A5100689470- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Knee injuries and reconstruction techniques
- Multiple and Secondary Primary Cancers
- Total Knee Arthroplasty Outcomes
- Renal and related cancers
- Radiomics and Machine Learning in Medical Imaging
- Thyroid Cancer Diagnosis and Treatment
- Adenosine and Purinergic Signaling
- Cancer, Lipids, and Metabolism
- Economic and Financial Impacts of Cancer
- Tendon Structure and Treatment
- Chronic Kidney Disease and Diabetes
- Pain Mechanisms and Treatments
- Neuroscience of respiration and sleep
- Advanced biosensing and bioanalysis techniques
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Pediatric Urology and Nephrology Studies
- Silk-based biomaterials and applications
- CRISPR and Genetic Engineering
- RNA Interference and Gene Delivery
- Cardiac Valve Diseases and Treatments
- Cervical Cancer and HPV Research
- Ferroptosis and cancer prognosis
University of California, San Diego
2018-2025
Inner Mongolia Agricultural University
2019-2025
Guiyang Medical University
2016-2025
Women's Hospital, School of Medicine, Zhejiang University
2013-2025
Beijing University of Chinese Medicine
2025
Zhejiang University
2025
Affiliated Hospital of Guizhou Medical University
2016-2025
Jingchu University of Technology
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2000-2024
Jilin University
2007-2024
The alteration of craniofacial structures has been associated with obstructive sleep apnoea (OSA). We hypothesised that: 1) a smaller mandible is risk factor for OSA; and 2) the previously observed inferiorly positioned hyoid bone in apnoeics enlarged tongue volume. This case-control study using three-dimensional magnetic resonance imaging cephalometry. 55 apneics controls were matched age, sex race. analysis was stratified by controlled race, height, neck visceral fat, skeletal type found...
Electricity generation from flowing water has been developed for over a century and plays critical role in our lives. Generally, heavy complex facilities are required electricity generation, while using these technologies applications that require small size high flexibility is difficult. Here, we fluidic nanogenerator fiber an aligned carbon nanotube sheet to generate any source the environment as well human body. The power conversion efficiency reached 23.3 %. was flexible stretchable,...
We used oligonucleotide microarrays to investigate gene expression changes associated with multi-step human papillomavirus type 16 (HPV16)-mediated carcinogenesis in vitro. Gene profiles 4 early passage HPV16-immortalized keratinocyte (HKc) lines derived from different donors were compared their corresponding late-passage, differentiation-resistant cell lines, and pools of normal HKc, each composed 3 individual HKc strains, on Agilent 22 k microarrays. The resulting data analyzed using a...
Background Thyroid cancer is the most common malignancy of endocrine system worldwide. Papillary thyroid (PTC) pathologic type. The preoperative diagnosis PTC and central lymph node metastasis (CLNM) or metastatic tendency great clinical significance to diagnosis, treatment prognosis these patients. This study was conducted investigate correlation between ultrasound features CLNM PTC. Methods retrospectively analyzed patients who underwent surgery dissection in Department Surgery, Beijing...
Artificial intelligence (AI) has become one of the core driving forces for future development medical industry, but patients are skeptical about use AI in care. Based on intergroup threat theory (ITT), this study verified that would regard as an external group, triggering perceived which results avoidance behaviors treatment (experiment 1: n = 446) and diagnosis 2: 330) scenarios. The show despite can provide expert-level accuracy care, still more likely to rely human doctors experience...
Background HIV remains a major challenge in KwaZulu-Natal, South Africa, particularly for young women who face disproportionate risks and barriers to prevention treatment. Most cure trials, however, occur high-income countries.
Current trials toward an HIV cure involve combination strategies aimed at achieving durable antiretroviral treatment (ART)-free viral control or elimination, many relying on analytical interruptions (ATIs) to evaluate efficacy. Given the physical, psychosocial, and interpersonal risks associated with ATIs, it is critical monitor participants' experiences so that support can be provided when needed. While qualitative approaches have been used in similar settings, we designed implemented a...
Exposure to endocrine disrupting chemicals (EDCs), particularly benzophenone (BP)-type UV filters, has been epidemiologically linked endometrium-related reproductive risks in women. However, their effects on hormone-driven endometrial events and key receptor signaling at the human cellular level remain unexplored. Herein, using primary stromal cells (HESCs), we investigated of five BP congeners deciphered underlying mechanism decidualization, a functional change endometrium preparing for...
