- Bone Tissue Engineering Materials
- Sports injuries and prevention
- Electrospun Nanofibers in Biomedical Applications
- 3D Printing in Biomedical Research
- Sports Performance and Training
- Tendon Structure and Treatment
- Grit, Self-Efficacy, and Motivation
- RNA Interference and Gene Delivery
- Shoulder Injury and Treatment
- Hematological disorders and diagnostics
- Cardiovascular and exercise physiology
- Shoulder and Clavicle Injuries
- Wound Healing and Treatments
- Tissue Engineering and Regenerative Medicine
- Periodontal Regeneration and Treatments
- Thallium and Germanium Studies
- Bone and Joint Diseases
- Magnesium Alloys: Properties and Applications
- Medical and Biological Ozone Research
- Transcranial Magnetic Stimulation Studies
- Graphene and Nanomaterials Applications
- Bone Metabolism and Diseases
- Sports Dynamics and Biomechanics
- Elbow and Forearm Trauma Treatment
- Hemispheric Asymmetry in Neuroscience
Shanghai Jiao Tong University
2020-2024
Ruijin Hospital
2020-2024
University of South Florida
2024
South China Normal University
2023
Beijing Sport University
2023
Shanghai Tenth People's Hospital
2023
Tongji University
2023
Lanzhou Army General Hospital
2017
Metal ions are important trace elements in the human body, which directly affect metabolism and regeneration of damaged tissues. For instance, advanced combination magnesium (Mg2+) bone repair materials make composite have function promoting vascular enhancing adhesion osteoblasts. Herein, inspired by magnets to attract metals, we utilized coordination reaction metal ion ligand construct a bisphosphonate-functionalized injectable hydrogel microsphere (GelMA-BP-Mg) could promote cancellous...
Abstract Microfluidic hydrogel microspheres have been broadly studied across a wide range of industries and applications, their use in the medical field, including control cells drug delivery, is increasing. The usual design these materials intended to enable efficient smart encapsulation and/or drugs which functionalities features are effectively controlled, lending itself some unique properties. These characteristics promote exchanges cooperation multiple disciplines boost development...
Novel gradient bimetallic hydrogel promotes tendon-to-bone interface reconstruction by synchronous regeneration.
Abstract Metal ions play a significant role in tissue repair, with widely application clinical treatment. However, the therapeutic effect of metal is always limited due to metabolization and narrow repair capability. Here, bipolar flexible electrospun fibrous membrane based on metal–organic framework (MOF), which bioinspired by gradient structure tendon‐to‐bone interface, combination regulating osteoblasts differentiation angiogenesis properties, constructed successfully continuous...
In article number 2103339, Ming Cai, Wenguo Cui, and co-workers review the latest developments in controlled delivery of microfluidic hydrogel microspheres, medical applications microspheres to deliver cells drugs are emphasized. This encourages research on boost development precision medicine, new manufacturing technologies, applied materials.
Chronic and infectious wounds are major public health issues with financial clinical manifestations. Developing a multitasking extracellular matrix mimicking scaffold can bring revolution saving millions of lives. Many bioactive agents offering therapeutic promises in managing but require suitable delivery system to ensure not only their bioavailability possible on the wound site also control burst release hence making them either useless or highly cytotoxic. In this study, we reported dual...
Background: Large bone defects resulting from trauma and diseases still a great challenge for the surgeons. Exosomes modified tissue engineering scaffolds are one of promising cell-free approach repairing defects. Despite extensive knowledge variety kinds exosomes promote regeneration, little is known effect mechanism adipose stem cells-derived (ADSCs-Exos) on defect repair. This study aimed to explore whether ADSCs-Exos scaffold promotes Material/Methods: were isolated identified by...
The intracellular delivery of messenger (m)RNA holds great potential for the discovery and development vaccines therapeutics. Yet, in many applications, a major obstacle to clinical translation mRNA therapy is lack efficient strategy precisely deliver RNA sequence liver tissues cells. In this study, we synthesized virus-like mesoporous silica (V-SiO2) nanoparticles effectively therapeutic RNA. Then, cationic polymer polyethylenimine (PEI) was included further surface modification (V-SiO2-P)....
The purpose of the present study was to examine effects 6 weeks 40-, 60-, or 80-cm drop jump (DJ) training on lower limb explosive and change direction (CoD) performance in collegiate Sanda athletes. Repeated-measure ANOVA revealed that there a significant group × time interaction for standing long test (p = 0.006), counter movement 0.026), Illinois agility 0.003), square 0.018), Nebraska 0.027), t 0.032), hexagon 0.012) due best observed at post-test compared with pre-test DJ60 (effect size...
Objectives To compare the clinical outcomes of plate fixation and arthroscopic‐assisted in patients with displaced isolated medium‐sized fractures greater tuberosity. Methods From July 2013 to October 2017, tuberosity who underwent (ASPF group) or open reduction internal (ORIF were retrospectively reviewed analyzed. There 19 ASPF group 27 ORIF group, comparable demographic characteristics. The average age was 49.4 ± 12.1 years 46.9 11.4 group. shoulder function reflected by Constant–Murley...
To investigate the performance of loading naringin composite scaffolds and its effects on repair osteochondral defects.The unloading sustained release microspheres were prepared by W/O/W method; with materials attpulgite collagen type I, naringin, transforming growth factor β 1 (TGF-β 1) constructed respectively "3 layers sandwich method". The effect sustained-release microspheres, morphology scaffolds, biocompatibility evaluated releasing in vitro, scanning electron microscope, cell...
Quantification of fat fraction (FF) and R2* in areas bone marrow edema (BME) metaplasia different stages Ankylosing Spondylitis (AS). 75 AS 3 stage (early acute group, late stable group), 42 BME 39 were detected. Difference FF, compared relationship between FF analyzed. Result showed metaplasia, but not BME, is significantly negative with FF. measurements can quantitatively analyze component change AS.
Since the 1980s, many scholars have studied fatigue from physiological and biochemical aspects. Exercise is a phenomenon caused by exercise stimulation. It reflects tolerance of body to positive process for regulate its own activities has an alarming effect on body's activities. Because appearance, it can reduce intensity exercise, or even stop movement, in order prevent excessive consumption substances damage function. The high load modern tennis training competition will inevitably lead...
Bioscaffolds This schematic diagram is to illustrate the repair effect of a bipolar fibrous membrane in ink painting style with Chinese characteristics. The sky and ground on both sides respectively represents tendon bone. Both MOF particles can promote tissue repair, phoenix used highlight particles. work be found article number 2200072 by Wenguo Cui, Yao Chen, Lei Wang, co-workers.
Abstract:Extrusion 3D printing hydrogels for tissue repair is a research hotspot in recent years.However, the high-fidelity hydrogel process still inseparable from complex cross-linking strategy, which greatly increases difficulty of and limits application field engineering.A that can be printed at room temperature prepared, achieved without any auxiliary during process.The composed gelatin methacrylate (GelMA), Laponite (LPN) methylcellulose (MC).The extrusion test screened out proportion...