A5101910275- Spinal Cord Injury Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Tissue Engineering and Regenerative Medicine
- Photoreceptor and optogenetics research
- Metabolism and Genetic Disorders
- Nerve injury and regeneration
- Mitochondrial Function and Pathology
- Spinal Dysraphism and Malformations
- Advanced MRI Techniques and Applications
- Neonatal and fetal brain pathology
- Functional Brain Connectivity Studies
- MicroRNA in disease regulation
- Mesenchymal stem cell research
- Curcumin's Biomedical Applications
- Chemical synthesis and alkaloids
- Neurological Disorders and Treatments
- Bacterial Genetics and Biotechnology
- Extracellular vesicles in disease
- Circular RNAs in diseases
- Neuroscience and Neural Engineering
- Immune cells in cancer
- Advanced Neuroimaging Techniques and Applications
- Electrospun Nanofibers in Biomedical Applications
- Neurogenesis and neuroplasticity mechanisms
Nanjing Agricultural University
2024
Yan'an University
2017-2022
Beijing University of Chinese Medicine
2018
People's Hospital of Xinjiang Uygur Autonomous Region
2011
Cancer‑associated fibroblasts (CAFs) exhibit tumor‑stimulating properties and are associated with poor survival in several types of cancer, making them potential therapeutic targets. The present study aimed to determine whether CAFs were cell migration invasion lung squamous carcinoma (LUSC), as well their association microRNA‑369 (miR‑369) these processes. Firstly, the changes malignant biological behavior observed by treating LUSC cells CAFs‑derived extracellular vesicles (CAFs‑EVs)....
BACKGROUND:Microglia reside in the spinal cord plays a key role onset, progression of post-spinal injury (SCI) neuroinflammation. Curcumin has been shown to exhibit diverse anti-inflammatory and anti-tumor activities. The aim this study was explore effect curcumin on inflammatory response lipopolysaccharide (LPS)-activated microglia its mechanism. MATERIAL AND METHODS:The expression levels phosphorylated-p65 (p-p65), tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IκB kinase β (IKKβ)...
The discovery of antibiotics has noticeably promoted the development human civilization; however, antibiotic resistance in bacteria caused by abusing and overusing greatly challenges health food safety. Considering worsening situation, it is an urgent demand to develop emerging nontraditional technologies or methods address this issue. With expanding synthetic biology, optogenetics exhibits a tempting prospect for precisely regulating gene expression many fields. Consequently, attractive...
To investigate the effects of curcumin on motor function, and to explore neuroprotective mechanism after spinal cord injury in rats. The study will theoretical experimental evidence for curcumin's clinical treatment.HI-0400 impactor was used prepare animal models acute injury. One hundred five clean healthy rats were randomly divide into three groups:sham operation group (Sham) (SCI) (SCI+CUR). Intragastric administration administrated 30min model, 1 time a day, until death. SCI+CUR...
Developing effective spinal cord repair strategies for injury (SCI) is of great importance. Emerging evidence suggests that microRNAs (miRNAs) are closely linked to SCI recovery. This study aimed investigate the function miR-34c in neuronal recovery rats with SCI.A rat model was established. Differentially expressed miRNAs were identified by a microarray analysis. MiR-34c expression measured reverse transcription quantitative polymerase chain reaction. Altered or C-X-C motif ligand 14...
This paper uses resting-state functional magnetic resonance imaging to observe the changes in local consistency of brain activity patients with Parkinson's disease (PD). Both healthy volunteers and were scanned for resting imaging, collected raw data processed using processing toolkit software. study adopted use Regional Homogeneity (ReHo). The postprocessing method RS-fMRI is spontaneous cognitive impairment explore function their regions hope providing help treatment impairment. results...
<h3>Objective</h3> To study electrical characteristics after engineering heart tissue (EHT)transplantation in myocardial infarction (MI) SD rat by a new technique of microelectrode arrays (MEA). <h3>Methods</h3> Thirty rats both sexes weighing 220∼250g were sacrificed under chlorine hydrate 0.3 ml/100 mg anaesthesia and randomly divided into three groups: control group (n=10), MI (n=10) transplantation (n=10). The hearts quickly removed Langendorff-perfused with Tyrode9s solution. We...
To observe the effects of different doses acetyl-L-carnitine (ALC) on hindlimb motor function and spinal cord tissue structure in rats with injury. The study will provide theoretical experimental evidences for acetyl-L-carnitine's clinical treatment.Fifty-five SD aged 8-10 weeks were randomly divided into high, medium low-dose drug intervention (SCI + ALC) group, injury group (SCI) sham behavioral evaluation, MAD SOD detection, as well HPLC detection HE staining. BBB scores Rivlin...
Constipation is a common complication in elderly stroke patients. With high incidence, it will aggravate the condition, affect prognosis and lower quality of life Traditional Chinese medical nursing has unique effect on preventing treating poststroke constipation. This paper tries to summarize relevant research as well current traditional theories, medicine prevention treatment characteristic techniques medicine. Meanwhile, also reflect research, offer reference for clinical future. Key...