Shaohua Liu

ORCID: 0000-0003-4626-7037
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About
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Research Areas
  • Spinal Fractures and Fixation Techniques
  • Infectious Diseases and Tuberculosis
  • Scoliosis diagnosis and treatment
  • Spine and Intervertebral Disc Pathology
  • Shoulder Injury and Treatment
  • Orthopedic Infections and Treatments
  • Knee injuries and reconstruction techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pelvic and Acetabular Injuries
  • Shoulder and Clavicle Injuries
  • Sports injuries and prevention
  • Intensive Care Unit Cognitive Disorders
  • Total Knee Arthroplasty Outcomes
  • Tuberculosis Research and Epidemiology
  • Anesthesia and Sedative Agents
  • Anesthesia and Neurotoxicity Research
  • Hip disorders and treatments
  • Cervical and Thoracic Myelopathy
  • Tendon Structure and Treatment
  • Medical Imaging and Analysis
  • Congenital Diaphragmatic Hernia Studies
  • Airway Management and Intubation Techniques
  • Amoebic Infections and Treatments
  • Orthopaedic implants and arthroplasty
  • Spinal Dysraphism and Malformations

Xiangya Hospital Central South University
2013-2024

Central South University
2013-2024

National Clinical Research
2022-2024

Huashan Hospital
2016-2023

Fudan University
2016-2023

Huazhong University of Science and Technology
2012-2023

Tongji Hospital
2023

National Clinical Research Center for Digestive Diseases
2023

Second Xiangya Hospital of Central South University
2022-2023

Zhengzhou University
2023

This study aimed to evaluate the impact of precise treatment administered according results metagenomic next-generation sequencing (mNGS) on clinical outcomes patients with spinal infections. In this multicenter retrospective study, data 158 infections who were admitted Xiangya Hospital Central South University, Boai Rehabilitation Hospital, The First Changsha, and Hunan Chest from 2017 2022 reviewed. Among these patients, 80 treated targeted antibiotics mNGS assigned medicine (TM) group....

10.3389/fcimb.2023.1076525 article EN cc-by Frontiers in Cellular and Infection Microbiology 2023-02-08

Corticosteroid injection is a common treatment for frozen shoulder, but controversy still exists regarding the site with best outcome.To treat shoulder in freezing stage corticosteroid injection, single into rotator interval (RI) could yield better effects terms of improvement pain, passive range motion (ROM), and function than would an intra-articular (IA) or subacromial (SA) space.Randomized controlled trial; Level evidence, 1.Patients primary were randomized 3 groups: RI IA SA...

10.1177/0363546517744171 article EN The American Journal of Sports Medicine 2017-12-21

Background: The hamstring tendons are commonly harvested for anterior cruciate ligament (ACL) reconstruction with detachment of the tibial insertion. Retaining insertion may help to preserve vascularity and viability graft bypass stages avascular necrosis revascularization, which might be beneficial maturity. Purpose: To investigate compare maturity by magnetic resonance imaging (MRI) after ACL preservation or tendon at up 2 years. Study Design: Randomized controlled trial; Level evidence,...

10.1177/0363546517752918 article EN The American Journal of Sports Medicine 2018-02-14

Background Early antimicrobial therapy is crucial regarding the prognosis of vertebral osteomyelitis, but early pathogen diagnosis remains challenging.

10.1080/07853890.2024.2337738 article EN cc-by-nc Annals of Medicine 2024-04-08

Background: Graft bridging is used in massive rotator cuff tear (MRCT); however, the integration of graft-tendon and graft-bone still a challenge. Hypothesis: A co-electrospinning nanoscaffold polycaprolactone (PCL) with an “enthesis-mimicking” (EM) structure could bridge MRCT, facilitate tendon regeneration, improve healing. Study Design: Controlled laboratory study. Methods: First, we analyzed cytocompatibility electrospinning nanoscaffolds, including aligned PCL (aPCL), nonaligned (nPCL),...

10.1177/0363546520917684 article EN The American Journal of Sports Medicine 2020-05-26

Osteopenia have been well documented in adolescent idiopathic scoliosis (AIS). Adiponectin has shown to be inversely proportional body mass index and affect bone metabolism. However, the circulating levels of adiponectin relationship between low AIS remain unclear. A total 563 281 age-matched controls were recruited for this study. Anthropometry measured all participants. Plasma determined by enzyme-linked immunosorbent assay (ELISA) control groups. An improved multiplex ligation detection...

