- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- CRISPR and Genetic Engineering
- Light effects on plants
- Reproductive Biology and Fertility
- Animal Genetics and Reproduction
- Epigenetics and DNA Methylation
- Virus-based gene therapy research
- Meat and Animal Product Quality
- Animal Nutrition and Physiology
- Seed Germination and Physiology
- Kruppel-like factors research
- Plant Genetic and Mutation Studies
- Genetic Syndromes and Imprinting
- Consumer Attitudes and Food Labeling
- Sensory Analysis and Statistical Methods
- Cancer-related gene regulation
- Photosynthetic Processes and Mechanisms
- Soybean genetics and cultivation
- Biochemical Analysis and Sensing Techniques
Sainsbury Laboratory
2019-2023
University of Cambridge
2019-2023
Lishui Central Hospital
2021
Northwest A&F University
2015-2016
Ministry of Agriculture and Agro Based Industry
2015
Ministry of Agriculture & Farmers Welfare
2015
University of Toronto
2011
University of Illinois Urbana-Champaign
1998
Seed germination is a complex trait of key ecological and agronomic significance. Few genetic factors regulating have been identified, the means by which their concerted action controls this developmental process remains largely unknown. Using publicly available gene expression data from Arabidopsis thaliana , we generated condition-dependent network model global transcriptional interactions (SeedNet) that shows evidence evolutionary conservation in flowering plants. The topology SeedNet...
Contents Astaxanthin is an extremely common antioxidant scavenging reactive oxygen species ( ROS ) and blocking lipid peroxidation. This study was conducted to investigate the effects of astaxanthin supplementation on oocyte maturation, development bovine somatic cell nuclear transfer SCNT embryos. Cumulus–oocyte complexes were cultured in maturation medium with (0, 0.5, 1.0, or 1.5 mg/l), respectively. We found that 0.5 mg/l significantly increased proportion maturation. Oocytes used...
Abstract Targeting exogenous genes at milk protein loci via gene-targeting technology is an ideal strategy for producing large quantities of pharmaceutical proteins. Transcription- activator-like effector (TALE) nucleases (TALENs) are efficient genome-editing tool. However, the off-target effects may lead to unintended gene mutations. In this study, we constructed TALENs and TALE nickases directed against exon 2 bovine β-lactoglobulin (BLG) locus. The can induce a site-specific DNA...
Summary Daylength is a key seasonal cue for animals and plants. In cereals, photoperiodic responses are major adaptive trait, alleles of clock genes such as PHOTOPERIOD DEPENDENT1 (PPD1) EARLY FLOWERING3 (ELF3) have been selected in breeding barley wheat more northern latitudes (Faure et al., 2012; Turner, Beales, Faure, Dunford, & Laurie, 2005). How monocot plants sense photoperiod integrate this information into growth development not well understood. We show that Brachypodium...
ABSTRACT Consumers (n = 116) evaluated color (pink intensity), appearance (wet/dry), overall acceptability and purchase intent of normal, PSE DFD pork loin slices in PVC vacuum packages. Packaging x muscle condition affected (p < 0.05) appearance, consumer slices. Color differences were perceptible to consumers between packaging treatments. PVC‐packaged was pinker than vacuum‐packaged pork. Vacuum‐packaged, appeared drier Normal more acceptable regardless packaging. not different from...
Pregnancy zone protein (PZP), a member of the proteinase inhibitor I39 (-2-macroglobulin) family proteins, is involved in initiation and development various tumors. The gene encoding PZP hypermethylated expressed at low levels hepatocellular carcinoma (HCC) tissue cells, but function HCC cells remains unclear. Here, we analyzed DNA methylation mRNA expression Cancer Genome Atlas Liver Hepatocellular Carcinoma dataset. We identified 10 methylation-driven genes, which was significantly poorly...
Daylength is a key seasonal cue for animals and plants. In cereals, photoperiodic responses are major adaptive trait, alleles of clock genes such as PHOTOPERIOD1 (PPD1) EARLY FLOWERING3 (ELF3) have been selected in adapting barley wheat to northern latitudes. How monocot plants sense photoperiod integrate this information into growth development not well understood.We find that phytochrome C (PHYC) essential flowering Brachypodium distachyon. Conversely, ELF3 acts floral repressor elf3...
ABSTRACT The effects of postmortem aging time (2, 9, and 16 days) endpoint cooking temperature (60, 70, 80C) on the eating characteristics pork longissimus (LD) muscle were evaluated. Gilts (n=60) from 4 different commercial hybrid genotypes (15 pigs/genotype) selected to produce a range intramuscular fat. Results suggest that LD genotype 2, which was for its propensity increase marbling had higher fat content, tenderness juiciness scores than other (P < 0.05). Increasing 2 days increased...