- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Glioma Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Disease Prevention
- Peripheral Nerve Disorders
- MRI in cancer diagnosis
- Functional Brain Connectivity Studies
- Neonatal and fetal brain pathology
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Intracranial Aneurysms: Treatment and Complications
- Nerve Injury and Rehabilitation
- Dupuytren's Contracture and Treatments
- Advanced NMR Techniques and Applications
- Meningioma and schwannoma management
- Ear and Head Tumors
- Ear Surgery and Otitis Media
- Traumatic Brain Injury and Neurovascular Disturbances
- Orthopedic Surgery and Rehabilitation
- Moyamoya disease diagnosis and treatment
- Neuroblastoma Research and Treatments
- Electron Spin Resonance Studies
- Neurological Complications and Syndromes
Mayo Clinic in Florida
2023
WinnMed
2023
Johns Hopkins Hospital
2012-2022
Johns Hopkins Medicine
2012-2022
Johns Hopkins University
2011-2022
Background and Purpose— Preliminary studies suggest that intracranial arteries are capable of accommodating plaque formation by remodeling. We sought to study the ability extent remodel using 3-dimensional high-resolution black blood magnetic resonance imaging investigate its relation ischemic events. Methods— Forty-two patients with cerebrovascular events underwent time-of-flight angiography contrast-enhanced examinations at 3 T for atherosclerotic disease. Each was classified location (eg,...
Abstract Purpose To compare language networks derived from resting‐state fMRI (rs‐fMRI) with task‐fMRI in patients brain tumors and investigate variables that affect rs‐fMRI vs concordance. Materials Methods Independent component analysis (ICA) of was performed 20, 30, 40, 50 target components (ICA20 to ICA50) identified for presenting presurgical mapping between 1/1/2009 7/1/2015. 49 were analyzed fulfilling criteria presence tumors, no prior surgery, adequate performance. Rs‐vs‐task‐fMRI...
Purpose To implement a magnetic resonance (MR) imaging protocol to measure intracranial atherosclerotic disease (ICAD) in population-based multicenter study and report examination reader reliability of these MR measurements descriptive statistics representative the general population. Materials Methods This prospective was approved by institutional review boards compliant with HIPAA. Atherosclerosis Risk Communities (ARIC) participants (n = 1980) underwent brain from 2011 2013 at four ARIC...
Tumors of pineal cell origin have different prognosis and treatment than those germ origin. The recent literature suggests that these tumors often look alike. Our study aimed to differentiate between tumor germinoma based on ADC values, the homogeneity mass, MR imaging characteristics.We enrolled 20 patients who had pretreatment scans with histologic verification germinomas. were measured for values by coefficient variation T1WI T2WI signal intensity values.The subjects (8 females 12 males)...
To develop an experimental approach for determining in vivo transverse relaxation rates (T(2)) of metabolites that are detected by spectral editing without using simulations, and to demonstrate this measure the T(2) γ-aminobutyric acid (GABA).The proposed method first determines TE-dependence edited signals measurements a pure phantom solution (10 mM acid; GABA); is also determined. Once echo time (TE)-modulation pattern known, it can then be used determine vivo. The was applied GABA...
<h3>BACKGROUND AND PURPOSE:</h3> Oligodendrogliomas are tumors that have variable WHO grades depending on anaplasia and astrocytic components their treatment may differ accordingly. Our aim was to retrospectively evaluate imaging features of oligodendrogliomas predict tumor grade. <h3>MATERIALS METHODS:</h3> The studies 75 patients with were reviewed compared the histologic presence degree enhancement calcification evaluated subjectively. rCBV ADC maps measured. Logistic linear regression...
Cervical ribs are congenital variants that known to cause TOS or brachial plexopathy in up 10% of the affected individuals. We investigated how often cervical present on spine CT scans determine incidence humans and percentage reported ribs.Cervical reports 3404 consecutive adult patients were retrospectively reviewed presence whether they had been reported.Cervical found 2.0% (67/3404) population. Of 67 with ribs, 27 (40.3%) bilateral ribs. The prevalence women was twice men, 2.8% (39/1414)...
<h3>BACKGROUND AND PURPOSE:</h3> SWI is a unique pulse sequence sensitive to both hemorrhage and calcification. Our aim was retrospectively assess the ability of detect intratumoral calcification in ODs compared with conventional MR imaging. <h3>MATERIALS METHODS:</h3> Using CT as criterion standard, imaging findings from 71 patients (33 males, 38 females; mean age, 42.5 years) pathologically proved OD were evaluated. We classified data into (MRSWI) traditional sequences (MRnoSWI). The...
Purpose To measure in vivo transverse relaxation times (T 2 ) of gamma‐aminobutyric acid (GABA) at 7T using the experimental spectral‐editing method. Materials and Methods Experiments were performed a 10 mM GABA phantom to determine intrinsic TE‐dependence edited signal. Then same method was applied with editing‐based suppression coedited macromolecular signals five healthy volunteers T vivo. Results From data acquired multiple echo times, time estimated be 63 ± 19 msec. Conclusion We...
Restenosis is an important determinant of the long-term efficacy carotid endarterectomy. Our aim was to assess role high-resolution vessel wall MR imaging for characterizing restenosis after endarterectomy.Patients who underwent endarterectomy were included in this study. Restenotic lesions classified as myointimal hyperplasia or recurrent atherosclerotic plaques based on features lesion compositions. Imaging characteristics compared with those normal post-carotid and plaque groups....
Introduction: A 3D high resolution MRI (HRMRI) vascular protocol was designed to measure intracranial atherosclerosis in a biracial population from the multicenter ARIC Neurocognitive (ARIC-NCS) study. Hypothesis: HRMRI provides reliable vessel wall measurements population-based Methods: 1980 ARIC-NCS participants (mean age, 77.2±5.3 years; 40% male; 71% white, 28% black) underwent brain identify major arteries, that included time-of-flight MRA and black blood (both acquired at 0.5-mm 3...
Arterial spin labeling (ASL) is a magnetic resonance perfusion technique that allows for quantification of cerebral blood flow (CBF) without the use contrast or radiation. Several applications ASL have been described in diagnosis strokes and stroke mimics, intracranial tumors, other conditions. Various vascular anomalies exhibit specific CBF patterns correlate with different signal intensities on ASL. In this case-based review, we demonstrate utility surveillance compartment.
Abstract A standardized imaging protocol for pediatric oncology patients is essential accurate and efficient imaging, while simultaneously promoting collaborative understanding of pathologies radiologic assessment treatment response. The objective this article to provide guidelines parameters evaluation tumors the orbit, calvarium, skull base, temporal bone. This was drafted based on current scientific literature as well consensus opinions experts in collaboration with Children's Oncology...
INTRODUCTIONThe frequency of pediatric head and neck neoplasms ranges from approximately 2-15% all cancers1. Skull base calvarial neoplasms, including temporal bone orbital masses are a subset occupying number neoplastic processes categorically encompass several imaging patterns: singular dominant mass lesions with or without metastatic disease (e.g., rhabdomyosarcoma (RMS), chordoma), multifocal neuroblastoma), due to systemic malignancy leukemia, lymphoma, histiocytosis, etc.).While...