- Head and Neck Surgical Oncology
- Medical Imaging Techniques and Applications
- Head and Neck Cancer Studies
- Cerebrospinal fluid and hydrocephalus
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Salivary Gland Tumors Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Sinusitis and nasal conditions
- Medical Imaging and Analysis
- Glioma Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Meningioma and schwannoma management
- Intracranial Aneurysms: Treatment and Complications
- Advanced MRI Techniques and Applications
- Head and Neck Anomalies
- Traumatic Brain Injury and Neurovascular Disturbances
- Fetal and Pediatric Neurological Disorders
- Vascular Malformations Diagnosis and Treatment
- Ear and Head Tumors
- Cerebral Venous Sinus Thrombosis
- Neurosurgical Procedures and Complications
- Spinal Dysraphism and Malformations
- Tumors and Oncological Cases
- Cerebrovascular and Carotid Artery Diseases
Moffitt Cancer Center
2022-2025
Johns Hopkins Hospital
2008-2022
Johns Hopkins University
2013-2022
Johns Hopkins Medicine
2007-2022
Siemens Healthcare (United States)
2015
Carestream (United States)
2015
Uppsala University
2014
Hanover College
2014
Gendarmerie Nationale
2005
Cleveland Clinic
2002
In image-guided spine surgery, robust three-dimensional to two-dimensional (3D-2D) registration of preoperative computed tomography (CT) and intraoperative radiographs can be challenged by the image content mismatch associated with presence surgical instrumentation implants as well soft-tissue resection or deformation. This work investigates similarity metrics in 3D-2D offering improved robustness against mismatch, thereby improving performance reducing eliminating need for manual masking....
To assess the safety of 1.5 T magnetic resonance imaging (MRI) in patients with cochlear implants (CIs) internal magnets.Retrospective review CI who underwent an MRI at Johns Hopkins.Sixteen a mean age 43 ± 22 years total clinically indicated MRI. Devices from 3 major manufactures were represented.Binding mold material and gauze was performed before Some also administered sedative. Intravenous gadolinium contrast used all but 1 patient.Patients assessed regard to ability complete MRI, size...
CT is the frontline imaging modality for diagnosis of acute traumatic brain injury (TBI), involving detection fresh blood in (contrast 30-50 HU, detail size down to 1 mm) a non-contrast-enhanced exam. A dedicated point-of-care system based on cone-beam (CBCT) could benefit early TBI and improve direction appropriate therapy. However, flat-panel detector (FPD) CBCT challenged by artifacts that degrade contrast resolution limit application soft-tissue imaging. We present evaluate fairly...
<h3>Background</h3> Joubert syndrome is a clinically and genetically heterogeneous ciliopathy. Neuroimaging findings have not been systematically evaluated in large cohort of patients with correlation molecular genetic cause cognitive function. <h3>Methods</h3> Brain MRI 110 was included this study. A comprehensive evaluation brain studies for infratentorial supratentorial morphological abnormalities performed. Genetic identified by whole-exome sequencing, functions were assessed...
Background The benefit of immune checkpoint inhibitors (ICIs) in patients with leptomeningeal metastases (LMM) is unknown. Methods We undertook a phase II trial pembrolizumab LMM from solid tumors. Eligible had radiologic/cytologic and Eastern Cooperative Oncology Group performance status 0–1. Pembrolizumab was administered intravenously at 200 mg q3W until disease progression/unacceptable toxicity. primary endpoint central nervous system (CNS) response after four cycles, defined...
Abstract Objective 18F‐Fluorodeoxyglucose positron emission tomography (FDG‐PET) is widely used in presurgical assessment patients with drug‐resistant focal epilepsy (DRE) if magnetic resonance imaging (MRI) and scalp electroencephalography (EEG) do not localize the seizure onset zone or are discordant. Methods In this multicenter, retrospective observational cohort study, we included consecutive DRE who had undergone FDG‐PET as part of their workup. We assessed utility FDG‐PET, which was...
<h3>Objective</h3>To determine the value of positron emission tomography (PET) with contrast-enhanced computed (CT) in assessing need for neck dissection by retrospectively reviewing pathology reports patients human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (SCC).<h3>Design</h3>Retrospective cohort study.<h3>Setting</h3>Tertiary medical center.<h3>Patients</h3>Seventy-seven HPV-related SCC.<h3>Main Outcome Measures</h3>Seventy-seven consecutive a diagnosis SCC who...