Sadik Taju Sherief

ORCID: 0000-0003-4614-4563
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About
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Research Areas
  • Ocular Oncology and Treatments
  • Global Maternal and Child Health
  • Intraocular Surgery and Lenses
  • Nonmelanoma Skin Cancer Studies
  • Glaucoma and retinal disorders
  • Corneal surgery and disorders
  • Ophthalmology and Visual Health Research
  • Corneal Surgery and Treatments
  • Brain Metastases and Treatment
  • Ophthalmology and Eye Disorders
  • Reproductive tract infections research
  • Ophthalmology and Visual Impairment Studies
  • Cancer-related Molecular Pathways
  • Retinopathy of Prematurity Studies
  • Retinal Diseases and Treatments
  • Ethnobotanical and Medicinal Plants Studies
  • Complementary and Alternative Medicine Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Ocular Diseases and Behçet’s Syndrome
  • Neonatal Respiratory Health Research
  • Adolescent Sexual and Reproductive Health
  • Epigenetics and DNA Methylation
  • Cerebral Venous Sinus Thrombosis
  • Traumatic Ocular and Foreign Body Injuries
  • Neonatal Health and Biochemistry

Addis Ababa University
2011-2024

Bangladesh Islami University
2024

University of Toronto
2018-2023

Hospital for Sick Children
2018-2023

SickKids Foundation
2018-2023

Great Ormond Street Hospital
2018

University College London
2018

Oromiyaa Regional Health Bureau
2016

Objective The aim of this study was to determine the prevalence, causes ocular disorders and visual impairment among preterm children previously admitted neonatal intensive care units in Addis Ababa, Ethiopia. Methods analysis A prospective screening survey conducted from February June 2019 at paediatric eye clinic Menelik II Hospital. Children who were birth attended included study. Data on demographic characteristics, maternal comorbidities collected. OR univariate used identify predictors...

10.1136/bmjpo-2023-002317 article EN cc-by BMJ Paediatrics Open 2024-02-01

Purpose: We aimed to estimate the prevalence of trachoma in each district ("woreda") Tigray Region, Ethiopia.Methods: conducted 11 cross-sectional community-based surveys evaluation units covering 34 rural woredas from January March 2013 using standardized methodology developed for Global Trachoma Mapping Project.Results: Teams visited 8034 households 275 villages. A total 28,581 consenting individuals were examined, 16,163 (56.7%) whom female. The region-wide adjusted trichiasis was 1.7%...

10.1080/09286586.2016.1250917 article EN cc-by-nc-nd Ophthalmic Epidemiology 2016-12-05

Background: The relationship between lag time and outcomes in retinoblastoma (RB) is unclear. In this study, we aimed to study the effect of onset symptoms diagnosis countries based on their national-income analyse its outcomes. Methods: We performed a prospective 692 patients from 11 RB centres 10 1 January 2019 31 December 2019. Results: following factors were significantly different among level: age at (p = 0.001), distance home nearest primary healthcare centre 0.03) mean detection first...

10.3390/cancers13081956 article EN Cancers 2021-04-19

To investigate in a large global sample of patients with retinoblastoma whether sex predilection exists for this childhood eye cancer.A cross-sectional analysis including 4351 treatment-naive from 153 countries who presented to 278 treatment centers across the world 2017. The ratio (male/female) was compared at birth by means two-sided proportions test level, country economic grouping, continent, and selected countries.For entire sample, mean ratio, 1.20, higher than weighted birth, 1.07 (p...

10.1038/s41433-021-01675-y article EN cc-by Eye 2021-07-16

Abstract Background Increased lag time between the onset of symptoms and treatment retinoblastoma (RB) is one factors contributing to delay in diagnosis. The aim this study was understand referral patterns times for RB patients who were treated at Menelik II Hospital Addis Ababa, Ethiopia. Method A single-center, cross- sectional conducted January 2018. All new with a confirmed diagnosis had presented from May 2015 2017 eligible. questionnaire developed by research team administered...

