A5027598185- Animal Virus Infections Studies
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Intraocular Surgery and Lenses
- Acute Ischemic Stroke Management
- Musculoskeletal pain and rehabilitation
- Blood groups and transfusion
- Gastric Cancer Management and Outcomes
- Medical Imaging Techniques and Applications
- Neuroendocrine Tumor Research Advances
- Reproductive tract infections research
- RNA Interference and Gene Delivery
- Liver Disease Diagnosis and Treatment
- Corneal surgery and disorders
- Animal Disease Management and Epidemiology
- Intraoperative Neuromonitoring and Anesthetic Effects
- Hernia repair and management
- Thermal Regulation in Medicine
- Cytokine Signaling Pathways and Interactions
- Electroconvulsive Therapy Studies
- Neurosurgical Procedures and Complications
- Management of metastatic bone disease
- Histone Deacetylase Inhibitors Research
Harbin Medical University
2025
Peking University
2020-2025
Peking University Third Hospital
2020-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2025
Research Management (Norway)
2025
Southwest University
2025
Fujian Medical University
2013-2023
Mengchao Hepatobiliary Hospital
2022
Union Hospital
2019
Jilin University
2008-2019
Abstract Glucagon‐like peptide‐1 (GLP‐1), derived from enteroendocrine cells, is a pivotal hormone crucial for blood glucose regulation. Menin, encoded by the MEN1 gene and known its tumor suppressor role, abundantly expressed in intestine. Previous research has demonstrated that acute Men1 excision reverses preexisting intolerance high‐fat diet‐fed mice. However, impact on GLP‐1 expression cells not been investigated. In present study, both knockdown of administration MI‐463 menin inhibitor...
Bovine neosporosis, a protozoal disease caused by Neospora caninum ( N. caninum), poses significant threat to the global cattle industry, resulting in substantial economic losses that are difficult quantify. The current lack of effective commercial vaccines and specific treatments highlights urgent need for development potent drugs against caninum. In this study, we investigate efficacy aurintricarboxylic acid (ATA), derivative polyaromatic carboxylic acid, both vitro vivo. Cell cytotoxicity...
The poor bioavailability of curcumin and its derivatives limits their antitumor efficacy clinical translation. Although derivative C210 has more potent activity than curcumin, it a similar deficiency to curcumin. In order improve accordingly enhance in vivo, we developed redox-responsive lipidic prodrug nano-delivery system C210. Briefly, synthesized three conjugates oleyl alcohol (OA) via different linkages containing single sulfur/disulfide/carbon bonds prepared nanoparticles using...
Background. The incidence of nonfunctional pancreatic neuroendocrine neoplasms (NF-pNENs) has been increasing annually. This study is aimed at investigating the clinicopathological characteristics and high-risk factors NF-pNENs influence surgical treatment on prognosis NF-pNEN patients with liver metastases. Methods. pNEN in this were obtained from Surveillance, Epidemiology, End Results (SEER) database. analyzed diagnosed 2000 to 2017 who met inclusion criteria. A retrospective analysis was...
Stress urinary incontinence (SUI) is common, impacts women's quality of life and generates high costs. Physiotherapy the first line therapy if it fails, suburethral slings are currently gold standard in SUI surgery. Bulking agents injected periurethrally might be a beneficial alternative, but there paucity data on bulking therapy. Aim current-study was to analyze efficacy safety setting tertiary referral center prospectively.In last 13 years 514 elderly women with were treated by injection...
Rehabilitation is an essential part of achieving health for all, whereas the estimates rehabilitation needs, especially elderly individuals in China, are not clear.Compared with 1990, prevalence and years life lived disability conditions need China increased by 71.3% 77.0% 2019, respectively, at a rate much higher than global average.This study mainly presents scientific data systematic analysis current state challenges needs (aged 60 above) based on World Health Organization Need Estimator.
Objective: To study the safety and efficacy of transjugular intrahepatic portosystemic shunt (TIPS) combined with iodine-125 (125Ⅰ) seed strands implantation in patients hepatocellular carcinoma portal vein tumor thrombosis. Methods: 25 cases diffuse thrombus type Ⅲ/Ⅳ requiring TIPS were simultaneously implanted 125Ⅰseed strand. Tumor was controlled 125I brachytherapy to keep pathway unobstructed, reduce pressure, observe changes cause death patients. During same period, 30 without strand...
Objective To evaluate the role of 16α-[18F]fluoro-17β-oestradiol(18F-FES)PET/CT in diagnosis and management breast cancer.Methods Nineteen pre-operation cases with cancer 7 post-operation metastatic underwent 18F-FES PET/CT 18F-FDG PET/CT,and comparative analysis expression estrogen receptor (ER)was performed.Results Of primary lesions,the ER was positive 9 patients (10 lesions),negative 10 (11 lesions).The maximum standardized uptake value (SUVmax) for FES positively related to lesion size...