- Neural dynamics and brain function
- Visual perception and processing mechanisms
- Neurobiology and Insect Physiology Research
- Neuroscience and Neural Engineering
- Advanced Sensor and Energy Harvesting Materials
- Retinal Development and Disorders
- Tactile and Sensory Interactions
- Dental Anxiety and Anesthesia Techniques
- Conducting polymers and applications
- Photoreceptor and optogenetics research
- EEG and Brain-Computer Interfaces
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Neuroscience and Neuropharmacology Research
- Optical Imaging and Spectroscopy Techniques
- Pain Mechanisms and Treatments
- Color perception and design
- Morphological variations and asymmetry
- Bone Tissue Engineering Materials
- Laser Applications in Dentistry and Medicine
- Color Science and Applications
- Endodontics and Root Canal Treatments
- Photoacoustic and Ultrasonic Imaging
- Occupational health in dentistry
- Dental Implant Techniques and Outcomes
Fudan University
2016-2025
State Key Laboratory of Medical Neurobiology
2016-2024
University of Science and Technology of China
2000-2008
Gamma rhythms in many brain regions, including the primary visual cortex (V1), are thought to play a role information processing. Here, we report surprising finding of 3 narrowband gamma V1 that processed distinct spatial frequency (SF) signals and had different neural origins. The low (LG; 25 40 Hz) rhythm was generated at superficial layer preferred higher SF compared with spike activity, whereas both medium (MG; 65 Hz), cortical level, high HG; (65 85 originated precortically, lower...
Sensitivity to motion direction is a feature of visual neurons that essential for perception. Recent studies have suggested selectivity re-established at multiple stages throughout the hierarchy, which contradicts traditional assumption in later largely derives from earlier stages. By recording laminar responses areas 17 and 18 anesthetized cats both sexes, we aimed understand how processed relayed across 2 successive stages: input layers output within early cortices. We found strong...
Implantable neural devices that record neurons in various states, including static light activities such as walking, and vigorous running, offer opportunities for understanding brain functions dysfunctions. However, recording under remains a long-standing challenge because it leads to intense deformation. Thus, three key requirements are needed simultaneously devices, is, low modulus, specific interfacial impedance, high electrical conductivity, realize stable device/brain interfaces...
Stimulus-dependence of gamma oscillations (GAMMA, 30-90 Hz) has not been fully understood, but it is important for revealing neural mechanisms and functions GAMMA. Here, we recorded spiking activity (MUA) the local field potential (LFP), driven by a variety plaids (generated two superimposed gratings orthogonal to each other with different contrast combinations), in primary visual cortex anesthetized cats. We found distinct narrow-band GAMMAs LFPs response patterns plaids. Similar MUA, most...
Black and white information is asymmetrically distributed in natural scenes, evokes asymmetric neuronal responses, causes perceptions. Recognizing the universality essentiality of black-white asymmetry visual processing, neural substrates for remain unclear. To disentangle role feedforward recurrent mechanisms generation cortical asymmetry, we recorded V1 laminar responses LGN anesthetized cats both sexes. In a column, found that starts at input layer becomes more pronounced output layer. We...
Abstract The extracellular potassium ion concentration in the brain exerts a significant influence on cellular excitability and intercellular communication. Perturbations level are closely correlated with various chronic neuropsychiatric disorders including depression. However, critical gap persists performing real‐time long‐term monitoring of ions, which is necessary for comprehensive profiling diseases. Here, fiber sensor (FKS) that consists soft conductive rough surface...
Adaptation plays a key role in visual information processing, and investigations on the adaptation across different regions will be helpful to understand how is processed dynamically along streams. Recent studies have found enhanced effects early system (from LGN V1) dorsal stream V1 MT). However, it remains unclear effect propagates form/orientation system. In this study, we compared orientation direction evoked by drifting gratings stationary flashing gratings, as well moving random dots,...
The visual system is organized in a parallel and hierarchical architecture. However, the plasticity neural networks controversial across different response features at levels. In this study, we recorded areas 17 21a, earlier intermediate stages of cortex cat, respectively, by single-unit recording intrinsic-signal optical imaging. We found that ocular dominance (OD) evoked monocular deprivation (MD) was stronger area 21a than critical period (CP), became weaker but still persisted while it...
Dark adaptation can induce a rapid functional shift in the retina, and after that, retinal function is believed to remain stable during continuous dark exposure. However, we found that electroretinograms (ERG) b-waves gradually shifted 24 hours' exposure rodents. Detailed experiments were designed explore this non-classical adaptation.In vivo ERG recording adult developing rodents light manipulations.We revealed five-fold decrease rats exposed for hours. The significantly increased within...
This study aimed to investigate the cortical response characteristics evoked by natural teeth and implants.Five cats were subjected intrinsic signal optical imaging measure responses implants. The difference in tactile sensation between implant tooth was compared detail at level.Some similarities observed implants teeth. stimulating-response curves of generally S-curves, both preferred labial-lingual direction stimulation. differed terms their sensitivity: weaker than static dynamic...