A5007274790- Hormonal Regulation and Hypertension
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Adrenal and Paraganglionic Tumors
- Pneumonia and Respiratory Infections
- Cardiovascular Disease and Adiposity
- Extracellular vesicles in disease
- Regulation of Appetite and Obesity
- Higher Education Teaching and Evaluation
- Streptococcal Infections and Treatments
- Stress Responses and Cortisol
- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Inclusive Education and Diversity
- Blood Pressure and Hypertension Studies
- Immunodeficiency and Autoimmune Disorders
- Adrenal Hormones and Disorders
- Renin-Angiotensin System Studies
- Education and Teacher Training
Pontificia Universidad Católica de Chile
2021-2025
Millennium Institute on Immunology and Immunotherapy
2021
Universidad de Las Palmas de Gran Canaria
2006-2010
Observatorio de la Inmigración de Tenerife
2010
A large proportion of patients with low-renin hypertension (LRH) correspond to primary aldosteronism (PA). However, some these subjects have low normal aldosterone. Since renin is driven by excessive mineralocorticoids or glucocorticoids acting on mineralocorticoid receptors (MRs), we hypothesize that a low-cortisone condition, associated classically 11βHSD2 deficiency, proxy chronic MR activation cortisol, which can also lead renin, elevated blood pressure, and renal vascular alterations.
Premenopausal women (PreM) have a cardioprotective advantage over postmenopausal (PostM) due to estrogen. The interaction of estrogen with the mineralocorticoid receptor (MR) pathway remains unexplored. This study aimed identify changes in aldosterone, renin and sexual steroid levels MR surrogate biomarkers PostM that may explain blood pressure renal damage. A cross-sectional was carried out 47 normotensive hypertensive Chilean distributed between PreM PostM. Clinical, anthropometric...
<title>Abstract</title> In obesity,white adipose tissue (WAT) undergoes hypertrophic and hyperplastic changes that are driven by phenotypical in preadipocytes adipocytes. WAT also causes a chronic inflammatory state modifies gene expression the secretome, including shedding of adipose-derived extracellular vesicles (AdEVs) into circulation, with these AdEVs affecting other cell types potentially modifying their phenotypes. <bold>Aim: </bold>To evaluate effects on renal endothelial cells...
Primary aldosteronism (PA) is the most common cause of secondary hypertension and reaches a prevalence 6-10%. PA an endocrine disorder, currently identified as broad-spectrum phenotype, spanning from normotension to hypertension. In this regard, several studies have made advances in identification mediators novel biomarkers specific proteins, miRNAs, lately, extracellular vesicles (EVs) their cargo. Aim To evaluate lipocalins LCN2 AGP1, urinary EV miR-21-5p Let-7i-5p for PA. Subjects Methods...
Abstract Disclosure: J.A. Pérez: None. A. Tapia-Castillo: Martinez: P. Carrion: M. Hernandez: R. Pinilla: C.E. Fardella: C.A. Carvajal: Primary aldosteronism (PA) is caused by aldosterone producing adenoma, bilateral adrenal hyperplasia and genetic forms, including familial hyperaldosteronism type I (FH-I). Patients with FH-I exhibit high levels of leading to several arterial hypertension (AHT), left ventricular hypertrophy (LVH) other cardiovascular manifestations such as endothelial...
Strength training is usually associated with increase muscle mass, strength and power while fat mass reduced. Thus, may also have an influence in plasma leptin concentration or the relationship between leptin. PURPOSE: The aim of this study was to assess if 7–8 weeks combined plyometric exercises without any nutritional intervention results a significant reduction alters young women. METHODS: Seventeen physical education students were randomly assigned either control group (CG) (n=10) (ST)...