Background: Glioblastoma is “cold”. Consequently, immune checkpoint blockade therapy has failed to improve patients‘ survival, which negatively correlated with patients’ peripheral MDSC counts. AHR known mediate immune-suppressive functions of certain tryptophan metabolites such as kynurenine; yet, there lack reports on how agonists affect glioma immunity. Methods/Objectives: We hypothesized that ITE could synergize PD1 antibody one major node pathways, and tested it using an...
Background Etoposide-induced protein 2.4 (EI24), an essential component of autophagy, is lowly expressed in pulmonary fibrosis. Hesperidin (Hes), a flavonoid, can regulate autophagy various diseases. However, whether Hes inhibit fibrosis by mechanically regulating EI24-mediated has not been uncovered.
Zika virus (ZIKV) infection is associated with microcephaly in newborns and serious neurological complications adults. Apoptosis of neural progenitor cells induced by ZIKV believed to be a main reason for infection-related microcephaly. However, the detailed mechanism infection-induced apoptosis remains elucidated. In this report, conformational activation pro-apoptotic protein Bax, subsequent formation oligomers Bax mitochondria. Cell was reduced significantly SY5Y subjected knockdown....
Six1, a member of the Six family homeodomain transcription factors, is overexpressed in various human cancers, and SIX1 overexpression associated with tumor progression metastasis. Six1 messenger RNA levels increase during vitro papillomavirus type 16 (HPV16)-immortalized keratinocytes (HKc/HPV16) toward differentiation-resistant (HKc/DR) phenotype. In this study, we show that HKc/DR-overexpressing exhibited more mesenchymal phenotype, as characterized by fibroblastic appearance increased...
Panaxatriol saponins (PTS), the main components extracted from Panax notoginseng , have been shown to be efficacious in prevention and treatment of cerebrovascular diseases China. NF-E2-related factor 2 (Nrf2), a transcription regulating antioxidant cytoprotective responses oxidative stress, has received particular attention as molecular target for pharmacological intervention ischemic diseases. The aim this study was characterize effect PTS on activation Nrf2 signaling pathway potential...
Increased platelet aggregation is implicated in the pathogenesis of ischemic stroke and anti-platelet strategy may contribute to its therapy. Panaxatriol saponin (PTS), main components extracted from Panax notoginseng, has been shown be efficacious prevention treatment China. The aim this study determine activity explore underlying mechanisms.Inhibitory effect PTS ginsenosides on agonists-induced was determined using rabbit or human platelets. Intracellular Ca(2+) concentration ([Ca(2+)]i)...
This meta-analysis was performed to systematically assess the efficacy and safety of Chinese herbal medicine Huangqi Guizhi Wuwu Decoction (HGWWD) for treating diabetic peripheral neuropathy.Six electronic databases, including Cochrane Library, MEDLINE database, Biomedical Database, National Knowledge Infrastructure Science Technique Journals Wanfang were searched on internet randomized controlled trials published up until 1 December 2015. The search terms included "Chinese medicine",...
Background: Application of artificial ligament in anterior cruciate reconstruction is one the research focuses sports medicine but biological tendon–bone healing still remains a problem. The preliminary study hydroxyapatite (HAP) coating on polyethylene terephthalate (PET) surface could effectively induce osteoblast differentiation, was not stable. As green synthesis process, biomimetic mineralization can simulate natural bone growth vitro and vivo. Methods: HAP crystals were grown under...
In order to clarify the risk of hematotoxicity carboplatin, we inspected 19901 case reports non-small cell lung cancer patients that were submitted FDA Adverse Event Reporting System (FAERS) between January 2004 and December 2015. These comprised 3907 cases which treated with carboplatin 15994 other therapies in absence carboplatin. By comparison, significantly more likely report anemia (OR = 2.27, 95% CI 1.85-2.78, P 5.04×10-15), neutropenia 1.76-2.92, 2.39×10-10), thrombocytopenia 2.38,...
Background: The semitendinosus tendon graft with an intact tibial insertion has a sustainable blood supply and might be beneficial for maturation after anterior cruciate ligament reconstruction (ACLR); however, its potential advantages tendon-bone healing is still unclear. Hypothesis: Intact of the hamstring can preserve enough to keep harvested alive, which improve biomechanical strength graft. Study Design: Controlled laboratory study. Methods: Sixty-four healthy New Zealand White rabbits...