A5000263795- Immune Response and Inflammation
- Immune cells in cancer
- NF-κB Signaling Pathways
- Chronic Lymphocytic Leukemia Research
- MicroRNA in disease regulation
- Cancer Mechanisms and Therapy
- Angiogenesis and VEGF in Cancer
- Acute Myeloid Leukemia Research
- PI3K/AKT/mTOR signaling in cancer
- Cancer-related molecular mechanisms research
- Essential Oils and Antimicrobial Activity
- Advanced Breast Cancer Therapies
- Bee Products Chemical Analysis
- Phytochemistry Medicinal Plant Applications
- Retinoids in leukemia and cellular processes
- Chemokine receptors and signaling
- Hematological disorders and diagnostics
- Plant Genetic and Mutation Studies
- Quinazolinone synthesis and applications
- PARP inhibition in cancer therapy
- Experimental and Theoretical Physics Studies
- Cancer Immunotherapy and Biomarkers
- FOXO transcription factor regulation
- Electrostatics and Colloid Interactions
- SARS-CoV-2 and COVID-19 Research
Shariati Hospital
2019-2024
Tehran University of Medical Sciences
2018-2024
British Columbia Children's Hospital
2024
University of British Columbia
2024
Georgia State University
2011
Increasing pieces of evidence indicate that inflammatory processes facilitate tumorigenesis; tumor cells simulate the mechanisms by which innate immune produce pro-inflammatory cytokines to exploit them for their own survival and proliferation. Toll-like receptor 4 (TLR4), serves as one most well-known receptors on surface cells, is often expressed ectopically in resulting progression, invasion, chemoresistance. In this study, we examined anticancer effects TAK-242, a small molecule...
Cisplatin-induced ototoxicity remains a significant concern in pediatric cancer treatment due to its permanent impact on quality of life. Previously, genetic association analyses have been performed detect variants associated with this adverse reaction.
Introduction As a vital mechanism of survival, lymphopoiesis requires the collaboration different signaling molecules to orchestrate each step cell development and maturation. The PI3K pathway is considerably involved in maturation lymphatic cells therefore, its dysregulation can immensely affect human well-being cause some most prevalent malignancies. result, studies that investigate this could pave way for better understanding mechanisms, undesired changes lead cancer progression, how...
Propolis is a viscous resinous honeybee-produced substance with numerous medicinal functions; its composition and texture varies according to the geographic location. It considered be promising natural source for management prevention of various pathological conditions. Although several studies have exhibited anti-cancer activity different types propolis, tumor-suppressing potential Kermanian propolis against leukemia cell lines has remained poorly understood. Therefore, current experiment...
In this work, the retarding influence of a gel on rotational motion macromolecule is investigated within framework Effective Medium (EM) model. This an extension earlier study that considered effect translational [Allison, S. et al. J. Phys. Chem. B 2008, 112, 5858-5866]. The modeled as array non-overlapping spherical beads with no restriction placed their size or configuration. Specific applications include right circular cylinders and wormlike chains strings identical touching beads....
The evaluation of TLR1, TLR2, TLR4, TLR7, and TLR8 expression levels in the newly-diagnosed acute myeloid leukemia (AML) patients