A5029880926- Genetics, Aging, and Longevity in Model Organisms
- CRISPR and Genetic Engineering
- Microtubule and mitosis dynamics
- Photosynthetic Processes and Mechanisms
- Evolution and Genetic Dynamics
- Circadian rhythm and melatonin
- Genetic Mapping and Diversity in Plants and Animals
- Nanoparticles: synthesis and applications
- Chromosomal and Genetic Variations
Tohoku University
2014-2022
Abstract A ‘sibling’ species of the model organism Caenorhabditis elegans has long been sought for use in comparative analyses that would enable deep evolutionary interpretations biological phenomena. Here, we describe first sibling C . , C. inopinata n. sp., isolated from fig syconia Okinawa, Japan. We investigate morphology, developmental processes and behaviour which differ significantly those The 123-Mb genome was sequenced assembled into six nuclear chromosomes, allowing delineation...
Centrosomes consist of two centrioles and the surrounding pericentriolar material (PCM). The PCM expands during mitosis in a process called centrosome maturation, which scaffold proteins play pivotal roles to recruit other centrosomal proteins. In Caenorhabditis elegans, protein SPD-5 forms polo-like kinase 1 (PLK-1) phosphorylation-dependent manner. However, how phosphorylation promotes assembly is unclear. Here, we identified three functional domains through vivo domain analyses, propose...
Abstract Centrosomes consist of two centrioles and surrounding pericentriolar material (PCM). PCM expands during mitosis in a process called centrosome maturation, which scaffold proteins play pivotal roles to recruit other centrosomal proteins. In C. elegans , the protein SPD-5 forms PLK-1 phosphorylation-dependent manner. However, how phosphorylation promotes assembly is unclear. Here, we identified three functional domains through vivo domain analyses, propose that sequential interactions...