A5100446225- Glioma Diagnosis and Treatment
- MicroRNA in disease regulation
- Atmospheric chemistry and aerosols
- Ferroptosis and cancer prognosis
- Cancer Mechanisms and Therapy
- Cancer Immunotherapy and Biomarkers
- Pituitary Gland Disorders and Treatments
- Light effects on plants
- Cytokine Signaling Pathways and Interactions
- Atmospheric Ozone and Climate
- Microtubule and mitosis dynamics
- Kruppel-like factors research
- Nanoplatforms for cancer theranostics
- Plant responses to elevated CO2
- Atmospheric and Environmental Gas Dynamics
- Epigenetics and DNA Methylation
- interferon and immune responses
- Cancer Cells and Metastasis
- Neuroblastoma Research and Treatments
- Endometriosis Research and Treatment
- Neuroendocrine Tumor Research Advances
- RNA modifications and cancer
- Immunotherapy and Immune Responses
Jinan University
2019-2024
First Affiliated Hospital of Soochow University
2020-2024
Soochow University
2019-2024
ShenZhen People’s Hospital
2024
Southern University of Science and Technology
2022
Beijing Luhe Hospital Affiliated to Capital Medical University
2018
Huazhong University of Science and Technology
2015
Background: Mitochondria are the center of cellular metabolism. The relationship between mitochondria and diseases has also been studied for a long time. However, prognostic role mitochondrial-related genes (MRGs) in patients with glioma their biological effects still unclear. aim study was to construct mitochondria-related model assess prognosis potential like immune infiltration, gene pathway mutation, give some predictive chemotherapeutic agents.
Abstract Background Cancer‐specific autoantibodies found in serum of cancer patients have been characterized as potential predictors the high risk recurrence and treatment response. The objective this study is to investigate clinical utility O‐6‐methylguanine‐DNA methyltransferase (MGMT) novel biomarkers for prediction response glioma through MGMT peptides microarray. Methods A total 201 samples with various WHO grade 311 healthy donors were examined detection by value was studied...
Angiogenin is a small protein that exerts potent stimulating effects on angiogenesis. In this study, we aimed to examine the expression of angiogenin in different subtypes glioblastoma and estimated its independent prognostic value.The genomic survival data from The Cancer Genome Atlas-glioblastoma were extracted for secondary study. Results was upregulated tissues varied significantly subtypes. Although proneural subtype had lowest expression, high associated with worse overall survival....
Glioblastoma (GBM) is a very frequent primary tumour in the cerebrospinal nervous system. Temozolomide (TMZ) first-line treatment for patients with GBM. However, some of GBM do not respond to TMZ. O6-methylguanine-DNA-methytransferase (MGMT) remains major cause. In previous study, we detected antibodies against MGMT peptides glioma, and five highly responsive autoantibodies anti-MGMT-02, anti-MGMT-04, anti-MGMT-07, anti-MGMT-10, anti-MGMT-18 were identified that could be used dynamically...
Objective: High grade astrocytoma (HGA) as an aggressive brain tumor, is always correlated with poor prognosis. In this paper, we aimed to explore the genetic prognostic biomarkers for HGA.Methods: The genome-wide expression profile of 26 tumor samples obtained from patients HGA was downloaded Gene Expression Omnibus. risk genes prognosis were identified and verified by data in TCGA database. Protein–protein interaction (PPI) network factor constructed significant module screened. Function...
Objective To explore the role of radiotherapy in treatment primary central nervous system lymphoma. Methods Clinical data 60 patients diagnosed with lymphoma from September 2010 to December 2017 were retrospectively analyzed. Among them, 50 cases by histopathological examination after stereotactic biopsy or tumor resection and 10 gadolinium enhanced magnetic resonance imaging (MRI). Fifty-two underwent chemotherapy, 45 them received methotrexate-based 25 rituximab-based regimen....