A5008675328- Immune cells in cancer
- Epigenetics and DNA Methylation
- Histone Deacetylase Inhibitors Research
- Carcinogens and Genotoxicity Assessment
- Immune Cell Function and Interaction
- Toxic Organic Pollutants Impact
- Genomics, phytochemicals, and oxidative stress
- Microbial bioremediation and biosurfactants
- Monoclonal and Polyclonal Antibodies Research
- HER2/EGFR in Cancer Research
- Agricultural Practices and Plant Genetics
- Emergency and Acute Care Studies
- Agricultural pest management studies
- Metamaterials and Metasurfaces Applications
- Disaster Response and Management
- Trauma and Emergency Care Studies
- Antenna Design and Analysis
- Polyamine Metabolism and Applications
- Cancer Treatment and Pharmacology
- Cancer-related gene regulation
- Energy Harvesting in Wireless Networks
- Pesticide Exposure and Toxicity
- PI3K/AKT/mTOR signaling in cancer
Zhejiang University
2014-2023
CMH Lahore Medical College and Institute of Dentistry
2023
Rawalpindi Medical University
2016
M2 polarized tumor-associated macrophages (TAMs) have a multifunctional role in cancer initiation, progression, metastasis, and contribute to chemotherapeutic resistance. Therefore, identifying TAMs is potential target for therapeutic intervention. The underlying mechanism that the remains primarily uncharacterized; however, only few compounds been identified inhibit macrophages. In this research, we investigated lapatinib could effectively suppress expression of IL_13-induced surface...
ABSTRACT Polychlorinated biphenyls (PCBs) are a group of chemicals that persist in the environment, indoors, and humans. Lung exposure to airborne food contaminants, such as PCBs, may cause possible lung disorders, cancer. In present study, we investigated effects structurally different lower chlorinated (≤4Cl), noncoplanar PCB40, coplanar PCB77 on human fibroblast cell line (HELF) proliferation, cycle progression, molecular mechanisms. Noncoplanar PCB40 exhibited concentration‐...
The present study used human lung fibroblast (HELF) cells as a test model to evaluate the role of oxidative stress (OS) and extracellular signal-regulated kinases 1/2 (ERK1/2) protein in HELF cell proliferation exposed PCB118. Results from 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide demonstrated that PCB118 at lower concentrations stimulated abrogate proliferative effect higher dose time-dependent manner. Moreover, reactive oxygen species, malondialdehyde (MDA), superoxide...