A5051550204- Educational Innovations and Challenges
- Regional Economic Development and Innovation
- Genomics and Rare Diseases
- Human Resources and Workforce
- Higher Education Governance and Development
- Cancer Genomics and Diagnostics
- BRCA gene mutations in cancer
- Foreign Language Teaching Methods
- Ethics in Clinical Research
- Genomic variations and chromosomal abnormalities
- Sociopolitical Dynamics in Russia
- Healthcare Systems and Public Health
- Technology and Human Factors in Education and Health
- Educational Methods and Teacher Development
- Regional Socio-Economic Development Trends
- Impulse Buying and Technology Impacts
- Scientific Research and Philosophical Inquiry
- Economic and Technological Systems Analysis
- Higher Education Learning Practices
- Economic and Technological Developments in Russia
- Agricultural Development and Policies
- Advanced Proteomics Techniques and Applications
- Digitalization and Economic Development in Agriculture
- Technology Assessment and Management
- Central Asia Education and Culture
The Russian Presidential Academy of National Economy and Public Administration
2019-2024
University of Technology
2022
Peter the Great St. Petersburg Polytechnic University
2019-2021
Columbia University
2018-2021
Columbia University Irving Medical Center
2018-2021
Genomic knowledge is being translated into clinical care. To fully realize the value, it critical to place credible information in hands of clinicians time support decision making. The electronic health record an essential component clinician workflow. Utilizing present use genomic medicine care improve outcomes represents a tremendous opportunity. However, there are numerous barriers that prevent effective for this purpose. working groups Electronic Medical Records and Genomics (eMERGE)...
We examined the Institutional Review Board (IRB) process at 9 academic institutions in electronic Medical Records and Genomics (eMERGE) Network, for proposed health record-based genomic medicine studies, to identify common questions concerns. Sequencing of 109 disease related genes genotyping 14 actionable variants is being performed ~28,100 participants from sites. Pathogenic/likely pathogenic are returned study participants. each site's research protocols, informed-consent materials,...
Abstract Background Unbiased estimates of penetrance are challenging but critically important to make informed choices about strategies for risk management through increased surveillance and risk-reducing interventions. Methods We studied the clinical outcomes 7 breast cancer susceptibility genes (BRCA1, BRCA2, TP53, CHEK2, ATM, PALB2, PTEN) in almost 13 458 participants unselected personal or family history cancer. identified 242 female with pathogenic likely variants 1 analyses, 147 women...
PurposeTo provide a validated method to confidently identify exon-containing copy-number variants (CNVs), with low false discovery rate (FDR), in targeted sequencing data from clinical laboratory particular focus on single-exon CNVs.MethodsDNA sequence coverage are normalized within each sample and subsequently exonic CNVs identified batch of samples, when the target log2 ratio median exceeds defined thresholds. The quality CNV calls is assessed by C-scores (Z-like scores) using thresholds...
The research article considers an influence of university funding on the development different kind universities. During last 10–15 years a lot strategic documents regarding science and higher education mention importance intensive grow in They should transform to centers instead just facilities, lead scientific field Russia. Presumably such additions management practices as new evaluation, stimulation efficiency improvement instruments mechanisms will increase R&D departments whole...
This research article is devoted to assessing the compliance of quantitative and structural indicators personnel higher education with needs country's economy. The authors try determine main directions for providing economy professional staff resulting tasks that universities face. purpose this compare various structure higher-educated graduates' number in Russia OECD countries (by areas training), find out trends sphere, identify reasons discrepancy between training need them. There studied...
This research article studies the problem of inconsistency higher-educated personnel training structure to current and future sectoral specialization Russian economy. One key tasks higher education system in any country is train who would be demanded by economy future. The responsibility for balancing with needs organizations various industries lies both on government authorities universities themselves. authors analyze correspondence socio-economic development Russia general its regions...
Введение. Приведение объемов и структуры подготовки специалистов среднего звена в соответствие с потребностью кадрах, необходимой для развития экономики регионов, становится особенно актуальным условиях санкционных ограничений, выдвинувших на первый план вопросы обеспечения технологического суверенитета ряда отраслей отечественной экономики. Очевидно, что кадровое обеспечение проектов значимо их успешной реализации не менее, чем разработка масштабное распространение отечественных технологий....
Введение. Ключевой задачей системы профессионального образования является подготовка кадров для экономики регионов. Очевидно, что она должна осуществляться в соответствии с перспективными региональными и отраслевыми потребностями человеческих ресурсах. Однако силу того начала 90-х годов ХХ века обучение осуществляется не только за счет по заказу государства, но договорам об оказании платных образовательных услуг личными предпочтениями абитуриентов их семей, структура подготовки специалистов...
