A5103084043- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Hepatitis Viruses Studies and Epidemiology
- Hepatocellular Carcinoma Treatment and Prognosis
- COVID-19 Clinical Research Studies
- Clinical Nutrition and Gastroenterology
- Systemic Lupus Erythematosus Research
- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Renal Transplantation Outcomes and Treatments
- SARS-CoV-2 and COVID-19 Research
- Renal function and acid-base balance
- Diabetes and associated disorders
- Organ Donation and Transplantation
- Cardiac Arrhythmias and Treatments
- Hemodynamic Monitoring and Therapy
- Retinoids in leukemia and cellular processes
- Hepatitis B Virus Studies
- Long-Term Effects of COVID-19
- Bacterial Infections and Vaccines
- Growth Hormone and Insulin-like Growth Factors
- Drug-Induced Hepatotoxicity and Protection
- Congenital Heart Disease Studies
Pitié-Salpêtrière Hospital
2015-2025
Sorbonne Université
2015-2025
Assistance Publique – Hôpitaux de Paris
2015-2025
Inserm
2018-2025
Université Paris Cité
2025
Centre de Recherche des Cordeliers
2025
CentraleSupélec
2024
Centre de Recherche Saint-Antoine
2018-2023
University of Palermo
2011-2023
Brunel University of London
2023
A low anti-spike antibody response of 28.6% was observed 28 days after BNT162b2 vaccine second dose among 133 solid organ transplant recipients without previous coronavirus disease 2019 (COVID-19). No serious adverse events were recorded. Four severe COVID-19 cases reported between or the 2 doses. Our data suggest to change strategy.
De novo malignancies are one of the major late complications and causes death after liver transplantation (LT). Using extensive data from French national Agence de la Biomédecine database, present study aimed to quantify risk solid organ (excluding nonmelanoma skin cancers) LT. The incidence among all LT patients between 1993 2012 was compared with that population, standardized on age, sex, calendar period (standardized ratio; SIR). Among 11,226 included in study, 1200 were diagnosed...
Small-for-size syndrome (SFSS) is a well-recognized complication following liver transplantation (LT), with up to 20% developing this living donor LT (LDLT). Preventing SFSS involves consideration of factors before the surgical procedure, including and recipient selection, during adequate outflow reconstruction, graft portal inflow modulation, management portosystemic shunts. International Liver Transplantation Society, Living Donor Group, Transplant Society India Consensus Conference was...
Background Genotype 1 (G1) chronic hepatitis C (CHC) patients achieving a rapid virological response (RVR) on pegylated interferon (PEG-IFN) plus ribavirin have high chance of sustained (SVR), influenced by IL28B status, viral load, fibrosis and insulin resistance. We assessed whether 25-hydroxyvitamin D (25[OH]D) serum levels are linked to RVR can be used together with construct pretreatment model predict RVR. Methods A total 117 consecutive G1 CHC were evaluated biopsy anthropometric...
Hepatitis E virus (HEV) can induce chronic infections in the case of immunosuppression, which are sometimes not cured with ribavirin. Furthermore, sofosbuvir is a highly potent inhibitor HCV polymerase and was shown to inhibit HEV genotype-3 replication vitro. We report here outcome sofosbuvir/ribavirin therapy on infection heart transplant recipient non-responder After 24 weeks, regimen failed cure persistent infection, highlighting need therapeutic options for HEV-infected immunosuppressed...
Hepatitis E virus (HEV) infection is increasingly being reported in immunocompromised patients and particularly organ transplant recipients. In this context, HEV frequently evolves to chronic with a rapid progression of fibrosis cirrhosis. Ribavirin monotherapy minimization immunosuppression represent the treatment choice, good response rate. However, no data are available on whether can achieve regression liver patients. A 57-year-old male patient received for alcoholic cirrhosis and, 6...
Single-nucleotide polymorphisms near the interferon lambda 3 (IFNL3) gene predict outcomes to infection and anti-viral treatment in hepatitis C virus (HCV) infection. To identify IFNL3 genotype effects on peripheral blood, we collected phenotype data 400 patients with 1 chronic (CHC). The responder predicted significantly lower white blood cells (WBCs), as well absolute numbers of monocytes, neutrophils lymphocytes for both rs8099917 rs12979860. We sought define WBC subsets driving this...
COVID-19 in a liver transplant recipient: Could iatrogenic immunosuppression have prevented severe
Infections in patients with cirrhosis are associated liver‐related complications (LRCs), especially awaiting liver transplantation (LT). The aim of this study was to evaluate the impact methicillin‐resistant Staphylococcus aureus (MRSA) and extended spectrum beta‐lactamase colonization on infections LRCs for wait list after LT. We retrospectively included 250 483 who were placed LT from December 2015 January 2018. These screened MRSA or beta‐lactamase–producing Enterobacteriaceae (ESBLE) at...