitial flow exerts shear stress...