A5024962518- Ovarian function and disorders
- Ovarian cancer diagnosis and treatment
- Growth Hormone and Insulin-like Growth Factors
- Hormonal and reproductive studies
- Sexual Differentiation and Disorders
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Hormonal Regulation and Hypertension
- Estrogen and related hormone effects
- Neuroblastoma Research and Treatments
- Birth, Development, and Health
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Reproductive Biology and Fertility
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Respiratory Support and Mechanisms
- Reproductive tract infections research
- Gestational Trophoblastic Disease Studies
- Urological Disorders and Treatments
- Menopause: Health Impacts and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Airway Management and Intubation Techniques
- Social Issues and Sustainability
- Metabolism and Genetic Disorders
- Ethics and bioethics in healthcare
Pontificia Universidad Católica de Chile
2016-2025
Monash University
2020
Clínica Alemana
2019
Hospital Universitario de Guadalajara
2002-2018
Blood pressure (BP) regulation is a complex process involving various hormones, including aldosterone and its mineralocorticoid receptor. Mineralocorticoid receptor expressed in several tissues, the kidney, plays crucial role regulating BP by controlling sodium water balance. During different stages of life, hormonal changes can affect activity levels, leading to BP. Increasing evidence suggests that sex steroids modulate levels. Estrogens, particularly estradiol, mediate biosynthesis...
Premenopausal women (PreM) have a cardioprotective advantage over postmenopausal (PostM) due to estrogen. The interaction of estrogen with the mineralocorticoid receptor (MR) pathway remains unexplored. This study aimed identify changes in aldosterone, renin and sexual steroid levels MR surrogate biomarkers PostM that may explain blood pressure renal damage. A cross-sectional was carried out 47 normotensive hypertensive Chilean distributed between PreM PostM. Clinical, anthropometric...
Summary Objective Thyroid dysfunction and obesity during pregnancy have been associated with negative neonatal obstetric outcomes. hormone reference ranges not established for the pregnant Hispanic population. This study defines thyroid early in Chilean women evaluates associations of body mass index ( BMI ) function. Design, patients, measurements is a prospective observational 720 healthy attending their first prenatal consultation at an outpatient clinic. function [ TSH , Free T4, Total...
Abstract Importance After menopause, estradiol (E2) is predominately an intracrine hormone circulating in very low serum concentrations. Objective The objective of this work to examine determinants E2 concentrations women beyond age 70 years. Design and Setting A cross-sectional, community-based study was conducted. Participants total 5325 participated, with a mean 75.1 years (± 4.2 years) not using any sex steroid, antiandrogen/estrogen, glucocorticoid, or antiglycemic therapy. Main Outcome...
Molecular testing contributes to improving the diagnosis of indeterminate thyroid nodules (ITNs). ThyroidPrint® is a ten-gene classifier aimed rule out malignancy in ITN. Post-validation studies are necessary determine real-world clinical benefit patients with A single-center, prospective, noninterventional utility study was performed, analyzing impact physicians' decisions for Demographics, nodule characteristics, benign call rates (BCRs), and surgical outcomes were measured....
Postmenopausal hyperandrogenism constitutes a very rare condition of tumoral or non-tumoral origin primarily residing either in the ovary adrenal glands. We present herein two cases with this condition; one abnormal postmenopausal genital bleeding and mild increase facial hair, second slow-developing hirsutism virilization. Both shared notorious libido.The laboratory tests showed high levels testosterone (>100 ng/ml). A normal value dehydroepiandrosterone sulfate cortisol level at 9 am after...
Low flow nasal cannula (LFNC) are frequently used in preterm infants. However, the delivered inspired oxygen concentration and airway pressures not well established.To determine fraction of (FiO2 ) hypopharyngeal generated by LFNC at different gas flows, mixture concentrations infant's weight.Serial samples were obtained 33 very low birth weight infants who receiving with LFNC. Measurements flows concentrations. FiO2 was measured using an electrochemical cell analyzer a pressure...
Hypophosphatemia is a relatively frequent and potentially serious adverse drug effect. Clinically it characterized by bone pain muscle weakness. There are several mechanisms which can induce hypophosphatemia they be classified according to whether or not mediated an excess of Fibroblast Growth Factor 23 (FGF23). We report two patients with the condition: (i) A 49-year-old woman Chronic Myeloid Leukemia (CML) gastric sleeve surgery at 46 years age. After receiving intravenous carboxymaltose...
We describe a 67-year-old woman with postmenopausal bleeding having ceased estrogen plus progestogen therapy nine months before. Transvaginal ultrasonography showed endometrial thickening normal ovarian appearance. Hormonal studies revealed high estradiol and inhibin B levels but androgens adrenal hormones. Magnetic resonance image demonstrated 13-mm left tumour. Hysterectomy bilateral salpingo-oophorectomy were performed, the pathological study an 8 mm thecoma. This case illustrates very...
Introducción. Potenciar la participación de las mujeres durante el embarazo y parto se alinea con llamado Organización Mundial Salud vincula efectos en satisfacción usuaria, resultados clínicos salud una mejor gestión los prestadores salud. Objetivo. Descubrir necesidades toma decisiones proceso del parto. Método. Análisis secundario un estudio cualitativo descriptivo hospitalizadas servicio puerperio dos hospitales Santiago Chile. El análisis datos realizó utilizando método propuesto por...