A5007721143- Pharmacological Effects of Natural Compounds
- Ginseng Biological Effects and Applications
- Single-cell and spatial transcriptomics
- Immune cells in cancer
- Phytochemistry and biological activity of medicinal plants
- Traditional Chinese Medicine Analysis
- Acute Myeloid Leukemia Research
- MicroRNA in disease regulation
- Cancer Mechanisms and Therapy
- Circular RNAs in diseases
- Chromatography in Natural Products
- Cancer-related molecular mechanisms research
- Lipid metabolism and disorders
Beijing University of Chinese Medicine
2022-2024
Zhejiang University
2023
Background/Aim. Rhubarb, a traditional Chinese medicine derived from three species, is commonly used in the prescriptions for promoting blood circulation and removing stasis based on its effects of dredging meridians. It has been reported that rhubarb can protect vessels by reducing inflammation inhibiting vascular endothelial injury (VEI), but effective components mechanism VEI are still unclear. This study aimed to compare differences chemical compositions species their inhibitory effect...
Abstract Background Cytotoxic T‐lymphocyte (CTL)‐mediated therapy has become the central theme of cancer immunotherapy. The present study emphasized role CTLs in acute myeloid leukemia (AML) and aimed to understand cytogenetic markers monitoring AML prognostic outcomes clinical treatment responses. Methods Seurat was employed analyze single‐cell RNA sequencing data GSE116256. CellChat used detect cell–cell interactions determine CTLs. marker genes were extracted randomForestSRC construct a...
To maintain the precision and stability of efficacy classical formulas, this study compared origins specifications Bupleuri Radix revealed precise application regularity Bupleurum chinense(Beichaihu) scorzonerifolium(Nanchaihu) in formulas. The indications formulas with as sovereign drug Treatise on Cold Damage Miscellaneous Diseases(Shang Han Za Bing Lun) were investigated. difference well differences chemical composition, liver-protecting lipid-lowering effects decoctions Beichaihu...