10.1186/s12913-023-09137-9 article EN cc-by BMC Health Services Research 2023-02-20

Introduction: The presenting symptoms of retinoblastoma in Ethiopia, as well their relationship to the stage disease, are poorly understood, but they could be important background knowledge for creating early detection initiatives. This study aimed describe clinical and histopathological characteristics among Ethiopian patients. Methods: A hospital-based cross-sectional analysis all children with newly diagnosed during period May 2015 December 2019, inclusive, who presented a tertiary...

10.1159/000525113 article EN Ocular Oncology and Pathology 2022-01-01

Purpose While progress was made towards the Vision 2020: The Right to Sight goals, Ethiopia, Ghana, and Zambia fell short of recommended cataract surgical rate (CSR) on a national level. Post-operative outcomes are also lower compared other regions. This study aimed describe perceived barriers uptake, factors related surgeon productivity, offerings in each these countries.

10.1080/09286586.2023.2301581 article EN Ophthalmic Epidemiology 2024-01-18

Traditional medicines are commonly used worldwide, especially in Africa-however, there is limited information on the prevalence and types of traditional eye medicine utilization Ethiopia. The goal this study was to determine prevalence, type nature use practices related self-medication for ophthalmic diseases a rural Ethiopian population.

10.1186/s12906-024-04565-4 article EN cc-by BMC Complementary Medicine and Therapies 2024-07-04

The purpose of this study is to describe the clinical characteristics, microscopic findings, and treatment response albendazole microsporidial keratoconjunctivitis among immunocompromised individuals with HIV/AIDS.This a retrospective case series. Diagnosis was confirmed by subspecialist examination conjunctival swabs examined light microscopy. HIV infection documented, absolute CD4+ T cell count determined. Patients were treated followed for response.Light microscopy from demonstrated...

10.1007/s12348-011-0025-y article EN cc-by Journal of Ophthalmic Inflammation and Infection 2011-05-10

Abstract Background Educational capacity building in pediatric ophthalmology is necessary to address the burden of childhood blindness Ethiopia. Residency and fellowship training at Addis Ababa University (AAU) have been enhanced with support from Toronto (UofT), following established Academic Collaboration (TAAAC). Our aim was assess feasibility implementing a AAU UofT, modeled by successful postgraduate medical education within TAAAC. Methods A situational analysis, including needs...

10.1186/s12909-020-02368-y article EN cc-by BMC Medical Education 2020-11-16

Background Rates of care abandonment for retinoblastoma (RB) demonstrate significant geographical variation; however, other variables that place a patient at risk abandoning remain unclear. This study aims to identify the factors across multinational set patients. Methods A prospective, observational 692 patients from 11 RB centres in 10 countries was conducted 1 January 2019 31 December 2019. Multivariate logistic regression used associated with higher rates abandonment. Results Logistic...

10.1136/bjo-2022-321159 article EN British Journal of Ophthalmology 2022-09-16

Purpose: A community-based study was conducted to determine the prevalence and sociodemographic factors of pseudoexfoliation syndrome among adults in Southern Ethiopia. Patients Methods: cross-sectional subjects aged 40 years or older. Subjects underwent standardized examination, including portable slit-lamp biomicroscopy before after pupillary dilatation, intraocular pressure measurement using Tono-Pen. Pseudoexfoliation diagnosed on examination by presence white dandruff-like material...

10.2147/opth.s391290 article EN cc-by-nc Clinical ophthalmology 2022-11-01

The majority of childhood blindness causes in low-income countries are treatable or avoidable. Parents guardians responsible for making decisions regarding a child's eye care. Understanding parents' awareness and perception problems crucial helping to know care-seeking behavior.To determine parental knowledge, attitudes practice child health.Seven focus groups were carried out Northwest Ethiopia on attitude parents towards health. Their responses tape-recorded later transcribed. A thematic...

10.1371/journal.pone.0293595 article EN cc-by PLoS ONE 2023-11-03

This study explored the lived experience of parents children with retinoblastoma.A phenomenological qualitative design was used, and a purposive sampling technique to recruit retinoblastoma. Semi-structured interviews were conducted document participants, who asked narrate their experiences caring for child retinoblastoma, thinking back day they learned about child's condition, as well thoughts future. The in Amharic Oromo language, audio recordings transcribed translated English. Data...