Введение. Прогнозирование и стратегическое планирование перспективных потребностей в рабочей силе развитие среднего профессионального образования регламентированы законодательством Российской Федерации. Вопросы применения современных методов прогнозирования требуют рассмотрения контексте требований установленных норм. Цель. Освещение результатов анализа нормативных методических документов, определяющих вопросы стратегического планирования развития системы Методы. Использованы методы...
This article considers possible approaches to reducing the shortage of personnel with higher education in regional economies and Russian economy as a whole. The imbalance system for training highly qualified specialists industry needs, increasing trend graduates from secondary vocational institutions, reduction working-age population country, increase migration flows labor-deficient regions economically developed ones exacerbate issue both short long term. aim this is consider mechanisms...
How clinicians utilize medically actionable genomic information, displayed in the electronic health record (EHR), medical decision-making remains unknown. Participating sites of Electronic Medical Records and Genomics (eMERGE) Network have invested resources into EHR integration efforts to enable display genetic testing data across heterogeneous systems. To assess clinicians' engagement with unsolicited EHR-integrated test results eMERGE participants within a large tertiary care academic...
The goal of this original research paper is to analyze the state and staffing problems priority directions socio-economic development in Russia reveal required modify approaches within continuous education general higher institutions particular. We here study generalize contents programmes, which support terms staffing, consider questions methodological legal aspects these programmes with regards manpower training. Our has shown that most cases implementation not supported by amount various...
This research article studies the compliance of educational services offer in macroregional (Far Eastern Federal District) system higher education with needs social and economic development territory demand for these services. Accelerating growth potential Far region requires availability training highly qualified personnel to serve a developing economy. The purpose article, as set by authors, was analyse correspondence current future its development, well applicants’ demand. research,...
<title>Abstract</title> The objective of this study is an ontological analysis the digital object (DO), a relatively recent phenomenon that has emerged in relation to performance production enterprises. We analyzed additional benefits economic actors can gain from using DO. This fairly well-understood technical point view; although there are many options for its definition, basic composition and functionality defined clearly, but currently science DO not yet been enough considered. DO, which...
Abstract Purpose: To provide a validated method to confidently identify exon-containing copy number variants (CNVs), with low false discovery rate (FDR), in targeted sequencing data from clinical laboratory particular focus on single-exon CNVs. Methods: DNA sequence coverage are normalized within each sample and subsequently exonic CNVs identified batch of samples (midpool), when the target log 2 ratio median exceeds defined thresholds. The quality CNV calls is assessed by C-scores (Z-like...
The article analyzes the compliance of structure supply and demand for higher education services with staffing needs development Far Eastern Federal District. authors dwell on main market factors affecting (the number potential consumers, monetary incomes population, employment opportunities after graduation, level possible wages in specialty received, price secondary vocational education, economics specialists by groups training areas), their influence macroregion. In context enlarged...
Введение. В предыдущей статье (Коваленко, Федотов, 2024) рассмотрено состояние обеспеченности отдельных отраслей экономики специалистами среднего звена и показано, что нехватка таких специалистов может быть ликвидирована несущественными изменениями в структуре приема на программы подготовки звена. настоящей подробно рассматривается ситуация с обеспеченностью квалифицированными рабочими отрасли «Обрабатывающие производства», проблемы определения базовых для профессий оценки дефицита кадров по...
Recently, there has been an increase in publications devoted to sentinel lymph node biopsy (SLNB) oral cancer. It established that cervical involvement, even small primary tumors, is unfavorable prognostic sign and associated with a more than twofold decrease overall survival. This creates need develop new methods for detecting hidden regional metastases, which, turn, can improve long-term treatment outcomes. Our study included 16 patients tongue cancer cT1-2N0M0 subject selective or...
The article is devoted to the assessment of accessibility education in leading universities Russia for residents different regions country. purpose this publication describe methodology assessing country potential applicants residing certain subjects Russian Federation, and results its testing. provides an analysis level territorial, economic, educational, organizational components bachelor’s specialist programs full-time form relation all country, as well integral indicator from each subject...
The article analyses the dynamics of system higher education in years 2013–2023. Such basic indicators characterising activity postgraduate and doctoral studies as admissions graduations, total number students, ratio volume defended graduations their share average age personnel training specialties corresponding to priority directions development science, technology engineering critical technologies are considered. achieved values compared with planned target for 2013–2014 set out...
This is a concept article proposing trends and methods to improve monitoring of national projects in terms training personnel for professional development programs at all levels. The paper based on analysing Russian international methodologies practices education monitoring. problem precise defining quantitative indicators within implementation significant both universities as part management decision planning government structures, with an information database (correctly representing the...
This article addresses the analysis of demand in education according to further vocational programs and requirements recurrence such for various categories employees. An estimate major directions development system is conducted, based on topics educational programs, types institutions, amount studies.