A5085109041- Scoliosis diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Connective tissue disorders research
- Spinal Fractures and Fixation Techniques
- Bone health and osteoporosis research
- Medical Imaging and Analysis
- TGF-β signaling in diseases
- Pelvic and Acetabular Injuries
- Effects of Vibration on Health
- Vitamin D Research Studies
- Stroke Rehabilitation and Recovery
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Vasculitis and related conditions
- Antimicrobial Peptides and Activities
- Oral and Craniofacial Lesions
- Craniofacial Disorders and Treatments
- Immune cells in cancer
- Osteoarthritis Treatment and Mechanisms
- Hip disorders and treatments
- Geology and Paleoclimatology Research
- Musculoskeletal pain and rehabilitation
- Geological formations and processes
- Extracellular vesicles in disease
- Coastal wetland ecosystem dynamics
- Spaceflight effects on biology
China University of Geosciences
2025
Chinese University of Hong Kong
2016-2024
Hainan Medical University
2018-2024
Central South University
2024
Weatherford College
2023
Prince of Wales Hospital
2017
Nanjing University
2016
Wetlands, as crucial terrestrial carbon reservoirs, have recently suffered severe degradation due to intense human activities. Lacustrine sediments serve vital indicators for understanding wetland environmental changes. In the current paper, porewater samples were extracted from lacustrine sediment in three boreholes with a depth of ~75 cm Huixian karst wetland, southwest China, study chemical and dissolved inorganic (DIC) evolution under anthropogenic influence. Two are situated beneath...
The manipulation of macrophage recruitment and their shift in the M1/M2 ratio is a promising approach to mitigate osteoarthritis (OA). Nevertheless, current clinical medication available for OA only palliative may result undesirable outcomes. Hence, it urgent explore alternative disease-modifying drug supplement that are both safer more effective treatment, like probiotic probiotic-derived membrane vesicles.The synovial inflammation cartilage damage collagenase-induced (CIOA) mice were...
ABSTRACT Recently, noncoding RNAs have been thought to play important roles in the sporadic occurrence of spinal deformity adolescent idiopathic scoliosis (AIS). As a prognostic factor for curve progression, low bone mass has hypothesized crosstalk with AIS pathogenesis. Abnormal osteoblasts activities are reported without clear mechanism. In this study, biopsies from patients and control subjects primary derived those samples were used identify potential microRNA (miRNA) candidates that...
Adolescent idiopathic scoliosis (AIS) is a prevalent spinal deformity occurring during peripubertal growth period that affects 1‐4% of adolescents globally without clear etiopathogenetic mechanism. Low bone mineral density an independent and significant prognostic factor for curve progression. Currently, the cause underlying low mass in AIS remains elusive. Osteocytes play important role metabolism homeostasis, but its has not been studied. In present study, iliac tissues were harvested from...
Abstract Adolescent idiopathic scoliosis is a complex disease with unclear etiopathogenesis. Systemic and persistent low bone mineral density an independent prognostic factor for curve progression. The fundamental question of how quality affected in AIS remains controversy because there lack site-matched control detailed analysis on bone-related parameters. In this case-control study, trabecular biopsies from iliac crest were collected intra-operatively 28 severe patients 10 matched controls...
Abstract Congenital muscular torticollis (CMT) is a common musculoskeletal abnormality in children, which has been characterized by unclarified pathological changes the sternocleidomastoid muscle (SCM) and various hypothetical etiologies. There are 2 main etiologies for CMT literature: 1 infers that may represent sequela of an intrauterine or perinatal compartment syndrome, other regard as maldevelopment fetal SCM. To better understand etiopathogenesis CMT, we screened necks 1-day-old...
Abstract Bone densitometry revealed low bone mass in patients with adolescent idiopathic scoliosis (AIS) and its prognostic potential to predict curve progression. Recent studies showed differential circulating miRNAs AIS but their diagnostic links have not been well-documented. The present study aimed compare miRNA profiles tissues collected from non-scoliotic subjects, explore if the selected candidates could be useful biomarkers for AIS. Microarray analysis identified miR-96-5p being most...
There are limited data on the in vivo natural kinematics of lumbar spinous process. This paper intends to explore effect lifting load movement mode process and its biomechanical changes.Ten asymptomatic subjects between ages 25 39 underwent CT scans spine supine position, 3D models L3-L5 were constructed. Using a Dual Fluoroscopy Imaging System (DFIS), instantaneous orthogonal fluoroscopic images each subject's flexion-extension, left-right bending, rotational movements taken under different...
Administering anti-osteoporotic agents to patients perioperatively is a widely accepted approach for improving bone fusion rates and reducing the risk of complications. The best spinal surgery remain unclear.
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that associated with low bone mineral density (BMD). Vitamin D (Vit-D) supplementation has been suggested to improve BMD in AIS, and its outcomes may be related genetic factors. The present study aimed (a) investigate the synergistic effect between BMD-related gene (wingless-related integration site 16,
<title>Abstract</title> <bold>Purpose:</bold> There are limited data on the natural kinematics of lumbar pedicle in vivo. This study investigated range motion screw insertion point when normal subjects moved under physiological loads. <bold>Methods:</bold> Ten healthy volunteers aged 25 to 39 years were recruited. A combination a dual fluoroscopic imaging system (DFIS) and CT technology was used. With computer assistance, three-dimensional reconstructed model each segment spine created by...
OBJECTIVE To explore the dynamic changes of lumbosacral sagittal parameters after real-time three-dimensional navigation assisted minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) and traditional open TLIF for treatment degenerative disease. METHODS The clinical data 61 patients with disease underwent single-segment surgery from September 2017 to 2019 were retrospectively analyzed. Among them, 31 cases MIS-TLIF 3D techniques (MIS-TLIF group) another 30 conventional...
Previous studies have reported abnormal muscle morphology and functions in patients with adolescent idiopathic scoliosis (AIS). To answer whether such abnormalities could be reflected their circulation clinical implication for predicting curve progression to the surgical threshold, this preliminary study explored presence of baseline muscle-related proteins association progression. Plasma samples were collected at first visit AIS, divided into non-progressive or progressive groups (N = four...
Abstract Background To compare the accuracy and deviation direction of pedicle screw placement in apical region patients with Lenke type 1 adolescent idiopathic scoliosis (AIS) under navigation using calibration techniques, to analyze related factors affecting clinical significance techniques. Methods This was a retrospective analysis 43 who were diagnosed AIS our hospital from October 2017 2020 underwent posterior correction internal fixation assistance. According whether technology used...