- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Metal and Thin Film Mechanics
- Diamond and Carbon-based Materials Research
- Pelvic and Acetabular Injuries
- Spine and Intervertebral Disc Pathology
- Boron and Carbon Nanomaterials Research
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Elbow and Forearm Trauma Treatment
- Shoulder Injury and Treatment
- Advanced materials and composites
- Postharvest Quality and Shelf Life Management
- Osteoarthritis Treatment and Mechanisms
- Polymer Surface Interaction Studies
- Total Knee Arthroplasty Outcomes
- Intraoperative Neuromonitoring and Anesthetic Effects
- Growth Hormone and Insulin-like Growth Factors
- Polysaccharides and Plant Cell Walls
- Concrete and Cement Materials Research
- Spondyloarthritis Studies and Treatments
- Dermatologic Treatments and Research
- Spinal Dysraphism and Malformations
Columbia University
2017-2024
General Hospital of Guangzhou Military Command
2023
Northeast Forestry University
2012-2021
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2017-2021
Wenzhou Medical University
2017-2021
Nanjing Drum Tower Hospital
2007-2017
Zhejiang Sci-Tech University
2012-2016
Southeast University
2016
Jilin University
2016
Nanjing University
2010
ABSTRACT Developing effective treatment for osteoarthritis (OA), a prevalent and disabling disease, has remained challenge, primarily because of limited understanding its pathogenesis late diagnosis. In the subchondral bone, rapid bone loss after traumatic injuries sclerosis at advanced stage OA are well-recognized hallmarks disease. Recent studies have further demonstrated crucial contribution in development OA. However, microstructural basis these changes not been examined thoroughly,...
In Brief Study Design. A prospective study was designed to investigate the circulating leptin level in girls with adolescent idiopathic scoliosis (AIS). Objective. To determine levels AIS girls, and its associations body mass bone mass. Summary of Background Data. Abnormal growth pattern osteopenia have been well documented patients throughout peripubertal period. Leptin has shown regulate whole particularly during childhood adolescence. However, leptin, relationships between lower mass,...
In order to improve the low-temperature cracking resistance and durability of high-modulus asphalt mixture, this article proposes use Trinidad Lake Asphalt (TLA) polyester fibre complex methods obtain based on indoor accelerated load, low bending temperature, freeze-thaw splitting APA fatigue test study influence TLA content permanent deformation performance, water stability, crack mixtures. Meanwhile, it reveals mechanism composite modified mixture recommends best solution is 30% + 3‰ fibre.
Knee osteoarthritis (OA), characterized by multiple joint tissue degenerations, remains a significant clinical challenge. Recent evidence suggests that crosstalk within the osteochondral unit may drive OA progression. Although structural-biomechanical properties of bone and cartilage have been studied, potential interaction in context has yet to be investigated. We performed comprehensive structural biomechanical quantification cartilage, subchondral plate (SBP), trabecular (STB) using 101...
Previous studies have shown a significant association between osteopenia and adolescent idiopathic scoliosis (AIS). And initial bone mineral density (BMD) was proposed to serve as new prognostic factor of curve progression in AIS. However, it remains unknown whether there is link the status outcome brace treatment. This study aimed investigate could influence final treatment AIS.Girls with AIS treated were recruited. These patients either completed treatment, or indicated for correction...
Halo-femoral traction could gradually improve the coronal and sagittal deformity restore trunk balance through elongation of spine. The purpose this retrospective study was to assess effectiveness after anterior spinal release in management severe idiopathic congenital scoliosis. Sixty patients with rigid curve treated release, traction, second stage posterior fusion were recruited for study. Idiopathic Scoliosis (IS) group 30 (23 females 7 males) mean age 15.5 years. average Cobb angle...
Abstract Adolescent idiopathic scoliosis is a complex disease with unclear etiopathogenesis. Systemic and persistent low bone mineral density an independent prognostic factor for curve progression. The fundamental question of how quality affected in AIS remains controversy because there lack site-matched control detailed analysis on bone-related parameters. In this case-control study, trabecular biopsies from iliac crest were collected intra-operatively 28 severe patients 10 matched controls...
To date, no study had reported the phenomenon of deteriorated postoperative cervical tilt in Lenke type 2 adolescent idiopathic scoliosis patients. The purpose this is to evaluate patients with right-elevated shoulder treated by either full fusion or partial/non proximal thoracic curve. A total 30 AIS preoperative underwent posterior spinal instrumentation from 2009 2011 were included study. All subjects divided into groups according selection upper instrumented vertebra. There 14 cases...
In Brief Study Design. A retrospective study was performed through measurements on MRI images in adolescent idiopathic scoliosis (AIS) patients and age-matched adolescents. Objectives. To investigate the position of cerebellar tonsil AIS with a Cobb angle >40° comparison healthy adolescents to determine relationships age, sex, curve severity, patterns. Summary Background Data. There have been increasing evidences implying that may present subtle or subclinical neurologic dysfunction higher...
Objective: To evaluate the effectiveness and to identify predictive factors of standardized brace treatment for girls with adolescent idiopathic scoliosis (AIS). Methods: From July 2003 2009, 142 AIS completed treatment. These patients had a mean age (13.1 ± 1.5) years (range, 10.1–15.9 years), main curve 29.6°± 5.4° 20°–40°), Risser grade 2.0 1.5 0–4) before Based on whether their progressed or not, were divided into two groups: (Group Pr, n = 27, 19%) non-progressed NP, 115, 81%), then...
In Brief Study Design. A prospective longitudinal follow-up study. Objectives. To assess the effect of standardized bracing treatment on bone mineral density (BMD) accumulation in girls with adolescent idiopathic scoliosis (AIS) and to analyze possible influencing factors BMD during treatment. Summary Background Data. The association between osteopenia AIS has been reported numerous studies. Although a very recent study argued that did not appear affect accumulation, impact initial status...
Viscoelasticity of the periodontal ligament (PDL) plays an important role in load transmission between tooth and alveolar bone, as well movement. This paper provides a novel nanoindentation experiment combination with rheological model to characterize viscoelastic mechanical properties PDL. Two creep models indentation experiments Berkovich spherical indenter based on Zener were developed. The hardness reduced modulus determined by using indenter. parameters identified through curve...