A5061281547- Pharmacological Effects of Natural Compounds
- Chromatography in Natural Products
- Traditional Chinese Medicine Analysis
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Ginseng Biological Effects and Applications
- Medicinal Plant Pharmacodynamics Research
- Food Quality and Safety Studies
- Drug Transport and Resistance Mechanisms
- Phytochemicals and Antioxidant Activities
- Phytochemistry and biological activity of medicinal plants
- Polysaccharides and Plant Cell Walls
- Metabolomics and Mass Spectrometry Studies
- Winter Sports Injuries and Performance
- Microbial Metabolites in Food Biotechnology
- Martial Arts: Techniques, Psychology, and Education
- Medicinal Plants and Neuroprotection
- Medicinal Plants and Bioactive Compounds
- Cynara cardunculus studies
- Traditional Chinese Medicine Studies
- Pomegranate: compositions and health benefits
- Bioactive Natural Diterpenoids Research
- Plant-based Medicinal Research
- Plant biochemistry and biosynthesis
- Bacteriophages and microbial interactions
Beijing University of Chinese Medicine
2016-2025
Minzu University of China
2023-2024
Henan University of Science and Technology
2023
Jiangsu University of Science and Technology
2021-2022
Rensselaer Polytechnic Institute
2019
State Administration of Traditional Chinese Medicine of the People's Republic of China
2019
Shanghai University of Traditional Chinese Medicine
2019
South Central Minzu University
2009-2017
Wuhan University
2016-2017
Wuhan Polytechnic University
2011-2016
Mulberry (Morus spp., Moraceae) is an important economic crop plant and rich in flavonoids anthocyanidins ripe fruits. Anthocyanins are glycosides of anthocyanidins. Flavanone 3-hydroxylase (F3H) catalyzes the conversion naringenin into dihydroflavonols responsible for biosynthesis flavonols In this study, MazsF3H was cloned characterized from Morus atropurpurea var. Zhongshen 1. Conserved motif analysis based on alignment phylogenetic indicated that belonged to 2-oxoglutarate-dependent...
Two new compounds, coniferyl 9-O-[beta-D-apiofuranosyl(1-->6)]-O-beta-D-glucopyranoside (1) and sinapyl 9-O-[beta-d-apiofuranosyl(1-->6)]-O-beta-D-glucopyranoside (2), were isolated from the seeds of Punica granatum (pomegranate), together with five known 3,3'-di-O-methylellagic acid (3), 3,3',4'-tri-O-methylellagic (4), phenethyl rutinoside, icariside D1, daucosterol. The structures 1 2 elucidated by spectroscopic data analysis. Compounds 1-4 exhibited antioxidant activity, which was...
Chalcones, which have characteristic 1,3-diaryl-2-propen-1-one skeleton, are mainly produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora, Glycyrrhiza, Humulus, Scutellaria, Parartocarpus, Ficus, Dorstenia, Morus, Artocarpus, so forth. They become interest the research development natural antitumor agents over past decades due to their broad range mechanisms including anti-initiation, induction apoptosis, antiproliferation, antimetastasis, antiangiogenesis,...
Abstract Background The COVID-19 pandemic has brought about significant changes in the educational landscape, with a shift towards e-learning and remote teaching practices. As such, it become increasingly important to understand role of innovative practices, sustainable learning, adoption tools leveraging academic motivation for students’ mental well-being. Purpose study aims determine whether can helpful wellbeing students directly through tools, learning considering teaching. Methods...
Menthae Haplocalycis herba, one kind of Chinese edible herbs, has been widely utilized for the clinical use in China thousands years. Over last decades, studies on chemical constituents herba have performed. However, less attention paid to non-volatile components which are also responsible its medical efficacy than volatile constituents. Therefore, a rapid and sensitive method was developed comprehensive identification using ultra-high performance liquid chromatography coupled with linear...
C-glycosides are commonly found in medicinal plants and exhibit extensive structural diversity along with various bioactivities, including antibacterial, anti-inflammatory, antiviral, antioxidant, antineoplastic activities. In C-glycosides, the anomeric carbon of sugar moiety is directly connected to an aglycone through carbon-carbon bonding. Compared O-glycosides, structurally stable resistant acids enzymes. Consequently, they typically unbreakable, resulting poor absorbability low...
Objective . To investigate the absorption property of representative hydrolyzable tannin, namely corilagin, and its hydrolysates gallic acid (GA) ellagic (EA) from Fructus Phyllanthi tannin fraction (PTF) in vitro Methods Caco-2 cells monolayer model was established. Influences PTF on viability were detected with MTT assay. The transport across monolayers examined for different time points, concentrations, secretory directions. inhibitors P-glycoprotein (P-gp), multidrug resistance proteins...
Zika virus (ZIKV) is an enveloped RNA from the flavivirus family that can cause fetal neural abnormalities in pregnant women. Previously, we established ZIKV-EP (envelope protein) binds to human placental chondroitin sulfate (CS), suggesting CS may be a potential host cell surface receptor ZIKV pathogenesis. In this study, further characterized GAG disaccharide composition of other biological tissues (i.e., mosquitoes, brain cells, and eye tissues) pathogenesis investigate role tissue...
Influenza is an acute respiratory infection disease caused by the influenza virus. At present, due to high mutation rate of virus, it difficult for existing antiviral drugs play effective effect continually, so urgent develop a new anti-influenza drug. Recently, more and studies have been conducted on activity Astragalus membranaceus , but specific mechanism this traditional Chinese medicine not clear. In study, results proved that injection showed obvious virus activity. It could improve...
Abstract Two new flavonoid‐type C ‐glycosides, trollisin I (=(1 S )‐1,5‐anhydro‐1‐[2‐(3,4‐dihydroxyphenyl)‐5‐hydroxy‐7‐methoxy‐4‐oxo‐4 H ‐[1]benzopyran‐8‐yl]‐2‐ O ‐(2‐methylbutanoyl)‐ D ‐glucitol; 1 ) and its 2‐ ‐benzoyl congener II ( 2 ), were isolated from Trollius chinensis Bunge , together with the two known compounds 2″‐ ‐(2′′′‐methylbutanoyl)isoswertisin 3 vitexin galactoside 4 ). All identified by HR‐ESI‐MS in‐depth NMR‐spectroscopic analyses. In antiviral assays, compound was found...
Flavone C-glycosides are difficult to be deglycosylated using traditional chemical methods due their solid carbon-carbon bond between sugar moieties and aglycones; however, some bacteria may easily cleave this because they generate various specific enzymes.A bacterial strain, named W12-1, capable of deglycosylating orientin, vitexin, isovitexin aglycones, was isolated from human intestinal in study identified as Enterococcus faecalis based on morphological examination, physiological...