Use of topical glaucoma medications has been reported to cause ocular surface (OS) discomfort and inflammation. This study explores the profile inflammatory cytokines OS symptoms induced in response preserved non-preserved drops.Prospective, randomized evaluation on 36 treatment-naïve patients over 24 months three differently drop preparations: Preservative-free (PF), polyquad (PQ) benzalkonium chloride (BAK). Study participants were evaluated at baseline then 1, 3, 6, 12 while medication....

This study aimed to identify the risk factors associated with chronic bronchitis among patients seeking medical attention for respiratory conditions in Al-Najaf Al-Ashraf city, Iraq. The employed a case-control design and recruited 134 participants using convenient sampling. Data was collected questionnaire consisting of four parts which included demographic characteristics, individual factors, family history, seasonal, environmental, nutritional factors. majority were males aged between 21...

The disturbance of typical cellular programmed cell death, known as apoptosis, constitutes a distinctive feature across all categories malignancies. This maladjustment apoptosis has the potential to result in diverse pathological states such cancer, autoimmune illnesses, and neurodegenerative disorders. regulation hinges upon proteins affiliated with BcL-2 family, which possess capacity either foster or impede this progression. exaggerated expression anti-apoptotic (Bcl-2, Bcl-xL, Mcl-1)...

Background: The objectives of this study were: 1) to demonstrate the knowledge married working women regarding benefits breastfeeding; 2) documenttheir intention and practice 3) identify barriers breastfeedingamong thesewomen. Methods: This cross-sectional was conducted during March-April 2014 amongmarried class childbearing age (21-40 years). participants were recruited from seven faculties Kuwait University four private universities which represented in Kuwait. Data collected by usinga...

Numerous research groups across the globe have been dedicatedly studying mechanism involved in carcinogenesis and cancer progression focusing on developing various strategies for prevention treatment of cancer. Chemotherapy is a used whole body to fight recurrent tumors using conventional anticancer drugs which can be made more effective by chemosensitizers, decrease required dosage treatment. TDP-1 inhibitors potential enhance effectiveness topotecan increasing sensitivity drug, both...

Background: Certain chromium compounds are prominent metal carcinogens in both occupational and environmental settings.Objectives: The present study aimed to determine cytogenetic changes the form of sister chromatid exchanges (SCEs) predict carcinogenicity steel foundry workers; moreover, relationships between SCEs tumor marker (CA 15-3) with urinary levels same group.Subjects methods: included three groups; 20 apparently healthy male workers, from different work sections, workers not...

Purpose: There is an increased risk of bone disease and fractures in ulcerative colitis (UC) patients treated with corticosteroids (CS). The American Gastroenterology Association (AGA) issued guidelines for density screening UC patients. aim this study was to assess the adherence these benefits Dual-Energy-X-ray-Absorptiometry (DXA) among CS-treated Methods: Nationwide Veterans Affairs system (VA) data obtained. followed up VA between 2001 2011, occurrence fragility were identified using...

Infant feeding practices comprising of both the complementary as well breast-feeding has major roles in determining nutritional status child. Worldwide, it is estimate that only 34.7% infants are exclusively breastfed for first 6 months life, majority receiving some other fluid or food beginning early months. Assess child-feeding with special emphasis children between six-three years age. This study cross-sectional was carried out an urban population Nasiriya city from Bint-Alhuda Teaching...

Background: Streptococcal tonsillitis is a common pediatric ailment which faced by physicians on daily basis and associated with disastrous complications if not treated adequately. The objective of this study was to compare the efficacy, safety cost-effectiveness intravenous co-amoxiclav benzyl penicillin in treatment severe streptococcal children.
 Material Methods: This Randomized Controlled Trial carried out at CMH Mardan, Khyber Pakhtunkhwa from January 2018 November 2019. A total...

Background: Children under five years of age suffer from anemia is a common medical problem worldwide.Iron deficiency the most prevalent in infants and has proven to be public health issue. Manystudies have been conducted on among but scope studies focused anemiaprevalence with less emphasis knowledge parental practice.Objective: To explore level knowledge, attitude, practice towards iron anemia.Method: A cross-sectional study first taken 150 children that attended Children’s Counseling...

Introduction: Colon cancer is the third most common in men and women. Colonoscopy an effective screening test for colon leading to decrease incidence mortality from colorectal (CRC). High-quality colonoscopy best prevention against interval CRC critical predict subsequent surveillance, which based on quality of baseline colonoscopy. The this procedure highly operator dependent. American society gastrointestinal endoscopy college gastroenterology have published recommendations measures...

Purpose: There is limited data regarding clinical outcomes in patients with ulcerative colitis (UC) who require early corticosteroids (CS) use after diagnosis. Our aim was to evaluate CS utilization (within 30 days of diagnosis) as a predictive marker for long-term (colectomy, steroid dependence, thiopurine utilization) population-based cohort incident UC cases. Methods: Nationwide obtained from the Veterans Affairs (VA) healthcare system period 2001-2011. Patients were included if they had...

Background:Science teachers are the closest to health. Teachers must be aware of transitional diseases prevalent within school setting. As well as provide educational lessons on ways transmission and reduce incidence infection explain importance vaccines that consider primary prevention about disease this is done through coordination with centers health care in Iraq. Methods material Study: The study design for quiz-experimental conducted at education directorate Al-Muthanna City, during...

Objective: In this study, we report that a novel combination therapy of different statins with Ibrutinib can overcome such resistance. Methods: For this, generated cell line model, exhibiting resistance to Ibrutinib, by repeated exposure mantle lymphoma Ibrutinib. Apoptosis was assessed the extent phosphatidylserine externalisation. Results: Our results indicated could be targeting key enzyme, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase in cholesterogenesis pathway. Conclusion:...

Background: Primary hypothyroidism is rarely described in Aisan medical publications except, of course, a few allusions made the study endemic goitre. Patients and methods: A prospective was conducted among patients coming to consultation or hospitalized internal medicine service, Point Baqai Institute Diabetology Endocrinology Karachi from September 2021 2022. The inclusion criteria were clinical signs thyroid-stimulating hormone dosage. parameters taken into account sociodemographic,...