10.1002/pbc.30163 article EN Pediatric Blood & Cancer 2022-12-22

Purpose: The prevalence of trichiasis is higher in females and increases markedly with age. Surveys carried out the daytime, particularly developing countries, are prone to find older individuals at home time survey. Population-level estimates should adjust sample proportions reflect demographic breakdown population, although most accurate method doing this unclear.Methods: Having obtained data from 162 surveys Ethiopia as part Global Trachoma Mapping Project 2012 2015, we used internal...

10.1080/09286586.2018.1555262 article EN cc-by Ophthalmic Epidemiology 2018-12-28

This study was conducted to determine the prevalence and risk factors for retinopathy of prematurity (ROP) in two neonatal intensive care units (NICUs) Addis Ababa, Ethiopia.A prospective screening survey from June 2019 2020 level 3 public NICUs. Infants with a birth weight (BW) ≤1500 g or gestational age (GA) ≤32 weeks those BW >1500 GA >32 an unstable clinical course were included. Data on demographic characteristics, maternal comorbidities, therapeutic interventions collected. Logistic...

10.1136/bmjophth-2023-001257 article EN cc-by-nc BMJ Open Ophthalmology 2023-07-01

To investigate the outcomes of primary enucleation and adjuvant systemic chemotherapy, when deemed appropriate, on a cohort children with unilateral intraocular Rb (AJCC 8th edition, cT2 cT3) from diverse economic groupings. A prospective analysis including treatment-naïve patients were presented to 11 centers 10 countries January 1 December 31, 2019, followed-up thereafter. Only that underwent included in present analysis. Systemic metastasis survival investigated. Of 692 Rb, 191 (27.6%)...

10.1080/08820538.2024.2447724 article EN Seminars in Ophthalmology 2024-12-31

The protective effects of breastfeeding on various childhood malignancies have been established but an association has not yet determined for retinoblastoma (RB). We aimed to further investigate the role in severity nonhereditary RB development, assessing relationship (1) age at diagnosis, (2) ocular prognosis, measured by International Intraocular Classification (IIRC) or (ICRB) group and success eye salvage, (3) extraocular involvement. Analyses were performed a global dataset subgroup 344...

10.3390/cancers13194773 article EN Cancers 2021-09-24

The aim of this study was to document the available resources and needs for detection, diagnosis, treatment retinoblastoma (RB) in Ethiopia.A health services assessment focused on RB care Ethiopia conducted. Information obtained through a web-based survey field visits. Facilities offering service delivery were categorized into three tiers, basis ability detect (tier 1) manage simple 2) or complex 3) patients with RB. Descriptive statistics performed quantify human material at each...

10.1200/go.22.00445 article EN cc-by-nc-nd JCO Global Oncology 2023-06-01

Background Child eye health is a serious public issue in Ethiopia, where children under the age of 15 account for over half population. Our aim was to review Ethiopian policy and practice reveal approaches commitment promotion delivery child services. Methods We conducted mixed-methods situational analysis employing documentary key informant interview methods. Government publications touching on any element were included. Key informants eligible if they leaders, authorities, researchers or...

10.1136/bmjopen-2023-075622 article EN cc-by-nc BMJ Open 2023-11-01

Abstract Introduction Retinoblastoma is the most frequent intraocular malignancy of eye in children, occurring early childhood. Based on global estimates, Ethiopia expected to observe over 200 new retinoblastoma cases per year, however without a cancer registry, this number difficult confirm. Therefore, goal study was determine incidence and geographic distribution Ethiopia. Methods A retrospective medical chart review clinically diagnosed patients between January 1, 2017 - December 31,...

10.1186/s12886-023-02980-8 article EN cc-by BMC Ophthalmology 2023-05-23

Abstract Background Bilateral cataract is a significant cause of blindness in children Ethiopia. This study aimed to identify the resources available for surgery children, and assess current surgical practices, output factors affecting outcome Methods A Google Forms mobile phone questionnaire was emailed nine ophthalmologists known perform young (0–5 years). Results All responded. but one had received either 12- or 3–5-month’s training pediatric ophthalmology with hands-on training. The...

10.1186/s12886-021-02190-0 article EN cc-by BMC Ophthalmology 2021-12-01
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