A5100319571- Scoliosis diagnosis and treatment
- Cardiac Valve Diseases and Treatments
- Connective tissue disorders research
- Bone health and osteoporosis research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Traumatic Brain Injury and Neurovascular Disturbances
- Bladder and Urothelial Cancer Treatments
- Nutrition and Health in Aging
- TGF-β signaling in diseases
- Hip disorders and treatments
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Lymphatic System and Diseases
- Atrial Fibrillation Management and Outcomes
- Effects of Vibration on Health
- Aquaculture disease management and microbiota
- Urinary and Genital Oncology Studies
- Infective Endocarditis Diagnosis and Management
- Medical Imaging Techniques and Applications
- Congenital Heart Disease Studies
- Enhanced Recovery After Surgery
- Sirtuins and Resveratrol in Medicine
- Nausea and vomiting management
Affiliated Hospital of Taishan Medical University
2012-2025
Shandong First Medical University
2023-2025
Chinese University of Hong Kong
2016-2024
University of Hong Kong
2024
Qilu Hospital of Shandong University
2023-2024
Anglia Ruskin University
2024
Qingdao University
2024
Qingdao Municipal Hospital
2024
Wuhan University
2024
Renmin Hospital of Wuhan University
2024
Elevated intracranial pressure (ICP), a common complication in traumatic brain injuries (TBI), can lead to optic nerve sheath diameter (ONSD) enlargement and flow spectrum changes from the internal carotid artery (ICA) middle cerebral (MCA). This study will investigate use of Cervical-Cerebral Arterial Ultrasound (CCAU) for non-invasive ICP assessment evaluating related indices' clinical utility TBI patients with decompressive craniotomy (DC). ONSD were measured within 24 h after DC 106 via...
Objective This study aims to develop and validate a nomogram that combines traditional ultrasound radiomics features with clinical parameters assess early intracranial hypertension (IH) following primary decompressive craniectomy (DC) in patients severe traumatic brain injury (TBI). The incorporates the Shapley Additive Explanations (SHAP) method interpret model. Methods included 199 TBI (training cohort: n = 159; testing 40). Postoperative images of optic nerve sheath (ONS) were obtained at...
ABSTRACT Recently, noncoding RNAs have been thought to play important roles in the sporadic occurrence of spinal deformity adolescent idiopathic scoliosis (AIS). As a prognostic factor for curve progression, low bone mass has hypothesized crosstalk with AIS pathogenesis. Abnormal osteoblasts activities are reported without clear mechanism. In this study, biopsies from patients and control subjects primary derived those samples were used identify potential microRNA (miRNA) candidates that...
Exercise in later life is important for bone health and delays the progression of osteoporotic loss. Osteocytes are major cells responsible transforming mechanical stimuli into cellular signals through their highly specialized lacunocanalicular networks (LCN). Osteocyte activity LCN degenerate with aging, thus might impair effectiveness exercise on health; however, underlying mechanism clinical implications remain elusive. Herein, we showed that deletion Sirt3 osteocytes could formation...
Adolescent idiopathic scoliosis (AIS) is a prevalent spinal deformity occurring during peripubertal growth period that affects 1‐4% of adolescents globally without clear etiopathogenetic mechanism. Low bone mineral density an independent and significant prognostic factor for curve progression. Currently, the cause underlying low mass in AIS remains elusive. Osteocytes play important role metabolism homeostasis, but its has not been studied. In present study, iliac tissues were harvested from...
Abstract Adolescent idiopathic scoliosis is a complex disease with unclear etiopathogenesis. Systemic and persistent low bone mineral density an independent prognostic factor for curve progression. The fundamental question of how quality affected in AIS remains controversy because there lack site-matched control detailed analysis on bone-related parameters. In this case-control study, trabecular biopsies from iliac crest were collected intra-operatively 28 severe patients 10 matched controls...
To compare four risk scores with regard to their validity predict in-hospital mortality after heart valve surgery in a multicenter patient population of China.From January 2009 December 2012, data from 12,412 consecutive patients older than 16 years who underwent at cardiac surgical centers were collected and scored according the EuroSCORE II, Ambler score, NYC STS score. The divided into two subgroups types procedures, performance for each group was assessed. Calibration assessed by...
Dual antiplatelet therapy (DAPT) improves early post-operative graft patency, but the optimal DAPT strategy for patients after coronary artery bypass grafting (CABG) has not been confirmed. We sought to evaluate effect of aspirin plus ticagrelor versus clopidogrel on saphenous vein (SVG) patency within 1 year CABG.Between October 2017 and December 2018, 147 consecutive undergoing elective CABG at Changhai Hospital were randomized into two groups: group AT, receiving 100 mg/d 2×90 mg/d; AC,...
Effective antiplatelet therapy is critical for patients with ST-segment elevation myocardial infarction (STEMI) and receiving primary percutaneous coronary interventions (PPCI). Intracoronary (IC) intravenous (IV) administration of tirofiban are commonly used during the procedure PPCI. However, which better route have not been fully evaluated.A comprehensive literature search RCTs that comparing IC IV in STEMI undergoing PPCI was conducted, were published as May 7, 2022, PubMed, Embase,...
The chemiluminescent microparticle immunoassay (CMIA) is widely used for the quantitative determination of B-type natriuretic peptide (BNP) in human ethylenediaminetetraacetic acid plasma. Rheumatoid factor (RF) usually thought to result a positive interference immunoassays, but it not clear whether its presence plasma can lead interferences CMIA BNP.The estimation BNP recovery was carried out by diluting high-concentration samples with RF-positive or RF-negative at ratio 1:9. diluted were...
Abstract Bone densitometry revealed low bone mass in patients with adolescent idiopathic scoliosis (AIS) and its prognostic potential to predict curve progression. Recent studies showed differential circulating miRNAs AIS but their diagnostic links have not been well-documented. The present study aimed compare miRNA profiles tissues collected from non-scoliotic subjects, explore if the selected candidates could be useful biomarkers for AIS. Microarray analysis identified miR-96-5p being most...
Abstract Background Whether distributions and prognostic values of high-sensitivity cardiac troponin (hs-cTn) T I are different across normoglycemic, prediabetic, diabetic populations is unknown. Methods 10127 adult participants from the National Health Nutrition Examination Survey 1999–2004 with determined glycemic status measurement at least one hs-cTn assays were included, whom healthy presumably prediabetic selected to investigate pure impacts on hs-cTn. The nonparametric method...
The predictive value of growth differentiation factor-15 (GDF-15) in coronary microvascular dysfunction (CMD) following primary percutaneous intervention (PPCI) ST-segment elevation myocardial infarction (STEMI) patients is unclear.
Residual kidney function (RKF) is an important prognostic indicator in peritoneal dialysis (PD) patients. So far, there are no prediction tools available for RKF, and the association between serum bicarbonate RKF has received little attention patients with PD. We aimed to develop a nomogram preservation of based on time-averaged (TA-Bic) levels.
Aims: Changes in myocardial mitochondrial morphology and function premature ventricular contractions (PVCs)-induced cardiomyopathy (PVCCM) remain poorly studied. Here, we investigated the effects of PVCs with different coupling intervals (CIs) on remodelling a canine model PVCCM. Methods Results: Twenty-one beagles underwent pacemaker implantation were randomised into sham (n = 7), short-coupled (SCP, n long-coupled (LCP, 7) groups. Right (RV) apical bigeminy was produced for 12-week to...