10.1186/s12967-019-1805-7 article EN cc-by Journal of Translational Medicine 2019-02-28

Background: The semitendinosus tendon graft with an intact tibial insertion has a sustainable blood supply and might be beneficial for maturation after anterior cruciate ligament reconstruction (ACLR); however, its potential advantages tendon-bone healing is still unclear. Hypothesis: Intact of the hamstring can preserve enough to keep harvested alive, which improve biomechanical strength graft. Study Design: Controlled laboratory study. Methods: Sixty-four healthy New Zealand White rabbits...

10.1177/0363546518799357 article EN The American Journal of Sports Medicine 2018-10-04

Graft healing within the femoral tunnel after anterior cruciate ligament reconstruction (ACLR) using suspensory fixation could be reflected in graft maturation and morphological changes. However, correlation between changes remains unclear.To quantitatively evaluate to analyze their ACLR cortical suspension.Case series; Level of evidence, 4.Patients who underwent single-bundle with a hamstring tendon autograft suspension were included. Preoperative postoperative (at 6, 12, 24 months) knee...

10.1177/0363546519898136 article EN The American Journal of Sports Medicine 2020-01-22

Background: It has been reported that insertion-preserved hamstring tendon autografts (IP-HT) have better maturity than free (FHT) at 2 years after anterior cruciate ligament reconstruction (ACLR); however, whether insertion preservation improves the of entire autograft and clinical outcomes 5 ACLR is still unclear. Purpose: To investigate different segments using up to ACLR. Study Design: Randomized controlled trial; Level evidence, 2. Methods: 45 patients who underwent isolated with were...

10.1177/0363546520951507 article EN The American Journal of Sports Medicine 2020-09-10

OBJECT The object of this study was to evaluate the efficacy and safety posterior decompression with kyphosis correction for thoracic myelopathy due ossification ligamentum flavum (OLF) longitudinal ligament (OPLL) at same level. METHODS Between January 2003 December 2005, 11 patients (8 men 3 women) OLF OPLL level underwent decompressive laminectomy excision OLF. Posterior instrumentation also performed stabilization spine reducing angle by approximately 5-15 degrees (kyphosis correction),...

10.3171/2010.3.spine09237 article EN Journal of Neurosurgery Spine 2010-07-01

OBJECTIVE The objective of this study was to evaluate the clinical efficacy posterior-only surgical correction dystrophic scoliosis in patients with neurofibromatosis Type 1 (NF1) using a multiple anchor point method (MAPM). METHODS From 2005 2014, 31 (mean age 13.5 years old, range 10-22 old) suffering from associated NF1 underwent MAPM. apex deformity thoracic (n = 25), thoracolumbar 4), and lumbar 2). mean preoperative coronal Cobb angle 69.1° (range 48.9°-91.4°). on side-bending...

10.3171/2016.7.peds16125 article EN Journal of Neurosurgery Pediatrics 2016-10-14

Background: Quantitative ultrashort echo time–T2* (UTE-T2*) mapping shows promise for the detection of potential tendon biochemical conditions, while validation against established clinical studies in shoulder is needed. Purpose: To evaluate and characterize healing process repaired rotator cuff based on longitudinal changes UTE-T2* values, outcomes, repair status patients after arthroscopic (ARCR). Study Design: Cohort study; Level evidence, 2. Methods: Patients with ARCR (n = 25) underwent...

10.1177/0363546520946772 article EN The American Journal of Sports Medicine 2020-08-19

To investigate the association between SLC11A1 (NRAMP1) rs17235409 (D543N) polymorphisms and susceptibility to spinal tuberculosis (STB) in Han population southern China. This study included 227 STB patients 516 controls. Polymorphisms of were genotyped using a SNPscan™ kit, protein was detected by western blotting. The genotype allele frequency distributions differed significantly group control group(χ2 = 17.650, P 0.000). distribution GA genotype(GA vs. GG: 0.000, OR [95% CI]...

10.1016/j.meegid.2021.105202 article EN cc-by-nc-nd Infection Genetics and Evolution 2022-01-03

Background Early diagnosis of spinal tuberculosis (STB) remains challenging. The aim this study was to develop a predictive model for the early STB based on conventional laboratory indicators. Method clinical data patients with suspected in four hospitals were included, and variables screened by Lasso regression. Eighty-five percent cases dataset randomly selected as training set, other 15% validation set. diagnostic prediction established logistic regression nomogram drawn. performance...

10.3389/fcimb.2023.1150632 article EN cc-by Frontiers in Cellular and Infection Microbiology 2023-03-24
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