Xiaohui Zhou

ORCID: 0000-0002-6375-4497
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About
Contact & Profiles
Research Areas
  • Urinary Bladder and Prostate Research
  • Epigenetics and DNA Methylation
  • Alzheimer's disease research and treatments
  • Cardiac Structural Anomalies and Repair
  • Mechanical Circulatory Support Devices
  • Hormonal and reproductive studies
  • Diet and metabolism studies
  • Sexual function and dysfunction studies
  • Neurological Disorders and Treatments
  • Folate and B Vitamins Research
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • Prostate Cancer Diagnosis and Treatment
  • Genetic Syndromes and Imprinting
  • Cardiac Fibrosis and Remodeling
  • Neurological Disease Mechanisms and Treatments
  • Healthcare and Venom Research
  • Hepatitis B Virus Studies
  • Parathyroid Disorders and Treatments
  • Pelvic floor disorders treatments
  • Tea Polyphenols and Effects
  • Dementia and Cognitive Impairment Research
  • Cardiac Arrhythmias and Treatments
  • Cardiac Ischemia and Reperfusion
  • Cardiac Valve Diseases and Treatments

China Pharmaceutical University
2012-2025

Chengdu University of Technology
2018-2025

Stomatology Hospital
2021-2024

Shenzhen Luohu People's Hospital
2024

Hebei Agricultural University
2023-2024

Jiangsu Province Hospital
2017-2024

Institute of Botany
2020-2024

Zhejiang A & F University
2024

Chinese Academy of Sciences
2020-2024

Yunnan Agricultural University
2023-2024

Brain derived neurotrophic factor (BDNF) has been known to play an important role in various mental disorders or diseases such as Alzheimer's disease (AD). The aim of our study was assess whether BDNF promoter methylation peripheral blood able predict the risk AD. A total 44 AD patients and 62 age- gender-matched controls were recruited current case-control study. Using bisulphite pyrosequencing technology, we evaluated four CpG sites BDNF. Our results showed that significantly higher cases...

10.1371/journal.pone.0110773 article EN cc-by PLoS ONE 2014-11-03

ABSTRACT The Yarlung Zangbo River (YLZB), the world's highest plateau river, possesses a particularly fragile ecosystem, making it highly vulnerable to global climate change. Understanding changes in YLZB habitat quality and their driving mechanisms is crucial for ecological protection sustainable development region. Based on land use data from 2000 2020, we conducted quantitative study spatiotemporal of YLZB. This employed model, Land Use Transition Matrix, optimal parameter geographical...

10.1002/ece3.70807 article EN cc-by Ecology and Evolution 2025-01-31

We aim to improve the product quality of GABA raw Pu-erh tea during development and processing. In this study, headspace solid-phase microextraction gas chromatography-mass spectrometry technology combined with relative odor activity evaluations was used compare volatile compounds sun-dried green tea. Sensory evaluation showed a higher aroma score than that tea, significant differences in type purity. A total 147 13 categories were detected, which differed composition quantity between two...

10.3390/foods12244512 article EN cc-by Foods 2023-12-18

Kidney is an important organ for ketone body metabolism. However, the role of abnormal metabolism and its possible function in tumorigenesis clear cell renal carcinoma (ccRCC) have not yet been elucidated. Three differentially expressed key enzymes involved metabolism, ACAT1, BDH2, HMGCL, were screened out between ccRCC normal kidney tissues using GEO TCGA databases.We confirmed that transcription protein expression HMGCL significantly lower by real-time RT-PCR IHC assays. Those patients...

10.3389/fonc.2019.01422 article EN cc-by Frontiers in Oncology 2019-12-17

Aberrant DNA methylation has been observed in the patients with Alzheimer's disease (AD), a common neurodegenerative disorder elderly. OPRD1 encodes delta opioid receptor, member of family G-protein-coupled receptors. In current study, we compare levels promoter CpG sites (CpG1, CpG2, and CpG3) between 51 AD cases 63 controls using bisulfite pyrosequencing technology. Our results show that significantly higher CpG3 is found than controls. Significant associations are several biochemical...

10.1371/journal.pone.0172335 article EN cc-by PLoS ONE 2017-03-02
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